Philip R.O. Payne

BioRelated/Noteworthy Publications

Philip R.O. Payne, PhD, FACMI
Robert J. Terry Professor
Founding Director, Institute for Informatics
Washington University

Dr. Payne is the founding Director of the Institute for Informatics (I2) at Washington University in St. Louis, where he also serves as the Robert J. Terry Professor in the School of Medicine. He holds additional appointments as a Professor in the Division of General Medical Science in the Department of Medicine within the School of Medicine and as a Professor of Computer Science and Engineering within the School of Engineering and Applied Science. Previously, Dr. Payne was Professor and Chair of the Department of Biomedical Informatics at The Ohio State University. Dr. Payne is an internationally recognized leader in the field of clinical research informatics (CRI) and translational bioinformatics (TBI). His research portfolio is actively supported by a combination of NCATS, NLM, and NCI grants and contracts, as well a variety of awards from both non-profit and philanthropic organizations. Dr. Payne received his Ph.D. with distinction in Biomedical Informatics from Columbia University, where his research focused on the use of knowledge engineering and human-computer interaction design principles in order to improve the efficiency of multi-site clinical and translational research programs. Prior to pursuing his graduate training, Dr. Payne served in a number of technical and leadership roles at both the UCSD Shiley Eye Center and UCSD Moores Cancer Center. Dr. Payne’s leadership in clinical research informatics community has been recognized through his appointment to numerous national steering, scientific, editorial, and advisory committees, including efforts associated with the American Medical Informatics Association (AMIA), AcademyHealth, the Association for Computing Machinery (ACM), the National Cancer Institute (NCI), the National Library of Medicine (NLM), and the CTSA consortium, as well as his engagement as a consultant to academic health centers throughout the United States and the Institute of Medicine. Dr. Payne is the author of over 190 publications focusing on the intersection of biomedical informatics and the clinical and translational science domains, including several seminal reports that have served to define a new sub-domain of biomedical informatics theory and practice specifically focusing upon clinical research applications. His current research interests include:

  • Knowledge-based approaches to the discovery and analysis of bio-molecular and clinical phenotypes and the ensuing identification of precision diagnostic and therapeutic strategies in cancer;
  • Interventional approaches to the use of electronic health records in order to address modifiable risk factors for disease and enable patient-centered decision making;
  • The study of human factors and workflow issues surrounding the optimal use of healthcare information technology; and,
  • The design and evaluation of open-science platforms that enable collaborative and cumulative approaches to biomedical data analytics.

Embi PJ, Payne PR. Evidence Generating Medicine: Redefining the Research-Practice Relationship to Complete the Evidence Cycle. MedCare. 2013; 51(8):S87-S91

Hersh WR, Weiner MG, Embi PJ, Logan JR, Payne PR, Bernstam EV, Lehmann HP, Hripcsak G, Hartzog TH, Cimino JJ, and Saltz JH. Caveats for the Use of Operational Electronic Health Record Data in Comparative Effectiveness Research. Med Care. 2013; 51(8) suppl 3. PMID:23774517

Embi PJ, Hebert C, Gordillo G, Kelleher K, Payne PR. Knowledge Management and Informatics Considerations for Comparative Effectiveness Research: A Case-driven Exploration. Medical Care. 2013; 51(8):S38-S44.Payne

PR, Marsh CB. Towards a “4I” Approach to Personalized Healthcare. Clin Transl Med. 2012 Jul 30; 1(1); 14. PMC3560982

Payne PR, Embi PJ, Kahn MG. Clinical Research Informatics: The Maturing of a Translational Biomedical Informatics Sub-Discipline. Journal of Biomedical Informatics (JBI). 2011; 4(Suppl 1):S54-5.