Weekly OHDSI Digest-April 17, 2023


Please join our April 18 community call (11 am ET) for the fourth tutorial in our Save Our Sisyphus Challenge. This session will provide an in-depth discussion on phenotype evaluation, and it will be led by:

• Azza Shoaibi (Associate Director, Janssen Research and Development, Inc.)

• James Gilbert (Manager, Epidemiology Analytics, Janssen Research and Development, Inc.)

Please remember that all recordings, as well as key links for this event, are available on the SOS Challenge homepage.

Everybody is invited. Calendar invites went out last week. If you did not receive one, please use this link to join the meeting. All recordings from these weekly calls will be posted on both our main OHDSI Teams tenant and on our OHDSI.org Community Calls page.

SOS Challenge Week 4 • Focus: Phenotype Evaluation

Tutorial 1: Azza Shoaibi/ James Gilbert (Tuesday, 11 am ET): Meeting Link

Tutorial 2: Evan Minty/ James Gilbert (Tuesday, 7 pm ET): Meeting Link

Office Hours with Azza Shoaibi (Friday, 9-10 am ET): Meeting Link

For more information on the SOS Challenge, links to study-related materials, schedules, meeting links and more, please visit the event homepage.


Upcoming Workgroup Calls – OHDSI


Congratulations to the team of Stéphane Meystre, Paul Heider, Andrew Cates, Grace Bastian, Tara Pittman, Stephanie Gentilin, and Teresa Kelechi on the publication of Piloting an automated clinical trial eligibility surveillance and provider alert system based on artificial intelligence and standard data models in BMC Medical Research Methodology.


DevCon 2023 will be held virtually this Friday from 9 am – 3 pm ET (link: join DevCon here). The full agenda is available at the event homepage. The event will feature 11 short talks around five topics in the first session, followed by a trio of afternoon workshops that focus on significant topics for sustained success within our open-source community during the second session. Thank you to Adam Black and Paul Nagy for organizing this event.

• The deadline to participate in the OHDSI European Symposium is quickly approaching. The European call for participation, which is accepting submissions for posters and software demonstrations to be presented during the July 3 collaborator showcase, will conclude on Sunday, April 30.

• The last two sessions of the Early-Stage Researchers Career Speaker Series are now available on our YouTube channel: Seng Chan You (March) and Anna Ostropolets (April).

• The new Community Dashboard is now available on OHDSI.org. The dashboard includes tracking sites for publicationsYouTube videosEHDEN Academy coursesnetwork studiesthe phenotype explorer, and opportunities.

HADES Development Announcements

• Martijn Schuemie announced the releases of SqlRender 1.14.0 (contains some fixes for Spark, Oracle, Netezza, and PostgreSQL), DatabaseConnector 6.2.0 (a large set of fixes for DataBricks), SelfControlledCaseSeries 4.2.0 (fixes a bug that caused regularization to not be applied to calendar-time splines), and CohortMethod 5.0.0 (this a major update with many changes, including a major overhaul of the framework for running multiple analyses. There are no guarantees for backwards compatibility, so please read the changelog carefully. This version should provide greater flexibility and stability than before.)

• Joel Swerdel announced the release of PheValuator 2.2.6, which creates an export folder with a set of results from the analysis as well as diagnostics for the run. This csv files may be used in shiny applications. Joel also posted a new PheValuator tutorial, which you can watch here.

• Marc Suchard announced the release of BrokenAdaptiveRidge v1.0.0, which is now part of HADES. This package enables approximate L0 (best subset) regression at scale using Cyclops. He also announced that Cyclops v3.3.1 has been released and is now on CRAN. This features the introduction of Jeffreys prior and several fixes for likelihood profiling.

• Egill Fridgeirsson announced the release of DeepPatientLevelPrediction 1.1.3. This was a minor fix for the CI. Our main dependancy, torch in R, wasn’t installing correctly since a new release of it was released on CRAN.

Thank you to all HADES developers for their continued work to maintain and enhance OHDSI open-source software. For more information on these or future releases, please visit this thread on the OHDSI forums.


The 2023 OHDSI Global Symposium will be held Oct. 20-22 at the NEW location of the Hilton East Brunswick Hotel & Executive Meeting Center in East Brunswick, N.J. Registration has opened, and the call for collaboration is open until Friday, June 16, at 8 pm ET. Check out the symposium homepage for more information and updates as we get closer to the OHDSI symposium. Please make sure you secure your hotel room by using this link: Available Rooms – Hilton East Brunswick Hotel & Executive Meeting Center

The 2023 European Symposium — titled “Full Steam Ahead” — will be held July 1-3 in Rotterdam. The main conference will be held Monday, July 3, while there will be tutorials on the weekend of July 1-2. Registration and the call for participation has opened for this event. The deadline for abstracts is April 30.

The 2023 Asia-Pacific (APAC) Symposium will be held July 13-14 at the University of New South Wales in Sydney, Australia, and it will follow MedInfo 2023 (July 8-12 in Sydney, Australia). Registration and the call for participation has opened for this event. The call for participation deadline for abstracts is April 15. The agenda is now posted on the event homepage. The main conference will be held July 13 with sessions focused on OHDSI Global, Research, and OHDSI APAC, while there will be tutorials held on July 14.


Ajit Londhe shared a recent forum post announcing a position for Senior Associate Director, Real World Data & Analytics at Boehringer Ingelheim. The purpose of this position is to: generate real world evidence (RWE) to support in-line and pipeline products; provide statistical advice on the analysis of real world data (RWD) to various internal and external stakeholders; contribute to the RWD acquisition strategy and tool evaluation; and participate in the development and presentation of RWE trainings. More information and an application link are available here.

• Dina Gifkins also posted an opening on the forums for the position of Associate Director, Epidemiology, at Janssen Research & Development. Among the primary responsibilities would be to: assist with identifying research study needs, drafting proposals and protocols, and contributing to epidemiology and real world data strategy and study conduct across the clinical development program; conduct literature reviews and synthesis; provide assistance to clinical teams with study design; and identify and evaluate data resources to meet therapeutic needs; and work closely with other colleagues in the Epidemiology department when defining research questions, developing epidemiological protocols, and implementing solutions. More information and an application link are available here.

• Justin Starren announced that the Successful Clinical Response In Pneumonia Therapy (SCRIPT) Systems Biology Center (SCRIPT) is hiring a postdoctoral fellow to work at the intersection of systems biology and clinical data management. The fellow will collaborate with an interdisciplinary team of clinicians, biologists, geneticists, and data scientists to develop tools to improve the management of multifaceted data to support systems biology research. Candidates should have strong software development skills and an MD or PhD with research experience with Electronic Health Record data. Experience with Common Data Models, such as OMOP CDM from OHDSI, is preferred. More information is available here.

• Andrew Williams announced an opening for a Software Developer Analyst II at the Tufts Clinical and Translational Science Institute (CTSI). This position will be responsible for executing software development initiatives, including collaborating with various stakeholders to understand requirements and design solutions, evaluating options and developing technical designs, and developing solution using appropriate programming language and/or technical tools.

• Noémie Elhadad shared that the Columbia University Department of Biomedical Informatics (DBMI) is seeking exceptional junior-level faculty members in the tenure track. The positions are open to researchers interested in developing and applying informatics theory and achieving tangible benefits to health care and biology. Three particular foci are (1) machine learning for healthcare and health-related data science, (2) health information technology-based interventions to improve health care and the health of individuals and populations, and (3) translational bioinformatics. DBMI serves as the coordinating center for OHDSI; more information and an application link are posted here.

• The Observational Health Data Analytics (OHDA) team at Janssen Research & Development recently opened up five new internships for the coming summer, with each lasting at least 10 weeks and starting around the middle of May. There are openings for an epidemiology graduate interna graduate intern, and an undergraduate intern; check out the respective links for more information and an application link. Janssen also announced two summer internships for a Data Science RWE for R&D position, and a Data Science RWE DevCon position.

• The Center for Computational Life Sciences at Cleveland Clinic offers an opportunity for a visionary Senior Faculty to establish our biomedical research and healthcare system as a global leader in Artificial Intelligence Research (AI). This Senior Faculty position will shape and expand AI technologies and applications centered around biomedical science and healthcare, supported by strong institutional commitment to build their vision. More information is available here.


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