Zhong Yuan, MD, PhD
My name is Zhong (pronounced as June), a physician by training and an epidemiologist. I have more than 10 years of experience in academic research (previously affiliated with Medical Colleague of Wisconsin, Milwaukee, WI and Case Western Reserve University of Cleveland, OH), and nearly 18 years of experience in pharmaceutical industry. As part of Clinical Development Program (CDP) at Merck, I provided statistical leadership in the design, conduct, analysis, and reporting of late phase clinical trials. Subsequently after joining Johnson & Johnson in 2005, I provided statistical and epidemiological expertise and leadership in drug development programs through late phase clinical trials and postmarketing safety studies, particularly in the therapeutic areas of Urology, Cardiovascular and Metabolism. I have also quite extensive experience in the area of benefit-risk assessment and framework (both within Janssen Research & Development and some involvement outside the company) and provided critical support to several Advisory Committee meetings. I have authored and co-authored more than 60 peer-reviewed publications.
Yuan Z, DeFalco FJ, Ryan PB, Schuemie MJ, Stang PE, Berlin JA, Desai M, Rosenthal N. Risk of Lower Extremity Amputations in Patients With Type 2 Diabetes Mellitus Treated With SGLT2 Inhibitors in the United States: A Retrospective Cohort Study. Diabetes Obes Metab. 2017 Sep 12. doi: 10.1111/dom.13115. [Epub ahead of print]
Yuan Z, Voss EA, DeFalco FJ; Pan G, Ryan PB, Yannicelli D, Nessel C. Risk Prediction for Ischemic Stroke and Transient Ischemic Attack in Patients without Atrial Fibrillation: A Retrospective Cohort Study. J Stroke Cerebrovasc Dis. 2017 Apr 6. pii: S1052-3057(17)30151-9. doi: 10.1016/j.jstrokecerebrovasdis.2017.03.036. [Epub ahead of print]
Wang Y, Desai M, Ryan PB, DeFalco FJ, Schuemie MJ, Stang PE, Berlin JA, Yuan Z. Incidence of Diabetic Ketoacidosis among Patients with Type 2 Diabetes Mellitus Treated with SGLT2 Inhibitors and Other Antihyperglycemic Agents. Diabetes Research and Clinical Practice 2017; 128: 83-90.