Charles Bailey

BioRelated/Noteworthy Publications

Charles Bailey, MD, PhD
Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Children’s Hospital of Philadelphia

Charles Bailey is a pediatric oncologist and clinical informatician at the Children’s Hospital of Philadelphia. His informatics work is grounded in the proposition that the quality of pediatric health care, and the overall health of children, can be improved by intelligent use of clinical and research information. His particular focus is on overcoming barriers to use of electronic health records and similar clinical data as building blocks of a pediatric learning health care system. Currently, their use is limited by technical factors such as differences in data models and the lack of pathways to securely retrieve and analyze data, and cultural factors, such as new ways in which clinicians and health systems interact with electronic health records.

Dr. Bailey serves as the lead investigator for the Data Coordinating Center of PEDSnet, a collaboration across pediatric academic centers to provide a standardized model for clinical data that are accessible for observational research and clinical trials as part of the PCORnet national research network. Other work includes development of pediatric quality measures using electronic records and using clinical data to improve outcomes for children with complex diseases. In each of these areas, understanding the characteristics of clinical information and improving the interoperability of data are critical steps in reaching valid conclusions.

Bailey LC, Forrest CB, Zhang P, et al. Association of antibiotics in infancy with early childhood obesity. JAMA Pediatr. 2014 Nov;168(11):1063-9. doi: 10.1001/jamapediatrics.2014.1539.

Bailey LC, Mistry KB, Tinoco A, et al. Addressing electronic clinical information in the construction of quality measures. Acad Pediatr. 2014 Sep-Oct;14(5 Suppl):S82-9. doi: 10.1016/j.acap.2014.06.006.

Gidengil C, Mangione-Smith R, Bailey LC, et al. Using Medicaid and CHIP claims data to support pediatric quality measurement: lessons from 3 centers of excellence in measure development. Acad Pediatr. 2014 Sep-Oct;14(5 Suppl):S76-81. doi: 10.1016/j.acap.2014.06.014.

Forrest CB, Crandall WV, Bailey LC, et al. Effectiveness of Anti-TNFalpha for Crohn Disease: Research in a Pediatric Learning Health System. Pediatrics. 2014 Jul;134(1):37-44. doi: 10.1542/peds.2013-4103. Epub 2014 Jun 16.

Forrest CB, Margolis PA, Bailey LC, et al. PEDSnet: a National Pediatric Learning Health System. J Am Med Inform Assoc. 2014 Jul-Aug;21(4):602-6. doi: 10.1136/amiajnl-2014-002743. Epub 2014 May 12.

Kahn MG, Bailey LC, Forrest CB, Padula MA, Hirschfeld S. Building a common pediatric research terminology for accelerating child health research. Pediatrics. 2014 Mar;133(3):516-25. doi: 10.1542/peds.2013-1504. Epub 2014 Feb 17.

Seif AE, Fisher BT, Li Y, et al. Patient and hospital factors associated with induction mortality in acute lymphoblastic leukemia. Pediatr Blood Cancer. 2014 May;61(5):846-52. doi: 10.1002/pbc.24855. Epub 2013 Nov 19.

Fisher BT, Harris T, Torp K, et al. Establishment of an 11-year cohort of 8733 pediatric patients hospitalized at United States free-standing children’s hospitals with de novo acute lymphoblastic leukemia from health care administrative data. Med Care. 2014 Jan;52(1):e1-6. doi: 10.1097/MLR.0b013e31824deff9.

Bailey LC, Milov DE, Kelleher K, et al. Multi-Institutional Sharing of Electronic Health Record Data to Assess Childhood Obesity. PLoS One. 2013 Jun 18;8(6):e66192. Print 2013.

Forrest CB, Fiks AG, Bailey LC, et al. Improving adherence to otitis media guidelines with clinical decision support and physician feedback. Pediatrics. 2013 Apr;131(4):e1071-81. doi: 10.542/peds.2012-1988. Epub 2013 Mar 11.