Weekly OHDSI Digest – November 6, 2023


Please join our Nov. 7 Community Call (11 am ET) for a special session honoring the 2023 Titan Award recipients. Community members nominate fellow collaborators who they believe have made a significant impact on advancing OHDSI’s mission over the last year, and these eight leaders were honored at the 2023 Global Symposium. Join us Tuesday to hear about their work over the last year, and how they helped move OHDSI forward heading into 2024. The winners were:

Data Standards: Gowtham Rao and Azza Shoaibi

Methodological Research: Jiayi (Jessie) Tong

Open-Source Development: Katy Sadowski

Clinical Applications: Center for Surgical Science

Community Leadership: Nicole Pratt

Community Collaboration: Cynthia Sung

Community Support: Gyeol Song

Everybody is invited. Calendar invites went out last week. If you did not receive one, please use this link to join the meeting. All recordings from these weekly calls are available within our Teams environment and will be posted on both our YouTube page and our OHDSI.org Community Calls page.


Upcoming Workgroup Calls – OHDSI


The 2023 Global Symposium home page has posted the video presentations and slides for all of the Friday talks, as well as the “Introduction to OHDSI” tutorial from Saturday morning. All posters from the collaborator showcase are also available. Please check out this page for all material related to the event.

• The Nov. 14 OHDSI call will welcome our Collaborator Showcase Best Contribution winners to present their work and take questions from the community. Congratulations to the following honorees:
Observational Data Standards and Management: Augmenting the National COVID Cohort Collaborative (N3C) Dataset with Medicare and Medicaid (CMS) Data, Secure and Deidentified Clinical Dataset
Methodological Research: Generating Synthetic Electronic Health Records in OMOP using GPT
Open-Source Development: GUSTO Data Vault: Laying the foundations for an open science system with OMOP Data Catalogue
Clinical Applications: Patient’s outcomes after endoscopic retrograde cholangiopancreatography (ERCP) using reprocessed duodenoscope accessories: a descriptive study using real-world data

• The latest edition of The Journey newsletter is now available, and it includes information on the OHDSI Symposium, recent community updates, publications/presentations from October, and plenty more. You can access the newsletter here, and you can subscribe to receive future newsletters here.

• Atif Adam is a systems scientist and researcher boasting over a decade of diversified experience spanning academia, industry, and entrepreneurial ventures. He attained his doctorate in Health Systems Science and Computational Epidemiology. In addition, Dr. Adam completed his clinical training in Internal Medicine and secured master’s degrees in Health Policy and Spatial Epidemiology. Relatively new to the community, he has taken a leadership role within the Health Equity workgroup, and he joined both the Steering Group and 2023 Scientific Review committee. He discusses his career journey, challenges in health equity and how OHDSI is dealing with them, advice for newcomers in OHDSI, and plenty more in the latest Collaborator Spotlight.

 The latest edition of the Our Journey annual report was shared at the Global Symposium, but there is a digital version that you can access on the OHDSI website.

• Research from both the 2023 Global Symposium Collaborator Showcase can be viewed on the Global Symposium Showcase page. Research is also being shared daily on OHDSI’s LinkedInTwitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — Conversion of a Myositis Precision Medicine Center into a Common Data Model: A Case Study (Zachary Wang)

Tuesday – Making NLP-derived data actionable within the OHDSI ecosystem (Michael Gurley)

Wednesday – Demonstrating Utility of the Edge Tool Suite through Clinical Trial Emulation (Ruth Kurtycz)

Thursday – OHDSI Network Study Execution Framework and Templating (Ben Martin)

Friday – Using Contrastive Principal Component Analysis to Identify Post-acute Sequelae of SARS-CoV-2 Infection Subphenotypes: an EHR-Based Cohort from the RECOVER Program (Xiaokang Liu)

• The new Community Dashboard is available on OHDSI.org. The dashboard includes tracking sites for publicationsYouTube videosEHDEN Academy coursesnetwork studiesthe phenotype explorer, and opportunities.

HADES Developer Announcements

• Martijn Schuemie announced the release of SeflControlledCaseSeries 5.0.0. This major release is focused on adjusting for temporal trends. Some important innovations: 1) Better diagnostic for temporal stability; 2) Option to automatically restrict study time to when the drug was on the market (i.e. the time it was observed in the database); and 3) Ability to define multiple study periods. The main use case is excluding the time of the COVID-19 pandemic, when most clinical events show temporal instability.

• Egill Fridgeirsson announced the release of DeepPatientLevelPrediction 2.0.1. This is mostly a bug fix release and improvements to the documentation based on feedback from the HADES hackathon.

• Katy Sadowski announced the release of DataQualityDashboard 2.5.0. This release contains a new function contributed by Jared Houghtaling. The new function, writeDBResultsToJson, can be used to export DQD results from a database table into a JSON file. This release also contains some bugfixes including fixing some queries that were broken for users who store their vocab in a separate schema from the CDM, and allowing DQD to run even if the CDM_SOURCE table has multiple rows (previously it was throwing an error).

• Gowtham Rao announced the release of CohortExplorer 0.1.0. There is new functionality that adds a ‘Feature Cohort’ domain based on instantiated cohorts. This is useful for case adjudication. Use case example: look for 1 symptom cohort of dyspnea vs every concept for dyspnea while adjudicating a pneumonia cohort.

Job Openings

• Ajit Londhe recently posted that Boehringer Ingelheim is hiring for two positions: (1) Director, Real World Data & Analytics – Data Domain Owner (this position will lead acquisition strategy for real-world data sources for possible in-license/ purchase and additional analytical tools for in-house analytic needs across the organization … responsible for oversight of operational governance tasks & real-world data life cycle governance … US-based, remote location); and (2) Real World Evidence Data Engineer (IT position supporting RWE teams’ technology needs, including OHDSI stack support … based in Spain only).

• Yuan Lu, Assistant Professor at Yale University, announced an opening for a Postdoctoral Associate/Data Analyst at the Yale University School of Medicine. This person will work on the LEGEND Hypertension Project. More information, including job description, key responsibilities and qualifications, are available here. If interested, please reach out to Dr. Lu at y.lu@yale.edu


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