Takashi Moriya, PhD, MBA

BioRelated/Noteworthy Publications

Takashi Moriya, PhD, MBA
Director, Data Sciences
Janssen Pharmaceutical (Japan), Research & Development

Takashi is a director of Data Sciences, a newly established department, in Janssen Japan R&D Division since June, 2019. His professional experiences range from Discovery Research, Clinical Development to Medical Affairs in Liver, Diabetes, Cardiovascular/Metabolic, Infection, Hematology, and other diseases. He also has extensive experience in Clinical Statistics and IT system/database/software development during his 19-years of pharma industry career (Pfizer, RaQualia, Eli Lilly, Gilead, and Chugai/Roche) after graduating from Duke University in Chemistry and Toxicology (2000). He holds a Ph.D. degree (2012) in NASH research from Nagoya University’s Medical School and an Executive MBA degree (2018) from Keio Business School while he worked full-time.

• Moriya T, et al.
Simultaneous changes in high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis and those underlying molecular mechanisms in novel SHRSP5/Dmcr rat. Environmental Health and Preventative Medicine. 2012 Feb 15. doi: 10.1007/s12199-012-0273-y. [Epub ahead of print].
• Kitamori K, Naito H, Tamada H, Kobayashi M, Miyazawa D, Yasui Y, Sonoda K, Tsuchikura S, Yasui N, Ikeda K, Moriya T, et al.
Development of novel rat model for high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis progression in SHRSP5/Dmcr. Environmental Health and Preventative Medicine. 2011 Aug 19. doi: 10.1007/s12199-011-0235-9. [Epub ahead of print].
• Togo K, Matsuoka N, Hashigaki S, Imai K, and Moriya T.
Clinically important effect in new drug development.
Drug Information Journal. 2011;45(6):805-810.
• Moriya T, et al.
Current issues and opportunities of the surrogate endpoint – the perspectives from pharmaceutical industry. Medicine and Drug Journal. 2011;47(3):947-951. (In Japanese)
• Moriya T, et al.
“Hypothesis of seven balances”: molecular mechanisms behind alcoholic liver diseases and association with PPARα. Journal of Occupational Health. 2009;51(5):391-403.
• Sakiyama Y, Yuki H, Moriya T, et al.
Predicting human liver microsomal stability with machine learning techniques.
Journal of Molecular Graphics and Modeling. 2008;26(6):907-915.
• Moriya T, et al.
Toxicities of endocrine-disrupting chemicals, Di(2-ethylhexyl) phthalate (DEHP), via PPAR.
Journal of Clinical and Experimental Medicine. 2007;220(1):125-130. (In Japanese)
Books (co-authored):
• Moriya T, et al.
Chapter 1 – 1 x 1 Factorial Experiment with Qualitative Variable;
Chapter 2 – 1 x 1 Factorial Experiment with Quantitative Variabe;
Chapter 3 – Randomized Block Design;
Chapter 4 – Analysis of Variance; and
Chapter 5 – 2 x 2 Factorial Experiments.
In Haga T, editor. Statistics for Pharmaceutical Drug Development, Part 2 – Experimental Designs. Tokyo: Scientist, Ltd; 2010. pp.13-185. (In Japanese)

医薬品開発のための統計解析 -第2部 実験計画法- 改訂版

• Moriya T, et al.
Chapter 1 – Basics in Statistics;
Chapter 2 – Data Analysis with One Variable;
Chapter 3 – Data Analysis with Two Variables; and
Chapter 4 – Correlation and Regression.
In Haga T, editor. Statistics for Pharmaceutical Drug Development, Part 1 – Basics. Tokyo: Scientist, Ltd; 2009. pp.7-221. (In Japanese)

医薬品開発のための統計解析 -第1部 基礎- 改訂版