The May 17 OHDSI Community Call brought back a popular format, the OHDSI Debates. We hosted two debates and had the community vote on the winner!

Debate 1: Phenotype Development: One-size-fits-all vs. Tailored-per-databases

Debaters: Azza Shoaibi (Associate Director, Janssen Research & Development) and Asieh Golozar (VP, Global Head of Data Science, Odysseus Data Services, Inc.)

Debate 2: Study Diagnostics: Nice-to-have vs. Essential requirements

Debaters: Dani Prieto-Alhambra (Professor, Univ. of Oxford and Erasmus Univ.) and Martijn Schuemie (Research Fellow, Epidemiology Analytics, Janssen Research & Development

Community Updates

• Congratulations to the team of Justin Reese, Ben Coleman, Lauren Chan, Hannah Blau, Tiffany J. Callahan, Luca Cappelletti, Tommaso Fontana, Katie R. Bradwell, Nomi L. Harris, Elena Casiraghi, Giorgio Valentini, Guy Karlebach, Rachel Deer, Julie A. McMurry, Melissa A. Haendel, Christopher G. Chute, Emily Pfaff, Richard Moffitt, Heidi Spratt, Jasvinder A. Singh, Christopher J. Mungall, Andrew E. Williams & Peter N. Robinson on the publication of NSAID use and clinical outcomes in COVID-19 patients: a 38-center retrospective cohort study in Virology Journal.

• Congratulations to the team of Edward Burn, Talita Duarte-Salles, Sergio Fernandez-Bertolin, Carlen Reyes, Kristin Kostka, Antonella Delmestri, Peter Rijnbeek, Katia Verhamme, and Daniel Prieto-Alhambra on the publication of Venous or arterial thrombosis and deaths among COVID-19 cases: a European network cohort study in The Lancet Infectious Diseases.

• The next CDM Workshop will be held inside MS Teams this Thursday, May 19 (1 pm ET), and it will focus on ETL Vocabulary Mapping. If you are interested in taking part, please fill out this form.

• The Roux Institute will host a one-day Symposium on Risks and Opportunities of AI in Clinical Drug Development on June 6. The event will be held in Portland, Maine, though you can attend this event virtually as well. The event, sponsored by Pfizer Inc., Northeastern University, the American Statistical Association (ASA), the Statistics Department and Data Science Institute at Columbia University, and OHDSI, is designed to serve as a platform for distinguished statisticians, data scientists, regulators, and other professionals to address the challenges and opportunities of AI in pharmaceutical medicine; to foster collaboration among industry, academia, regulatory agencies, and professional associations; and to propose recommendations with policy implications for proper implementation of AI in promoting public health.

• EHDEN is now hosting its sixth open call for data partners looking to map their patient data to the OMOP CDM. Through its first five open calls, EHDEN has created a federated data network of 140 partners across 26 countries, and it has also trained and certified 47 SMEs to assist with mapping this data. Data Partners can benefit from up to a maximum of €100 000 funding. The deadline to apply is June 14, 2022.

• All the talks and workshops from DevCon 2022 have now been uploaded to the DevCon homepage on OHDSI.org.

• Want to help provide the foundation for future advances in OHDSI global research, and receive some benefits for your company in return? Check out the OHDSI Sponsorship homepage, which includes the community call presentation from George Hripcsak.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase

Oct. 15 – Tutorial: Information | Registration

Oct. 15-16 – Workgroup Activities: Information | Registration

2022 OHDSI European Symposium

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Video Presentations

Debate 1: Phenotype Development: One-size-fits-all vs. Tailored-per-databases (Shoaibi vs. Golozar)

Debate 2: Study Diagnostics: Nice-to-have vs. Essential requirements (Schuemie vs. Prieto-Alhambra)

The May 10 Community Call featured three Mother’s Day-themed conversations, facilitated by members of our community. There were discussions around clinical research opportunities, community building and data standards, and they were meant to be open conversations to address challenges within our community and/or the healthcare field.

The three discussions (all of which are posted below) and facilitators were:

Clinical Research Opportunities: Brainstorm on maternal health
– Alison Callahan, Research Scientist, Stanford Center for Biomedical Informatics
 – Ru-fong Cheng, Senior Medical Director, Women’s Health, Office of the Chief Medical Officer, Johnson & Johnson
 – Noémie Elhadad, Associate Professor of Biomedical Informatics; Vice Chair, Research, Columbia Department of Biomedical Informatics

How can OHDSI support collaborator mothers to advance their personal and professional development?
– Rupa Makadia, Associate Director, Epidemiology Analytics, Janssen Research and Development
 – Sarah Seager, Director of Data Science, OMOP at IQVIA

Recommended best practices for modeling pregnancy episodes and mother-child linkage
– Jill Hardin, Associate Director, Epidemiology Analytics, Janssen Research and Development
 – Mui Van Zandt, VP & GM Real World Data & Tech, IQVIA 

Community Updates

• Congratulations to the team of Fatemeh Amrollahi, Supreeth P Shashikumar, Angela Meier, Lucila Ohno-Machado, Shamim Nemati, and Gabriel Wardi on the publication of Inclusion of social determinants of health improves sepsis readmission prediction models in JAMIA.

• Registration is now open for workgroup activities and meetings during the weekend of the 2022 OHDSI Global Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. Check out this page for descriptions and times of all meetings, and then register for any meetings you would like to join (these meetings are free, but registration is important because this will be first-come, first-served due to room capacity).

• All the talks and workshops from DevCon 2022 have now been uploaded to the DevCon homepage on OHDSI.org.

• Last week’s APAC Community Call included a presentation from Gowtham Rao on how to take advantage of the cohort diagnostics tool using one of the ongoing APAC studies as an example. You can find the recording on the APAC Community page.

• It was also announced on the last APAC call that the 2022 OHDSI APAC Symposium will be held Nov. 12-13 in Taipei, Taiwan. There will be both an on-site and virtual component to this event. Please follow the APAC Community page for more information.

• The latest OHDSI newsletter is now available, and it includes all the key information from DevCon, links to 10 community publications from April, details on the Sponsorship Program and other updates. If you don’t receive the monthly newsletter, you can subscribe to it here.

• Are you running a network study and seeking collaboration or data partners? Our May 24 community call will be focused on Open Studies, and we are looking for presenters. If you would like to join this call, please contact Craig Sachson at sachson@ohdsi.org.

• Want to help provide the foundation for future advances in OHDSI global research, and receive some benefits for your company in return? Check out the OHDSI Sponsorship homepage, which includes the community call presentation from George Hripcsak.

Openings

• Dani Prieto-Alhambra and his team at Oxford are recruiting a Database Programmer to join the team. This position will contribute to the standardization and curation of large real world data from the UK and collaborate with the OHDSI, EHDEN and OPTIMA Oncology teams. More information and the application link are available here. The application deadline is May 23, 2022.

• Peter Reinbeek and the Erasmus Medical Center team shared an opening for an R Programmer in Health Data Science. This position will be responsible for designing, developing, documenting, and maintaining R code that will be executed against health data that is standardized to the OMOP Common Data Model. More information and the application link are available here.

• As mentioned by Sally Baxter and Kerry Goetz during a recent community call, the National Eye Institute is looking for a DATA Scholar to develop a strategy and lead community consensus building to improve ocular health care through data standardization. Among other responsibilities, this person will build on community expertise of the OMOP CDM to advance standard representation of ocular concepts. More information is available here.

• Cynthia Sung shared a recent summer internship opportunity in the Bill & Melinda Gates Medical Research Institute. One internship of potential interest to the community is seeking a candidate in the areas of computational biology, computer science or bioengineering major who is proficient in coding in SQL and R or Python to transform Tuberculosis clinical trial data into the OMOP CDM. More information and an application link are available here.

• Daniel Smith shared a recent opening at Emory University in Atlanta for an Informatics Analyst; this position will provide OMOP support for Winship Data and Winship Discovery projects. You can learn more about this project and apply here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

Oct. 15-16 — Workshop Activities: Information | Registration

2022 OHDSI European Symposium

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

Community Updates

Video Presentations

Clinical Research Opportunities: Brainstorm on maternal health (Alison Callahan, Ru-fong Cheng, Noémie Elhadad)

How can OHDSI support collaborator mothers to advance their personal/professional development? (Rupa Makadia, Sarah Seager)

Recommended best practices for modeling pregnancy episodes and mother-child linkage (Jill Hardin, Mui Van Zandt)

The May 3 Community Call focused on the DARWIN EU Initiative, as well as how the OHDSI community can impact this new push towards using real-world evidence to impact healthcare.

The vision of DARWIN EU is to give the European Medicines Agency and national competent authorities in EU Member States access to valid and trustworthy real-world evidence, for example on diseases, patient populations, and the use, safety and effectiveness of medicines, including vaccines, throughout the lifecycle of a medicinal product.

The Erasmus Medical Center has earned the contract as the coordinating center for DARWIN EU. Peter Rijnbeek, Head of the Department of Medical Informatics at Erasmus Medical Center, led this presentation about the DARWIN EU mission and five-year plan, the role of the coordinating center, and how OHDSI tools and standards can and will impact this initiative.

Community Updates

• Congratulations to the team of Anna Ostropolets, Xintong Li, Rupa Makadia, Gowtham Rao, Peter Rijnbeek, Talita Duarte-Salles, Anthony Sena, Azza Shaoibi, Marc Suchard, Patrick Ryan, Daniel Prieto-Alhambra and George Hripcsak on the publication of Factors Influencing Background Incidence Rate Calculation: Systematic Empirical Evaluation Across an International Network of Observational Databases in Frontiers of Pharmacology.

• Congratulations to the team of Juan Quiroz, Tim Chard, Zhisheng Sa, Angus Ritchie, Louisa Jorm and Blanca Gallego on the publication of Extract, transform, load framework for the conversion of health databases to OMOP in PLOS One.

• All the talks and workshops from DevCon 2022 have now been uploaded to the DevCon homepage on OHDSI.org. A big announcement from DevCon was the formation of the Khieron Contributor Cohort, which will help onboard and mentor open-source developers in the community. If you are interested in joining the effort, please fill out this application; the deadline is THIS FRIDAY, May 6.

• This week’s APAC Community Call (May 5 in the Eastern Hemisphere, May 4 in the Western Hemisphere) will include a presentation from Gowtham Rao, who will present how to take advantage of the cohort diagnostics tool using one of the ongoing APAC studies as an example. You can get the call invitation by joining the APAC Workgroup, or you can find the link or access the recording afterwards on the APAC Community page.

• The latest OHDSI newsletter is now available, and it includes all the key information from DevCon, links to 10 community publications from April, details on the Sponsorship Program and other updates. If you don’t receive the monthly newsletter, you can subscribe to it here.

• Are you running a network study and seeking collaboration or data partners? Our May 24 community call will be focused on Open Studies, and we are looking for presenters. If you would like to join this call, please contact Craig Sachson at sachson@ohdsi.org.

• Want to help provide the foundation for future advances in OHDSI global research, and receive some benefits for your company in return? Check out the OHDSI Sponsorship homepage, which includes the community call presentation from George Hripcsak.

Openings

• Dani Prieto-Alhambra and his team at Oxford are recruiting a Database Programmer to join the team. This position will contribute to the standardization and curation of large real world data from the UK and collaborate with the OHDSI, EHDEN and OPTIMA Oncology teams. More information and the application link are available here. The application deadline is May 23, 2022.

• Peter Reinbeek and the Erasmus Medical Center team shared an opening for an R Programmer in Health Data Science. This position will be responsible for designing, developing, documenting, and maintaining R code that will be executed against health data that is standardized to the OMOP Common Data Model. More information and the application link are available here.

• As mentioned by Sally Baxter and Kerry Goetz during a recent community call, the National Eye Institute is looking for a DATA Scholar to develop a strategy and lead community consensus building to improve ocular health care through data standardization. Among other responsibilities, this person will build on community expertise of the OMOP CDM to advance standard representation of ocular concepts. More information is available here.

• Cynthia Sung shared a recent summer internship opportunity in the Bill & Melinda Gates Medical Research Institute. One internship of potential interest to the community is seeking a candidate in the areas of computational biology, computer science or bioengineering major who is proficient in coding in SQL and R or Python to transform Tuberculosis clinical trial data into the OMOP CDM. More information and an application link are available here.

• Daniel Smith shared a recent opening at Emory University in Atlanta for an Informatics Analyst; this position will provide OMOP support for Winship Data and Winship Discovery projects. You can learn more about this project and apply here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

2022 OHDSI European Symposium

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

Community Updates

Video Presentation

The April 26 Community Call, focused on the state of the OHDSI open-source community, and it included a recap on the first OHDSI DevCon, held April 22. We also heard about a new opportunity in open-source development that was announced during the State of the Community presentation (more on this below).

We heard from the following leaders in our open-source community:

• Lee Evans (Owner • LTS Computing LLC) 
• Martijn Schuemie (Research Fellow, Epidemiology Analytics • Janssen Research and Development)
• Paul Nagy (Associate Professor • Johns Hopkins School of Medicine)
• Adam Black (Data Sciences • Odysseus Data Services)

Community Updates

• Congratulations to the team of Yilu Fang, Betina Idnay, Yingcheng Sun, Hao Liu, Zhehuan Chen, Karen Marder, Hua Xu, Rebecca Schnall, and Chunhua Weng on the publication of Combining human and machine intelligence for clinical trial eligibility querying in JAMIA.

• Congratulations to the team of Katie Bradwell, Jacob Wooldridge, Benjamin Amor, Tellen Bennett, Adit Anand, Carolyn Bremer, Yun Jae Yoo, Zhenglong Qian, Steven Johnson, Emily Pfaff, Andrew Girvin, Amin Manna, Emily Niehaus, Stephanie Hong, Xiaohan Tanner Zhang, Richard Zhu, Mark Bissell, Nabeel Qureshi, Joel Saltz, Melissa Haendel, Christopher Chute, Harold Lehmann, and Richard Moffitt (on behalf of the N3C Consortium) on the publication of Harmonizing units and values of quantitative data elements in a very large nationally pooled electronic health record (EHR) dataset in JAMIA.

• Congratulations to the team of Kristina Bardenheuer, Michel Van Speybroeck, Clare Hague, Enkeleida Nikai, and Martin Price on the publication of Haematology Outcomes Network in Europe (HONEUR) – a collaborative, interdisciplinary platform to harness the potential of Real-World Data in hematology in the European Journal of Haematology.

• OHDSI DevCon 2022 was a success last Friday, with more than 100 people joining for a series of workshops, talks and an impressive final panel discussion. All the talks will be loaded to the DevCon homepage on OHDSI.org, but both the State of the Community presentation by Adam Black and Paul Nagy, as well as the Keynote Address by Martijn Schuemie, are currently on the page. A big announcement from DevCon was the formation of the Khieron Contributor Cohort, which will help onboard and mentor open-source developers in the community. If you are interested in joining the effort, please fill out this application.

• Want to help provide the foundation for future advances in OHDSI global research, and receive some benefits for your company in return? Check out the OHDSI Sponsorship homepage, which includes the community call presentation from George Hripcsak.

• The most recent APAC Community Call featured APAC Studies quarterly updates. You can access the recording afterwards, on the APAC Community page.

• Are you running a network study and seeking collaboration or data partners? Our May 24 community call will be focused on Open Studies, and we are looking for presenters. If you would like to join this call, please contact Craig Sachson at sachson@ohdsi.org.

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs
Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Openings

• Peter Reinbeek and the Erasmus Medical Center team shared an opening for an R Programmer in Health Data Science. This position will be responsible for designing, developing, documenting, and maintaining R code that will be executed against health data that is standardized to the OMOP Common Data Model. More information and the application link are available here. The application deadline is this Wednesday, April 27.

• Dani Prieto-Alhambra and his team at Oxford are recruiting a Database Programmer to join the team. This position will contribute to the standardization and curation of large real world data from the UK and collaborate with the OHDSI, EHDEN and OPTIMA Oncology teams. More information and the application link are available here. The application deadline is May 23, 2022.

• As mentioned by Sally Baxter and Kerry Goetz on last week’s community call, the National Eye Institute is looking for a DATA Scholar to develop a strategy and lead community consensus building to improve ocular health care through data standardization. Among other responsibilities, this person will build on community expertise of the OMOP CDM to advance standard representation of ocular concepts. More information is available here.

Slides

Community Updates

Video Presentation

The April 19 OHDSI Community Call featured a new set of workgroup updates, including an introduction of a brand new workgroup (Eye Care and Vision Research):

• Eye Care and Vision Research (Sally Baxter, Assistant Professor, Division Chief for Ophthalmology Informatics and Data Science, UC San Diego)
• FHIR and OMOP (Christian Reich, Vice President, RWE Systems • IQVIA)
• Oncology (Asieh Golozar, VP, Global Head of Data Science • Odysseus Data Services)
• Steering Group (Jody-Ann McLeggon • Program Manager, Columbia University)

Community Updates

• Congratulations to the team of Henrik John, Jan Kors, Jenna Reps, Patrick Ryan, and Peter Rijnbeek on the publication of Logistic regression models for patient-level prediction based on massive observational data: Do we need all data? in the International Journal of Medical Informatics.

• Congratulations to the team of Yilu Fang, Betina Idnay, Yingcheng Sun, Hao Liu, Zhehuan Chen, Karen Marder, Hua Xu, Rebecca Schnall, and Chunhua Weng on the publication of Combining human and machine intelligence for clinical trial eligibility querying in JAMIA.

• Curious about the new OHDSI Sponsorship program that was announced last week, and how you can help support the community’s global research journey? Check out the OHDSI Sponshorship homepage, which includes the community call presentation from George Hripcsak.

• The next APAC Community Call will be held Thursday, April 21 (Wednesday night in the Western Hemisphere) and will provide APAC Studies quarterly updates. You can get the link for the call, or access the recording afterwards, on the APAC Community page.

• Are you running a network study and seeking collaboration or data partners? Our May 24 community call will be focused on Open Studies, and we are looking for presenters. If you would like to join this call, please contact Craig Sachson at sachson@ohdsi.org.

• The Open-Source Community is hosting the first OHDSI Dev Con on April 22 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. You can register for the event now. 

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs
Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

Eye Care & Vision Research | FHIR & OMOP | Oncology | Steering Group | Community Updates

Videos

Eye Care & Vision Research (Sally Baxter and Kerry Goetz)

FHIR & OMOP (Christian Reich)

Oncology (Asieh Golozar)

Steering Group (Jody-Ann McLeggon)

George Hripcsak, Chair and Vivian Beaumont Allen Professor of Biomedical Informatics at Columbia University, discussed the many ways Columbia DBMI supports OHDSI, and he shares why it will be important to support the coordinating center in the future, as well as what benefits can come from your support. 

Community Updates

• Congratulations to the team of Berta Raventós, Andrea Pistillo, Carlen Reyes, Sergio Fernández-Bertolín, Maria Aragón, Anna Berenguera, Constanza Jacques-Aviñó, Laura Medina-Perucha, Edward Burn, and Talita Duarte-Salles on the publication of Impact of the COVID-19 pandemic on diagnoses of common mental health disorders in adults in Catalonia, Spain: a population-based cohort study in BMJ Open.

• Congratulations to the team of Tae-Hoon Kim, SiHyeong Noh, Youe Ree Kim, ChungSub Lee, Ji Eon Kim, Chang-Won Jeong, and Kwon-Ha Yoon on the publication of Development and validation of a management system and dataset quality assessment tool for the Radiology Common Data Model (R_CDM): A case study in liver disease in the International Journal of Medical Informatics.

• Based on George Hripcsak’s presentation, OHDSI has created both Sponsorship Program and Sponsors pages on the website. Please check them out and see how you can support OHDSI’s growth while receiving several benefits for your organization.

• The Open-Source Community is hosting the first OHDSI Dev Con on April 22 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. You can register for the event now.

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs
Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

OHDSI Coordinating Center | Community Updates

Video

Patrick Ryan led the OHDSI community in a game of “Name That Result” (a distant relative of the old Name That Tune game show) where eight contestants were able to showcase all the ways they could get from data to evidence using the OMOP CDM and OHDSI tools. This one was decided on the final question!

Thank you to Michael Cook, Stephanie Hong, Kristin Kostka, Martin Lavallee, Filip Malkovic, Maxim Moinat, Jose Posada, and Katherine Simon for their insights and spirited competition in this game!

Community Updates

• Congratulations to the team of Chongliang Luo, Md Nazmul Islam, Natalie Sheils, John Buresh, Jenna Reps, Martijn Schuemie, Patrick Ryan, Mackenzie Edmondson, Rui Duan, Jiayi Tong, Arielle Marks-Anglin, Jiang Bian, Zhaoyi Chen, Talita Duarte-Salles, Sergio Fernández-Bertolín, Thomas Falconer, Chungsoo Kim, Rae Woong Park, Stephen Pfohl, Nigam Shah, Andrew Williams, Hua Xu, Yujia Zhou, Ebbing Lautenbach, Jalpa Doshi, Rachel Werner, David Asch, and Yong Chen on the publication of DLMM as a lossless one-shot algorithm for collaborative multi-site distributed linear mixed models in Nature Communications.

• Congratulations to the team of Seok Kim, Ji-In Bang, Dachung Boo, Borham Kim, In Young Choi, SooJeong Ko, Ie Ryung Yoo, Kwangsoo Kim, Junmo Kim, YoungHwan Joo, Hyun Gee Ryoo, Jin Chul Paeng, Jung Mi Park, Woncheol Jang, Byungwon Kim, Yangha Chung, Dongyoon Yang, Sooyoung Yoo, and Ho-Young Lee on the publication of Second primary malignancy risk in thyroid cancer and matched patients with and without radioiodine therapy analysis from the observational health data sciences and informatics in European Journal of Nuclear Medicine and Molecular Imaging.

• Both the presentations and slides from the recent community call session on Reproducibility are now available here. This session was led by Anna Ostropolets, Martijn Schemie and Asieh Golozar, and focused on the OHDSI2021 Reproducibility Challenge, how to design reproducible studies, and the Reproducibility Service at the Roux Institute.

• The April edition of the OHDSI Newsletter is now available, and it includes reports on the CDM Workshop, DevCon, and the OHDSI2022 Tutorial, as well as other community updates, links to publications and presentations, and plenty more. If you aren’t already subscribing to the newsletter, you can do so here.

• The Open-Source Community is hosting the first OHDSI Dev Con on April 22 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. You can register for the event now.

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs
Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage. 

Slides

Community Updates

Video

The March 29 OHDSI Community Call focused on reproducibility, and three leaders in the community shared presentations on this topic. 

– The 2021 OHDSI Reproducibility Challenge (Anna Ostropolets)
– Developing Reproducible Studies (Martijn Schuemie)
– The OHDSI Reproducibility Service (Asieh Golozar)

Community Updates

• Congratulations to the team of Yuan Lu, Mui Van Zandt, Yun Liu, Jing Li, Xialin Wang, Yong Chen, Zhengfeng Chen, Jaehyeong Cho, Sreemanee Raaj Dorajoo, Mengling Feng, Min-Huei Hsu, Jason C. Hsu, Usman Iqbal, Jitendra Jonnagaddala, Yu-Chuan Li, Siaw-Teng Liaw, Hong-Seok Lim, Kee Yuan Ngiam, Phung-Anh Nguyen, Rae Woong Park, Nicole Pratt, Christian Reich, Sang Youl Rhee, Selva Muthu Kumaran Sathappan, Seo Jeong Shin, Hui Xing Tan, Seng Chan You, Xin Zhang, Harlan M. Krumholz, Marc A. Suchard, and Hua Xu on the publication of Analysis of Dual Combination Therapies Used in Treatment of Hypertension in a Multinational Cohort in JAMA Network Open.

This is an especially exciting paper, as it is the first to come out of the OHDSI Asia-Pacific (APAC) Workgroup. The APAC team leads a bi-weekly community call, and each is recorded. Last week’s session included a presentation from Christian Reich about the FHIR-OMOP partnership. You can see that recording and get both the link and themes for upcoming calls at the APAC homepage.

• Congratulations to both Aki Nishimura and Marc Suchard on the publication of Prior-preconditioned conjugate gradient method for accelerated Gibbs sampling in ‘large n & large p’ Bayesian sparse regression in the Journal of the American Statistical Association.

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs
Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

• The Open-Source Community is hosting the first OHDSI Dev Con on April 22 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. The full agenda has been added. You can register for the event now.

• The recent presentation on “The OHDSI Vocabulary Journey” from Michael Kallfelz, Christian Reich and Patrick Ryan, including both the video and slides from the community call, as well as the introduction from the Vocabulary chapter in the Book of OHDSI, is available here.

• The OMOP CDM Workshop that was held earlier this month has been put together into a single video tutorial, which you can find here. This page also has all the slides from the workshop, as well as the CDM introductory text from the Book of OHDSI.

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

Reproducibility Challenge | Designing Reproducible Studies | OHDSI Reproducibility Service | Community Updates

Video Presentations

Reproducibility Challenge (Anna Ostropolets)

Designing Reproducible Studies (Martijn Schuemie)

The OHDSI Reproducibility Service (Asieh Golozar)

The March 22 OHDSI Community Call provided an in-depth look at the OHDSI vocabulary, from how it is developed, to how it can be utilized, and where it should grow from here. Three leaders from the vocabulary workgroup joined to present a trio of topics for this session (see below). 

– A peek into the OHDSI vocabulary engine room (Michael Kallfelz)
– Fun things you can learn with the OHDSI standardized vocabularies (Patrick Ryan)
– Time for reflection • Where are we? Where should we be? (Christian Reich)

Community Updates

• Congratulations to the team of JungHyun Byun, Dong Yun Lee, Chang-Won Jeong, Yerim Kim, Hak Young Rhee, Ki Won Moon, Jeongwon Heo, Yoonki Hong, Woo Jin Kim, Seung-Joo Nam, Hoon Sung Choi, Ji In Park, In Kook Chun, So Hyeon Bak, Kyoungyul Lee, Gi Hwan Byeon, Kyoung Lae Kim, Jeong-Ah Kim, Young Joo Park, Jeong Hyun Kim, Eun ju Lee, Sang-Ah Lee, Sung Ok Kwon, Sang-Won Park, Payam Hosseinzadeh Kasani, Jung-Kyeom Kim, Yeshin Kim, Seongheon Kim and Jae-Won Jang on the publication of Analysis of treatment pattern of anti-dementia medications in newly diagnosed Alzheimer’s dementia using OMOP CDM in Scientific Reports.

• Congratulations to the team of Kristin Kostka, Talita Duarte-Salles, Albert Prats-Uribe, Anthony G Sena, Andrea Pistillo, Sara Khalid, Lana YH Lai, Asieh Golozar, Thamir M Alshammari, Dalia M Dawoud, Fredrik Nyberg, Adam B Wilcox, Alan Andryc, Andrew Williams, Anna Ostropolets, Carlos Areia, Chi Young Jung, Christopher A Harle, Christian G Reich, Clair Blacketer, Daniel R Morales, David A Dorr, Edward Burn, Elena Roel, Eng Hooi Tan, Evan Minty, Frank DeFalco, Gabriel de Maeztu, Gigi Lipori, Hiba Alghoul, Hong Zhu, Jason A Thomas, Jiang Bian, Jimyung Park, Jordi Martínez Roldán, Jose D Posada, Juan M Banda, Juan P Horcajada, Julianna Kohler, Karishma Shah, Karthik Natarajan, Kristine E Lynch, Li Liu, Lisa M Schilling, Martina Recalde, Matthew Spotnitz, Mengchun Gong, Michael E Matheny, Neus Valveny, Nicole G Weiskopf, Nigam Shah, Osaid Alser, Paula Casajust, Rae Woong Park, Robert Schuff, Sarah Seager, Scott L DuVall, Seng Chan You, Seokyoung Song, Sergio Fernández-Bertolín, Stephen Fortin, Tanja Magoc, Thomas Falconer, Vignesh Subbian, Vojtech Huser, Waheed-Ul-Rahman Ahmed, William Carter, Yin Guan, Yankuic Galvan, Xing He, Peter R Rijnbeek, George Hripcsak, Patrick B Ryan, Marc A Suchard, and Daniel Prieto-Alhambra on the publication of Unraveling COVID-19: A Large-Scale Characterization of 4.5 Million COVID-19 Cases Using CHARYBDIS in Clinical Epidemiology.

• We are thrilled to announce that registration for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center, is now open!

The main conference will be held Friday, Oct. 14, while a full-day tutorial will be held Saturday, Oct. 15. Other community activities, mainly focused on OHDSI workgroups, will be held both Oct. 15 and Oct. 16. The OHDSI2022 homepage has more information, as well as registration links to both the conference and the tutorial (these are separate events and each requires its own registration), information on the collaborator showcase, hotel room blocks, and plenty more.

Direct registration is available for both the main conference and the full-day tutorial. Please continue to check our symposium homepage and our social platforms, and join the weekly OHDSI community calls, for more information.

• The Open-Source Community is hosting the first OHDSI Dev Con on April 12 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. You can register for the event now.

• The OMOP CDM Workshop that was held over the last two OHDSI Community Calls has been put together into a single video tutorial, which you can find here. This page also has all the slides from the workshop, as well as the CDM introductory text from the Book of OHDSI.

• The next APAC Community Call will be held this Wednesday/Thursday based on your time zone. Christian Reich will present on the OMOP/FHIR collaboration during this call. You can access these calls by joining the Asia-Pacific (APAC) Workgroup in Teams.

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

OHDSI Vocabulary Journey | Community Updates

Video Presentation

Clair Blacketer and members of the CDM Workgroup put together the second of a two-part CDM Workshop session during the March 15 OHDSI Community Call. Following an introduction by Clair, there were specific talks on the following topics:

• Vocabulary Mapping and Usagi (Melanie Philofsky)
• Data Quality (Clair Blacketer)
• ACHILLES (Anthony Molinaro)
• Putting It All Together (Frank DeFalco) 

Part 1 of this workshop was held during the March 8 Community Call; you can watch that video here: https://youtu.be/y7CXONEMLoI.

Community Updates

• Congratulations to the team of Matthew Spotnitz, Anna Ostropolets, Victor G. Castanob, Karthik Natarajan, Genna Waldman, Michael Argenziano, Ruth Ottman, George Hripcsak, Hyunmi Choi, and Brett Youngerman for the publication of Patient characteristics and antiseizure medication pathways in newly diagnosed epilepsy: Feasibility and pilot results using the common data model in a single-center electronic medical record database recently in Epilepsy & Behavior.

• The 2022 OHDSI Symposium will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center in Bethesda, Md. The main symposium will be held Friday, Oct. 14, while the next two weekend will include community activities. More information about the weekend, including registration and the collaborator showcase, will be shared when available.

• The Open-Source Community is hosting the first OHDSI Dev Con on April 12 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. You can register for the event now.

• Phenotype Phebruary may have ended, but the conversations still continue in the OHDSI forums. All of the “phun phacts” that were shared during our community calls have been put together in a single video, so you can learn about all 29 phenotypes discussed during the month. All daily threads can be found on the Phenotype Phebruary homepage.

• Our colleagues within EHDEN are opening their fourth and final call for SMEs to apply for training and certification on converting health data from various formats to the OMOP common data model. Currently, EHDEN has 47 SMEs across 19 European nations working on the EHDEN data network, which includes 140 data partners across 16 countries. You can see the fill list of EHDEN-certified SMEs, as well the EHDEN data partner network.

• Dani Prieto-Alhambra recently shared that his team at Oxford is accepting applications for an IT System Manager and Database Administrator. The deadline for application is April 11, 2022. For more registration and to apply, please visit the Job Details page.

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

CDM Workshop | Community Updates

Video

CDM Workshop (Clair Blacketer, Melanie Philofsky, Anthony Molinaro and Frank DeFalco)

The March 8 OHDSI community call featured Part 1 of our two-week OMOP CDM Workshop. We were excited to have four representatives from our Common Data Model Workgroup lead this session:  

• Clair Blacketer, Associate Director, Janssen Research & Development
• Frank DeFalco, Director, Observational Health Data Analytics, Janssen Research & Development
• Kristin Kostka, Director of the OHDSI Center, Roux Institute, Northeastern University
• Maxim Moinat, Data Engineer/Software Developer, The Hyve

Prior to the CDM Workshop, Paul Nagy presented the newly developed Engine of Impact Project (EOI), a dashboard that allows for regular monitoring of the health and progress of the OHDSI community. Videos/slides for both the CDM Workshop and EOI Project are below.

Community Updates

• The 2022 OHDSI Symposium will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center in Bethesda, Md. The main symposium will be held Friday, Oct. 14, while the next two weekend will include community activities. More information about the weekend, including registration and the collaborator showcase, will be shared when available.

• The latest edition of The Journey newsletter is now available. This edition includes a full review of Phenotype Phebruary, a look at the DARWIN EU announcement by the European Medicines Agency, publications and presentations, and much more. If you don’t get The Journey in your email, please subscribe here.

• 2021 OHDSI Titan Award winner Maxim Moinat was profiled in our latest Collaborator Spotlight. Learn more about Maxim’s background, his work with open-source tools, EHDEN, the upcoming DARWIN EU initiative, and much more.

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• If you missed Nicole Pratt’s CBER BEST Seminar on “Evaluating Use of Methods for Adverse Event Under Surveillance for Vaccines,” you can watch it now.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

CDM Workshop | EOI Project | Community Updates

Videos

CDM Workshop (Clair Blacketer, Frank DeFalco, Kristin Kostka, Maxim Moinat)

Engine of Impact Project (Paul Nagy)

The March 1 OHDSI community call included final reflections on Phenotype Phebruary, and then hosted breakout discussions on what is happening around the three main OHDSI focuses of characterization, estimation and prediction, and how do we as a community collaborate to accomplish our 2022 OKRs. 

• Patrick Ryan will led the final update on Phenotype Phebruary, which you can join in the daily conversations at the OHDSI forums or at the event homepage
• Anthony Sena and Aniek Markus moderated a conversation in work around Characterization
• Marc Suchard moderated a conversation in work around Estimation
• Jenna Reps and Ross Williams moderated a conversation in work around Prediction

Community Updates

• As announced at our last community call, the 2022 OHDSI U.S. Symposium will be held Oct. 14-16, with the main symposium set for Oct. 14. We will have more information on the event in the coming weeks, but please save those dates for #OHDSI2022.

• Phenotype Phebruary completed its final week, and it has been amazing to watch the activity ongoing on so many threads discussing different phenotypes developments & evaluation. Each daily post is linked on this page on OHDSI.org: https://www.ohdsi.org/phenotype-phebruary/. You can find each phenotype topic and post from the last week below; please check them out and continue the conversations. Thank you to Asieh Golozar, Rupa Makadia, Jill Hardin, Erica Voss, Tiffany Callahan, Juan Banda, Anna Ostropolets, Claudia Pulgarin, Marcela Rivera, and David Vizcaya for leading these discussions

Feb. 21 • Prostate Cancer
Feb. 22 • HIV
Feb. 23 • Hidradenitis Suppurativa
Feb. 24 • Anaphylaxis
Feb. 25 • Depression
Feb. 26 • Non-Small-Cell Lung Cancer
Feb. 27 • Drug-Induced Liver Injury
Feb. 28 • Severe Visual Impairment and Blindness
Bonus • Acute Kidney Injury

• Congratulations to the team of Edward Burn, Xintong Li, Kristin Kostka, Henry Morgan Stewart, Christian Reich, Sarah Seager, Talita Duarte-Salles, Sergio Fernandez-Bertolin, María Aragón, Carlen Reyes, Eugenia Martinez-Hernandez, Edelmira Marti, Antonella Delmestri, Katia Verhamme, Peter Rijnbeek, Scott Horban, Daniel Morales, and Daniel Prieto-Alhambra on the recent publication of Background rates of five thrombosis with thrombocytopenia syndromes of special interest for COVID-19 vaccine safety surveillance: Incidence between 2017 and 2019 and patient profiles from 38.6 million people in six European countries in Pharmacoepidemiology and Drug Safety.

• Congratulations to the team of Emily Pfaff, Melissa Haendel, Kristin Kostka, Adam Lee, Emily Niehaus, Matvey Palchuk, Kellie Walters, and Christopher Chute on the recent publication of Ensuring a safe(r) harbor: Excising personally identifiable information from structured electronic health record data in the Journal of Clinical and Translational Science.

• Clair Blacketer led Part 2 of a CDM Workshop for the Asia-Pacific (APAC) community as part of the most recent APAC Community Call (see video here). Clair will lead a two-part workshop on the global community call over the next two weeks.

• Curious about the Objectives & Key Results (OKRs) set by our various workgroups. These were presented at a recent meeting between workgroup leads, and they have been posted to the new OHDSI Workgroups page. If you want to join any of our workgroups, please fill out this form.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The #OHDSISocialShowcase wraps up this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: OMOP-CDM ETLs with Dask and Prefect
Tuesday: Learning under constraints with EXPLORE
Wednesday: Estimating Model Performance on External Datasets from Their Limited Statistical Characteristics: Application to 3-Year Surgery Risk in Ulcerative Colitis

Slides

Phenotype Phebruary Report | Prediction Breakout | Community Updates

Videos

Phenotype Phebruary Final Report (Patrick Ryan)

Characterization Discussion (moderated by Aniek Markus and Anthony Sena)

Estimation Discussion (moderated by Marc Suchard)

Prediction Discussion (moderated by Jenna Reps and Ross Williams)

The Feb. 22 OHDSI community call featured a trio of presentations:

Community Updates

• Phenotype Phebruary is heading into the final week, and we currently have 20 interactive forum threads ongoing discussing different phenotypes developments & evaluation. Each daily post will be linked on this page on OHDSI.org: https://www.ohdsi.org/phenotype-phebruary/. You can find each phenotype topic and post from the last week below; please check them out and continue the conversations. Thank you to Azza Shoaibi, Gowtham Rao, Adam Black and Evan Minty for leading these discussions

Feb. 14 • Hypertension (Video Description)
Feb. 15 • Acute Myocardial Infarction
Feb. 16 • Heart Failure
Feb. 17 • Cardiomyopathy
Feb. 18 • Multiple Sclerosis
Feb. 19 • Triple Negative Breast Cancer
Feb. 20 • Pulmonary Hypertension
Feb. 21 • Prostate Cancer

• The next CBER Best Seminar will be provided by a veteran collaborator within the OHDSI community. Nicole Pratt (Professor, University of South Australia) will present on “Evaluating Use of Methods for Adverse Event Under Surveillance For Vaccines” at 11 am ET this Wednesday, Feb. 23. This seminar is free and open to the public; you can register here.

• The next Asia-Pacific (APAC) Community Call will be held Wednesday, March 23 at 10 pm ET. Clair Blacketer will provide part 2 of the first CDM Workshop of 2022. If you missed the first part, you can watch that recording here.

• Curious about the Objectives & Key Results (OKRs) set by our various workgroups? These were presented at a recent meeting between workgroup leads, and they have been posted to the new OHDSI Workgroups page. If you want to join any of our workgroups, please fill out this form.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage. 

• Our collaborators at Janssen Research & Development recently posted a new position for Manager, Observational Health Data Analytics. You can find a job description and application link here.

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: Attention based deep neural networks in patient level prediction
Tuesday: REDCap2OMOP: A platform for ETLing REDCap projects into the OMOP CDM
Wednesday: Trends in the development and validation of patient-level prediction models using electronic health record data: a systematic review
Thursday: Short-term mortality in patients undergoing colorectal cancer surgery: A prediction study
Friday: Proof-of-concept model targeting patient-level prediction of 90-day mortality after colorectal cancer surgery kickstarts OHDSI journey

Slides

ATLAS WG | Medical Imaging WG | Phenotype Phebruary | Community Updates

Video Presentations

ATLAS WG (Anthony Sena)

Medical Imaging WG (Paul Nagy)

Phenotype Phebruary (Patrick Ryan)

The Feb. 8 OHDSI community call featured a trio of presentations:

Community Updates

• Congratulations to Peter Rijnbeek and all of our collaborators at the Erasmus University Medical Center for being awarded a contract to establish the Coordination Center for the Data Analysis and Real World Interrogation Network (DARWIN EU). As noted in this EHDEN press release, “DARWIN EU will be able to leverage the extensive work done within the European Health Data and Evidence Network (EHDEN) project funded by the Innovative Medicines Initiative (IMI), and the Observational Health Data Sciences and Informatics (OHDSI) community.”

• Phenotype Phebruary has begun, and we have six interactive forum threads ongoing discussing different phenotypes developments & evaluation. Each daily post will be linked on this page on OHDSI.org: https://www.ohdsi.org/phenotype-phebruary/. You can find each phenotype topic and post from the last week below; please check them out and continue the conversations. Thank you to Azza Shoaibi, Gowtham Rao, Joel Swerdel, Allan Wu and Patrick Ryan for leading these discussions.

Feb 7 • Neutropenia
Feb 8 • Kidney Stones
Feb 9 • Delirium
Feb 10 • Systemic Lupus Erythematosus
Feb 11 • Suicide Attempts
Feb 12 • Parkinson’s Disease and Parkinsonism
Feb 13 • Attention Deficit Hyperactivity Disorder
Feb 14 • Hypertension

• The next CBER Best Seminar will be provided by a veteran collaborator within the OHDSI community. Nicole Pratt (Professor, University of South Australia) will present on “Evaluating Use of Methods for Adverse Event Under Surveillance For Vaccines” at 11 am ET on Wednesday, Feb. 23. This seminar is free and open to the public; you can register here. 

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: Scaling OHDSI open-source community projects, lessons learned by Oncology Work group
Tuesday: CemConnector: A RESTFul application programing interface and client library for the Common Evidence Model (CEM)
Wednesday: Disease Progression Modeling Workbench 360
Thursday: Evaluating Patient Count Vs Hospitalization Risk for Common Clinical Trial Eligibility Criteria: A Case Study for Relapsed/Refractory Lymphoma/Leukemia
Friday: Representation of investigational drugs in the OMOP CDM

Slides

CDM Workgroup | Data Quality Workgroup | Phenotype Phebruary Report | Community Updates

Video Presentations

CDM Workgroup Update (Clair Blacketer)

Data Quality Workgroup Update (Clair Blacketer)

Phenotype Phebruary Report #2 (Patrick Ryan)

The Feb. 8 OHDSI community call featured a trio of presentations:

Community Updates

• Phenotype Phebruary has begun, and we have six interactive forum threads ongoing discussing different phenotypes developments & evaluation. Each daily post will be linked on this page on OHDSI.org: https://www.ohdsi.org/phenotype-phebruary/. You can find each phenotype topic and post from the last week below; please check them out and continue the conversations.

Feb. 1 • Type 2 Diabetes Mellitus
Feb. 2 • Type 1 Diabetes Mellitus
Feb. 3 • Atrial Fibrillation
Feb. 4 • Multiple Myeloma
Feb. 5 • Alzheimer’s Disease
Feb. 6 • Hemorrhagic Events
Feb. 7 • Neutropenia

• The February 2022 edition of The Journey newsletter is now available. If you don’t the newsletter in your email, please subscribe here. What will you find in the latest edition of The Journey?

• Community Updates
• Extracting OHDSI Concepts from Clinical Narratives for COVID Presentation
• OHDSI Goals for 2022
• Recent Publications
• MORE! 

• Longtime OHDSI collaborator Jon Duke will lead a discussion on saying goodbye to manual registries with the creation of interoperable EHR based clinical registries during the next Grand Rounds at Johns Hopkins, led by Paul Nagy. This leverages the forefront of the OHDSI and FHIR communities committed to open standards and open science. This free session takes place Thursday at 12 pm ET, and you can register here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: Diagnostic Accuracy of Code-Based Algorithms to Identify Urinary Tract Infection in U.S. Administrative Claims Databases
Tuesday: Assessing impact on change in incidence on calibration performance across external validation
Wednesday: A journey through VA’s uptake of the OMOP common data model
Thursday: Medication dosage and exposure duration in OMOP CDM: mapping challenges
Friday: There & Back Again: Using Julia to Augment OHDSI R Packages

Slides

Healthcare Systems | Open Source Community | Phenotype Phebruary | Community Updates

Video Presentations

Healthcare Systems Special Interest Group Update (Melanie Philofsky)

Open Source Community Workgroup Introduction Announcement (Adam Black)

Phenotype Phebruary Report #1 (Patrick Ryan)

Patrick Ryan introduced a community-wide activity around developing and evaluating at least 28 phenotypes across the 28 days of February. This presentation includes a discussion on the importance of phenotypes, a closer look at OHDSI tools that can be used in developing and evaluating them, a plan for executing this initiative across the community, and a jump into the Day 1 phenotype: Type 2 Diabetes Mellitus.

Community Updates

• Congratulations to the team of Ross D. Williams, Aniek F. Markus, Cynthia Yang, Talita Duarte-Salles, Scott L. DuVall, Thomas Falconer, Jitendra Jonnagaddala, Chungsoo Kim, Yeunsook Rho, Andrew E. Williams, Amanda Alberga Machado, Min Ho An, María Aragón, Carlos Areia, Edward Burn, Young Hwa Choi, Iannis Drakos, Maria Tereza Fernandes Abrahão, Sergio Fernández-Bertolín, George Hripcsak, Benjamin Skov Kaas-Hansen, Prasanna L. Kandukuri, Jan A. Kors, Kristin Kostka, Siaw-Teng Liaw, Kristine E. Lynch, Gerardo Machnicki, Michael E. Matheny, Daniel Morales, Fredrik Nyberg, Rae Woong Park, Albert Prats-Uribe, Nicole Pratt, Gowtham Rao, Christian G. Reich, Marcela Rivera, Tom Seinen, Azza Shoaibi, Matthew E. Spotnitz, Ewout W. Steyerberg, Marc A. Suchard, Seng Chan You, Lin Zhang, Lili Zhou, Patrick B. Ryan, Daniel Prieto-Alhambra, Jenna M. Reps and Peter R. Rijnbeek on the publication of “Seek COVER: using a disease proxy to rapidly develop and validate a personalized risk calculator for COVID-19 outcomes in an international network” in BMC Medical Research Methodology.

• Congratulations to the team of Seung-Hwa Lee, Jungchan Park, Rae Woong Park, Seo Jeong Shin, Jinseob Kim, Ji Dong Sung, Dae Jung Kim, and Kwangmo Yang on the publication of “Renin-Angiotensin-Aldosterone System Inhibitors and Risk of Cancer: A Population-Based Cohort Study Using a Common Data Model” in Diagnostics. 

• The most recent Asia-Pacific (APAC) Community Call was held last week, and it featured a CDM Workshop led by Clair Blacketer. This was the first of several planned CDM Workshops for 2022, and video of this session is now available. You can also find a written Q&A from the workshop on our APAC Community page.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, has been moved to the new date of June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: Securing OHDSI on AWS for HIPAA and Research Data Management Compliance
Tuesday: Identification of treatment intent from the actual time-to-treatment distribution in prostate cancer patients
Wednesday: The concept of anchoring in observational study design and its influence
Thursday: Summarizing current evidence for the PIONEER study-a-thon: Systematic Literature Review of prostate cancer patients managed with watchful waiting
Friday: LAISDAR – A federated data network to support COVID-19 research in Rwanda

Slides

Presentation | Community Updates

Video

During our Jan. 18 community call, Dr. Hongfang Liu (Mayo Clinic) and Dr. Christopher Chute (Johns Hopkins University) led a session on Extracting OHDSI Concepts from Clinical Narratives for COVID. Following the presentation (approximately 33 minutes), there is a Q&A session. 

Community Updates

• Congratulations to co-authors ChulHyoung Park, Seng Chan You, Hokyun Jeon, Chang Won Jeong, Jin Wook Choi, and Rae Woong Park on the publication of “Development and Validation of the Radiology Common Data Model (R-CDM) for the International Standardization of Medical Imaging Data” which was recently published in the Yonsei Medical Journal.

• Congratulations to co-authors Xiangmin Ji, Guimei Cui, Chengzhen Xu, Jie Hou, Yunfei Zhang, and Yan Ren on the publication of “Combining a Pharmacological Network Model with a Bayesian Signal Detection Algorithm to Improve the Detection of Adverse Drug Events” recently in Frontiers in Pharmacology.

• Congratulations to the team of Seung-Hwa Lee, Jungchan Park, Rae Woong Park, Seo Jeong Shin, Jinseob Kim, Ji Dong Sung, Dae Jung Kim, and Kwangmo Yang on the publication of “Renin-Angiotensin-Aldosterone System Inhibitors and Risk of Cancer: A Population-Based Cohort Study Using a Common Data Model” in Diagnostics.

• Our friends in the EHDEN Project recently highlighted its many successes over the first three years of its five-year project, including harmonizing more than 500 million health records across 27 countries, developing 14 courses (and counting) in the EHDEN Academy, and plenty more. You can read that report here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, has been moved to the new date of June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• Our Janssen collaborators recently announced an opening for two summer interns for its 2022 Observational Health Data Analytics Internship Program. Learn more about this opportunity and apply using that link.

• The #OHDSISocialShowcase continues on Wednesday this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: The VISIT_DETAIL: A Vehicle for Standard Visits
Tuesday: Leveraging APHRODITE to identify bias in statistical phenotyping algorithms
Wednesday: From type 2 diabetes diagnosis to developing complications: a multi-country approach to understanding patients journey
Thursday: Distributed Counterfactual Modeling Approach for Investigating Hospital-Associated Racial Disparities in COVID-19 Mortality
Friday: Design of a framework to detect temporal clinical event trajectories from health data standardized to the OMOP CDM

Slides

Presentation | Community Updates

Video

During our Jan. 18 community call, workgroups came together in GatherTown to discuss Objectives and Key Results (OKRs) to set for 2022. These OKRs will be evaluated quarterly at both the global community level, as well as within the individual workgroups, to measure the success our community is having, and where we need to put greater attention moving forward.

That session was not recorded; it followed our weekly community updates, which are available below.

Community Updates

• Congratulations to co-authors Daniel Morales, Anna Ostropolets, Lana Lai, Anthony Sena, Scott Duvall, Marc Suchard, Katia Verhamme,Peter Rjinbeek, Jose Posada, Waheed Ahmed, Thamer Alshammary, Heba Alghoul, Osaid Alser, Carlos Areia, Clair Blacketer, Ed Burn, Paula Casajust, Seng You, Dalia Dawoud, Asieh Golozar, Menchung Gong, Jitendra Jonnagaddala, Kristine Lynch, Michael Matheny, Evan Minty, Fredrik Nyberg, Albert Uribe, Martina Recalde, Christian Reich, Martijn Scheumie, Karishma Shah, Nigam Shah, Lisa Schilling, David Vizcaya, Lin Zhang, George Hripcsak, Patrick Ryan, Daniel Prieto-Alhambra, Talita Durate-Salles, and Kristin Kostka on the publication of “Characteristics and outcomes of COVID-19 patients with and without asthma from the United States, South Korea, and Europe” which was recently published in the Journal of Asthma.

• Congratulations to Seng Chan You and Harlan Krumholz, who recently published this commentary in Circulation: The Evolution of Evidence-Based Medicine: When the Magic of the Randomized Clinical Trial Meets Real-World Data.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, has been moved to the new date of June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The latest edition of “The Journey” OHDSI newsletter is now available, and it looked back at 12 highlights from the OHDSI community in 2021. If you aren’t receiving this newsletter each month, you can subscribe here. 

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Wednesday: REDHot OMOP: Facilitating Semantic Interoperability in REDCap with FHIR and the OMOP CDM
Thursday: Imputation of Continuous Measurements in Large Healthcare Databases: Comparing the Performance of Imputation Algorithms
Friday: An EUMAEUS investigation: how much can be gained in vaccine safety surveillance by including second dose data?

Patrick Ryan led the first OHDSI Community Call of 2022 with a presentation about what OHDSI can accomplish together this year. While the community listed and voted upon several objectives, Patrick discussed his hope to develop a system to generate evidence that characterizes disease and treatment utilization, estimates the effects of medical interventions, and predicts outcomes of patients within a network of observational health databases.

Other aspects of the discussion included a look at OHDSI workgroups and how they can continue moving forward, 2021 achievements, and more. Both video of the presentation and Patrick’s slides are available below.

Community Updates

• Congratulations to co-authors Nicolas Paris, Antoine Lamer and Adrien Parrot on the study “Transformation and Evaluation of the MIMIC Database in the OMOP Common Data Model: Development and Usability Study” which was published in JMIR Medical Informatics on Dec. 14.

• Congratulations to co-authors Sooin Choi, Soo Jeong Choi, Jin Kuk Kim, Ki Chang Nam, Suehyun Lee, Ju Han Kim and You Kyoung Lee on the study “Preliminary feasibility assessment of CDM-based active surveillance using current status of medical device data in medical records and OMOP-CDM” which was published in Scientific Reports on Dec. 15.

• Congratulations to co-authors Anastasiya Nestsiarovich, Jenna Reps, Michael Matheny, Scott DuVall, Kristine Lynch, Maura Beaton, Xinzhuo Jiang, Matthew Spotnitz, Stephen Pfohl, Nigam Shah, Carmen Olga Torre, Christian Reich, Dong Yun Lee, Sang Joon Son, Seng Chan You, Rae Woong Park, Patrick Ryan & Christophe Lambert on the study “Predictors of diagnostic transition from major depressive disorder to bipolar disorder: a retrospective observational network study” which was published in Translational Psychiatry on Dec. 20.

• Congratulations to co-authors Carlen Reyes, Andrea Pistillo, Sergio Fernández-Bertolín, Martina Recalde, Elena Roel, Diana Puente, Anthony Sena, Clair Blacketer, Lana Lai, Thamir Alshammari, Waheed-UI-Rahman Ahmed, Osaid Alser, Heba Alghoul, Carlos Areia, Dalia Dawoud, Albert Prats-Uribe, Neus Valveny, Gabriel de Maeztu, Luisa Sorlí Redó, Jordi Martinez Roldan, Inmaculada Lopez Montesinos, Lisa M Schilling, Asieh Golozar, Christian Reich, Jose Posada, Nigam Shah, Seng Chan You, Kristine Lynch, Scott DuVall, Michael Matheny, Fredrik Nyberg, Anna Ostropolets, George Hripcsak, Peter Rijnbeek, Marc Suchard, Patrick Ryan, Kristin Kostka, and Talita Duarte-Salles on the study “Characteristics and outcomes of patients with COVID-19 with and without prevalent hypertension: a multinational cohort study” which was published in BMJ Open on Dec. 22.

• Congratulations to co-authors Jenna Reps, Patrick Ryan, and Peter Rijnbeek on the study “Investigating the impact of development and internal validation design when training prognostic models using a retrospective cohort in big US observational healthcare data” which was published in BMJ Open on Dec. 24.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, has been moved to the new date of June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The latest edition of “The Journey” OHDSI newsletter is now available, and it looked back at 12 highlights from the OHDSI community in 2021. If you aren’t receiving this newsletter each month, you can subscribe here.

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: CohortIncidence: A Standardized Framework for Characterizing Incidence Using OMOP Common Data Model and OHDSI tools
Tuesday: Beyond Clinical: Integrating Research Assay Data into the Observational Health Data Sciences and Informatics Common Data Model (OHDSI CDM) through the Surgical Critical Care Initiative (SC2i)
Wednesday: Comparing Data Quality Dashboard results from consecutive ETL iterations: three new utilities
Thursday: Empirical Assessment of Alternative Methods for Identifying Seasonality in Observational Healthcare Data
Friday: ATLAS with a BigQuery backend running Execution Engine – a Software demo

OPENINGS

• Janssen R&D recently posted an “Associate Director, Observational Health Data Analytics” position in its world-class epidemiology department.

• The Bouvé College of Health Sciences and The Roux Institute at Northeastern University seek candidates for two full-time tenure-track Assistant Professor positions in the emerging area of health/healthcare data science. The successful candidate will have primary responsibility for working with the OHDSI Center at the Roux Institute, focusing on education, research and community support of the global Open Source OHDSI initiative. For more information, please reach out to Brianne Olivieri-Mui, Assistant Professor, Department of Health Sciences, at B.mui@northeastern.edu. 

Slides

Main Presentation (Ryan) | Community Updates

Video