Weekly OHDSI Digest- December 21, 2020

OHDSI STATEMENT ON COVID-19 OHDSI is committed to doing what it can to support and inform the COVID-19 pandemic response, and will prioritize activities aligned to this effort. As we adjust to the current global situation, the OHDSI community will continue to have our regular Tuesday community calls, as well as our various working group calls. Understandably, some calls could be postponed or cancelled due to issues surrounding COVID-19, so we ask that you continuously check the OHDSI forums, weekly digest and social channels for updated information. OHDSI is a virtual community, so we are equipped to continue collaboration during this challenging time.


Oncology – Genomic Subgroup- Tuesday, December 22 at 9am ET
Meeting link:https://us04web.zoom.us/j/412862164?pwd=NmpEWTdTQlB4N3VxT0tQRXdDWlg0dz09
(The next meeting on January 5, 2021, will take place in MS Teams; new link to come)

Oncology – Development Subgroup- Wednesday, December 23 at 10am ET
Meeting link: https://zoom.us/j/780765541?pwd=RTVsRUVFdU4xV1BFZ2ZuVnJDVUVrdz09
(The next meeting on January 6, 2021, will take place in MS teams; new link to come)

GIS-Geographic Information System WG- Wednesday, December 23 at 2pm ET
Meeting link: https://tufts.webex.com/webappng/sites/tufts/meeting/download/e4252c4b631b47d6a7aeaa41f4d14194?siteurl=tufts&MTID=m50babe50fb48492079bf541cc9ae8148

Please note that the Oncology – Leadership Subgroup meeting, is cancelled for Dec. 22.


Video Recordings from 2020 OHDSI Symposium – Recordings from the 2020 OHDSI symposium day have been made available here: https://www.ohdsi.org/2020-ohdsi-global-symposium/

Accessing MSTeams – OHDSI meetings are transitioning to MSTeams. If you attended the 2020 OHDSI Symposium, you are already in the OHDSI teams environment. If you would like to be added to the OHDSI teams environment, please fill out this form: https://forms.office.com/Pages/ResponsePage.aspx?id=lAAPoyCRq0q6TOVQkCOy1ZyG6Ud_r2tKuS0HcGnqiQZUQ05MOU9BSzEwOThZVjNQVVFGTDNZRENONiQlQCN0PWcu

If you are already in the OHDSI teams environment and you would like to join work groups in teams, please fill out this form: https://forms.office.com/Pages/ResponsePage.aspx?id=lAAPoyCRq0q6TOVQkCOy1ZyG6Ud_r2tKuS0HcGnqiQZUOVJFUzBFWE1aSVlLN0ozR01MUVQ4T0RGNyQlQCN0PWcu
*note that not all work groups are currently taking place in teams but we plan to transition shortly

APAC Symposium : The six regional breakout session videos (Australia, China, Japan, Korea, Singapore and Taiwan) have all been posted to the APAC Symposium page: https://www.ohdsi.org/2020-ohdsi-apac-symposium/

OHDSI Community Call: The next OHDSI Community call is the week of Jan. 11-15; more information will be shared during the first weekly digest of 2021.


Effects of Age, Sex, Race/Ethnicity, and Allergy Status in Obesity-Related Pediatric Asthma | American Academy of Pediatrics (aappublications.org)
This was a large retrospective cohort study from 8 Pediatric institutions in the United
States that were a part of PEDSNet (National Pediatric Clinical Network for Research), utilizing
data through the Observational Health Data Sciences and Informatics ( OHDSI ) common

Prediction of Major Depressive Disorder Following Beta-Blocker Therapy in Patients with Cardiovascular Diseases

2 days ago – Incident depression has been reported to be associated with poor prognosis in
patients with cardiovascular disease (CVD), which might be associated with beta-blocker
therapy. Because early detection and intervention can alleviate the severity of depression …

Renin–angiotensin system blockers and susceptibility to COVID-19: an international, open science, cohort analysis

3 days ago – Background Angiotensin-converting enzyme inhibitors (ACEIs) and
angiotensin receptor blockers (ARBs) have been postulated to affect susceptibility to COVID-
19. Observational studies so far have lacked rigorous ascertainment adjustment and …

A scalable surrogate L0 sparse regression method for generalized linear models with applications to large scale data

3 days ago – This paper rigorously studies large sample properties of a surrogate L 0
penalization method via iteratively performing reweighted L 2 penalized regressions for
generalized linear models and develop a scalable implementation of the method for sparse …

Outlier concepts auditing methodology for a large family of biomedical ontologies

6 days ago – Summarization networks are compact summaries of ontologies. The “Big
Picture” view offered by summarization networks enables to identify sets of concepts that are
more likely to have errors than control concepts. For ontologies that have outgoing lateral …

Advances in particle size analysis with transmitted light techniquesD Wirz, HJ Bart – BULGARIAN CHEMICAL COMMUNICATIONS – bcc.bas.bg

9 days ago – … measurement techniques. The Optical Multimode Online Probe ( OMOP ) for
droplet size analysis based on a shadowgraphic transmitted light approach was further
developed for bubbles or solids in liquids or even droplets in sprays. A …

Transformation of Pathology Reports Into the Common Data Model With Oncology Module: Use Case for Colon Cancer

12 days ago – … The Observational Medical Outcomes Partnership ( OMOP ) CDM is used in
distributed research networks for clinical data; however, it requires conversion of free text–based
pathology reports into the CDM’s format. There are few use cases of representing cancer data …

Transformation of Pathology Reports Into the Common Data Model With Oncology Module: Use Case for Colon Cancer

12 days ago – … that can utilize both clinical and omics data. The essential text entities from
the pathology reports are extracted, standardized, and converted to the OMOP CDM
format in order to utilize the pathology data in cancer research …