The focus of the Aug. 2 OHDS community call was a panel discussion on what it takes to build organizational support for adopting the OMOP CDM and OHDSI tools, as well as building organizational capacity for conducting observational research. Our panelists for this session included: 

• Greg Klebanov (CTO/SVP • Odysseus Data Services, Inc.)
• Ajit Londhe (Senior Manager, Center for Observational Research • AMGEN)
• Keran Moll (Director, HEOR Real World Data & Analytics Research • Regeneron)
• Paul Nagy (Program Director for Graduate Training in Biomedical Informatics and Data Science • Johns Hopkins University)

Video of this call was posted below. Also, Behzad Naderalvojoud presented a new network study coming out of Stanford University: Development and External Validation of ML Models for Identifying Patients at Risk of Postoperative Prolonged Opioid Use (PORPOISE)A Network Study on OMOP Databases.

Videos of both are available at the bottom of this section.

Community Updates

• Congratulations to the team of Karoline Bräuner, Andreas W. Rosen, Adamantia Tsouchnika, Julie S. Walbech, Mikail Gögenur, Viviane A. Lin, Johan Clausen, and Ismail Gögenur on the publication of Developing prediction models for short-term mortality after surgery for colorectal cancer using a Danish national quality assurance database in the International Journal of Colorectal Disease.

• Congratulations to the team of Carina Nina Vorisek, Moritz Lehne, Sophie Anne Ines Klopfenstein, Paula Josephine Mayer, Alexander Bartschke, Thomas Haese, and Sylvia Thun on the publication of Fast Healthcare Interoperability Resources (FHIR) for Interoperability in Health Research: Systematic Review in JMIR Medical Informatics.

• Nominations are now OPEN for the 2022 Titan Awards, which recognize those who have gone above and beyond to foster community engagement, lead research and development efforts, and make significant contributions towards OHDSI’s mission. If there are members or institutions who have made significant contributions that you would like to recognize, please nominate them before the Sept. 2 deadline!

• The latest edition of the OHDSI newsletter is now available, and it includes details about the CDM Update Process presentation, publications from July, community updates, presentations and more. If you don’t subscribe to the newsletter, you can do so here.

• The most recent Asia-Pacific (APAC) community call focused on two of the ongoing APAC network studies: Comparison of mortality, morbidities & healthcare resources utilization between patients with and without a diagnosis of COVID-19, and Real world safety of treatments for multiple sclerosis. Recording from that and all previous meetings, as well as the schedule and link for future meetings, are available on our APAC Community page.

• The OHDSI Social Showcase has returned! Accepted submissions from the European Symposium Collaborator Showcase will be shared on the OHDSI Twitter and LinkedIn feeds. Here are the posters that will be highlighted this week.

Monday – Comparing Data Quality Dashboard results from consecutive ETL iterations: two new visualizations and one utility script (Anne van Winzum)
Tuesday – OHDSI-On-A-Pi: Containerization of OHDSI Software Tools for Use on a Raspberry Pi (Jared Houghtaling)
Wednesday – Integration prospects of the Ukrainian healthcare system with OMOP CDM (Mariia Kolesnyk)
Thursday – Patient treatment trajectory modeling with Markov chains (Markus Haug)
Friday – Assessing treatment effect heterogeneity using the RiskStratifiedEstimation R-package (Alexandros Rekkas)

Job Openings

• Dani Prieto-Alhambra’s team at the University of Oxford is hiring two Research Assistants in Health Data Sciences. In this position, you will support the programming of analytical pipelines for the analysis of routinely collected data mapped to the OMOP Common Data Model. You will prepare analytical packages to run a number of pre-specified analyses, contribute to wider project planning, including ideas for new research projects and manage own research and administrative activities, within guidelines provided by senior colleagues. More information and the application link are available here, and the deadline is August 8, 2022.

• Peter Rijnbeek and his team at Erasmus University is hiring a Secretary for the Darwin EU Coordination Center and Department of Medical Informatics. This position will be responsible for the day-to-day administrative tasks as the personal assistant for Peter Rijnbeek, and will also work as senior secretary for the Department of Medical Informatics, where you will support the staff together with a very experienced colleague. You will play a key role in enabling the research and education delivered by the department. Your work will include the usual responsibilities of a senior secretary such as managing agendas, handing the communication lines, managing changes in personnel, organizing (international meetings and conferences), etc. More information and an application link are available here, and the deadline is Aug. 14, 2022.

• Brianne Olivieri-Mui and her team at The Roux Institute at Northeastern University has one opening for a Postdoctoral Research Fellow beginning on or about September 1, 2022. The fellow will have an opportunity to conduct observational and administrative database research (e.g., analysis of existing datasets) on health outcomes for older adults with HIV or LGBT older adults, under the supervision of the PI. The fellow will devote most of their time to independent research aligned with the PI’s interests and across federated and local research models. More information and an application link are available here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Building Organizational Support | PORPOISE Study | Community Updates

Video Presentation

Building Organizational Support Panel (Paul Nagy, Keran Moll, Greg Klebanov, Ajit Londhe)

PORPOISE Study Introduction and Call for Collaboration (Behzad Naderalvojoud)

The July 26 community call featured a session led by Clair Blacketer, Paul Nagy and Davera Gabriel on what to do when your data does not fit into the OMOP CDM. Our community continues to expand globally, and both individuals and organizations often look for new enhancements to the CDM. There will be a new decision tree and process implemented to try and streamline this procedure and to clarify how data model requests are made and codified, and these were presented and discussed during this meeting. Video of this call is posted below.

Community Updates

• Congratulations to the team of Martijn Schuemie, Faaizah Arshad, Nicole Pratt, Fredrik Nyberg, Thamir Alshammari, George Hripcsak, Patrick Ryan, Daniel Prieto-Alhambra, Lana Lai, Xintong Li, Stephen Fortin, Evan Minty and Marc Suchard on the publication of Vaccine Safety Surveillance Using Routinely Collected Healthcare Data—An Empirical Evaluation of Epidemiological Designs in Frontiers in Pharmacology.

• Congratulations to the team of Jimmy Phuong, Stephanie Hong, Matvey B. Palchuk, Juan Espinoza, Daniella Meeker, David A. Dorr, Galina Lozinski, Charisse Madlock-Brown, and William G. Adams on the publication of Advancing Interoperability of Patient-level Social Determinants of Health Data to Support COVID-19 Research in the AMIA Annual Symposium Proceedings Archive.

• Nominations are now OPEN for the 2022 Titan Awards, which recognize those who have gone above and beyond to foster community engagement, lead research and development efforts, and make significant contributions towards OHDSI’s mission. If there are members or institutions who have made significant contributions that you would like to recognize, please nominate them before the Sept. 2 deadline!

• The next Asia-Pacific (APAC) community call takes place Thursday, July 28 (July 27 in the Western Hemisphere) and will focus on two of the ongoing APAC network studies: Comparison of mortality, morbidities & healthcare resources utilization between patients with and without a diagnosis of COVID-19, and Real world safety of treatments for multiple sclerosis. Links to the meeting and previous recordings are available on our APAC Community homepage.

• Videos from all presentations during the main day of the OHDSI European Symposium are now available.

• The OHDSI Social Showcase has returned! Accepted submissions from the European Symposium Collaborator Showcase will be shared on the OHDSI Twitter and LinkedIn feeds. Here are the posters that will be highlighted this week.

Monday – Mapping of complex constructs in OMOP CDM (Alexander Davydov)
Tuesday – Implementing the OHDSI Community Approach to Phenotype a Complex Medical Condition in European Primary Care Data (Kristin Kostka)
Wednesday – The use of data-driven vs. clinical based propensity score in covid-19 vaccine safety research (Xintong Li)
Thursday – Norwegian registries onto OMOP Common Data Model: mapping challenges and opportunities for pregnancy studies (Elmir Hurley)
Friday – PHAROS, Platform for Harmonizing and Accessing Data in Real-time on Infectious Disease Surveillance Based on OMOP-CDM in Korea (Chungsoo Kim) 

Job Openings

• Peter Rijnbeek and his team at Erasmus University is hiring a Secretary for the Darwin EU Coordination Center and Department of Medical Informatics. This position will be responsible for the day-to-day administrative tasks as the personal assistant for Peter Rijnbeek, and will also work as senior secretary for the Department of Medical Informatics, where you will support the staff together with a very experienced colleague. You will play a key role in enabling the research and education delivered by the department. Your work will include the usual responsibilities of a senior secretary such as managing agendas, handing the communication lines, managing changes in personnel, organizing (international meetings and conferences), etc. More information and an application link are available here, and the deadline is Aug. 14, 2022.

• Dani Prieto-Alhambra’s team at the University of Oxford is hiring two Research Assistants in Health Data Sciences. In this position, you will support the programming of analytical pipelines for the analysis of routinely collected data mapped to the OMOP Common Data Model. You will prepare analytical packages to run a number of pre-specified analyses, contribute to wider project planning, including ideas for new research projects and manage own research and administrative activities, within guidelines provided by senior colleagues. More information and the application link are available here, and the deadline is August 8, 2022.

• Brianne Olivieri-Mui and her team at The Roux Institute at Northeastern University has one opening for a Postdoctoral Research Fellow beginning on or about September 1, 2022. The fellow will have an opportunity to conduct observational and administrative database research (e.g., analysis of existing datasets) on health outcomes for older adults with HIV or LGBT older adults, under the supervision of the PI. The fellow will devote most of their time to independent research aligned with the PI’s interests and across federated and local research models. More information and an application link are available here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Community Updates

Video Presentation

CDM Update Process (Clair Blacketer, Paul Nagy, Davera Gabriel)

The July 19 OHDSI Community Call featured a new set of workgroup updates:

• Early-Stage Researchers (Faaizah Arshad)
• NLP (Hua Xu)
• Phenotype Development & Evaluation (Gowtham Rao)
• HADES (Martijn Schuemie)

Each of the updates are available at the bottom of this section

Community Updates

• Congratulations to the team of Nicholas Tatonetti and Nick Giangreco on the publication of A database of pediatric drug effects to evaluate ontogenic mechanisms from child growth and development in Med. 

• Nominations are now OPEN for the 2022 Titan Awards, which recognize those who have gone above and beyond to foster community engagement, lead research and development efforts, and make significant contributions towards OHDSI’s mission. If there are members or institutions who have made significant contributions that you would like to recognize, please nominate them before the Sept. 2 deadline!

• EHDEN recently announced that 32 applicants from its most recent data partner call have been selected to join the federated data network, which already includes 134 data partners from 26 countries.

• The most recent Asia-Pacific (APAC) community call focused on two of the ongoing APAC network studies: Characterization of Health by OHDSI AP chapter to identify Temporal Effect of the Pandemic (Seng Chan You), and Data quality of OHDSI APAC: CDM Inspection study (Chungsoo Kim). A recording of the presentation is available here: https://youtu.be/h7dCyzjOWoQ. The next APAC call will focus on the other two studies and will be held July 28.

• Videos from all presentations during the main day of the OHDSI European Symposium are now available.

• The latest edition of The Journey Newsletter, which includes updates on the European Symposium, the SNOMED agreement, the 10-minute tutorials, as well as community updates, publications and presentations, is now available here.

• The OHDSI Social Showcase has returned! Accepted submissions from the European Symposium Collaborator Showcase will be shared on the OHDSI Twitter and LinkedIn feeds. Here are the posters that will be highlighted this week.

Monday – Miniaturizing Data Harmonization; Methods to Facilitate Training in the OMOP Data Ecosystem (Emma Gesquiere)
Tuesday – TrajectoryViz: Interactive visualization of treatment trajectories (Maarja Pajusalu)
Wednesday – OMOP project evolvement at Technische Universität Dresden over the past years (Ines Reinecke)
Thursday – Pharmacological treatment pathways of chronic cough in adults in primary care in the Netherlands: A population-based study (Johnmary Arinze, Solomon Ioannou)
Friday – De-identification of Clinical Notes for Patients with Infectious Disease and Topic Modeling using Latent Dirichlet Allocation (Junhyuk Chang)

Job Openings

• Dani Prieto-Alhambra’s team at the University of Oxford is hiring two Research Assistants in Health Data Sciences. In this position, you will support the programming of analytical pipelines for the analysis of routinely collected data mapped to the OMOP Common Data Model. You will prepare analytical packages to run a number of pre-specified analyses, contribute to wider project planning, including ideas for new research projects and manage own research and administrative activities, within guidelines provided by senior colleagues. More information and the application link are available here, and the deadline is August 8, 2022.

• Brianne Olivieri-Mui and her team at The Roux Institute at Northeastern University has one opening for a Postdoctoral Research Fellow beginning on or about September 1, 2022. The fellow will have an opportunity to conduct observational and administrative database research (e.g., analysis of existing datasets) on health outcomes for older adults with HIV or LGBT older adults, under the supervision of the PI. The fellow will devote most of their time to independent research aligned with the PI’s interests and across federated and local research models. More information and an application link are available here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Early-Stage Researchers | NLP | Phenotype Development & Evaluation | HADES | Community Updates

Video Presentation

Early-Stage Researchers (Faaizah Arshad)

NLP (Hua Xu)

Phenotype Development & Evaluation (Gowtham Rao)

HADES (Martijn Schuemie)

The July 12 OHDSI Community Call focused on new adopters and/or new community members. We were excited to hear from 22 people from around the world who are beginning their OHDSI journey. 

You can hear their backgrounds, research interests and ways they hope to enhance the community in the video presentation below.

Community Updates

• Congratulations to the team of Ines Reinecke, Mirko Gruhl, Martin Pinnau, Fatma Betül Altun, Michael Folz, Michéle Zoch, Franziska Bathelt, and Martin Sedlmayr on the recent publication of An OHDSI ATLAS Extension to Support Feasibility Requests in a Research Network in Volume 295 of Studies in Health Technology and Informatics.

• Congratulations to the team of Anthony Molinaro and Frank DeFalco on the publication of Empirical assessment of alternative methods for identifying seasonality in observational healthcare data in BMC Medical Research Methodology.

• Congratulations to the team of Gayathri Delanerolle, Robert Williams, Ana Stipancic, Rachel Byford, Anna Forbes, Sneha Anand, Declan Bradley, Ruby Tsang, Siobhán Murphy, Ashley Akbari, Stuart Bedston, Ronan Lyons, Rhiannon Owen, Jillian Beggs, Antony Chuter, Domnique Balharry, Mark Joy, Aziz Sheikh, F.D. Richard Hobbs, and Simon de Lusignan on the publication of Methodological issues for using a common data model (CDM) of COVID-19 vaccine uptake and important adverse events of interest (AEIs): the Data and Connectivity COVID-19 Vaccines Pharmacovigilance (DaC-VaP) United Kingdom feasibility study in JMIR Formative Research.

• Congratulations to the team of Yae Won Tak, Seng Chan You, Jeong Hyun Han, Soon-Seok Kim, Gi-Tae Kim and Yura Lee on the publication of Perceived Risk of Re-Identification in OMOP-CDM Database: A Cross-Sectional Survey in the Journal of Korean Medical Science.

• Congratulations to the team of Erica Voss, Saberi Rana Ali, Arun Singh, Peter Rijnbeek, Martijn Schuemie, and Daniel Fife on the publication of Hip Fracture Risk After Treatment with Tramadol or Codeine: An Observational Study in Drug Safety.

• Congratulations to the team of Emily Pfaff, Andrew Girvin, Tellen Bennett, Abhishek Bhatia, Ian Brooks, Rachel Deer, Jonathan Dekermanjian, Sarah Elizabeth Jolley, Michael Kahn, Kristin Kostka, Julie McMurry, Richard Moffitt, Anita Walden, Christopher Chute, Melissa A Haendel, and the N3C Consortium on the recent publication of Identifying who has long COVID in the USA: a machine learning approach using N3C data in The Lancet Digital Health.

• Nominations are now OPEN for the 2022 Titan Awards, which recognize those who have gone above and beyond to foster community engagement, lead research and development efforts, and make significant contributions towards OHDSI’s mission. If there are members or institutions who have made significant contributions that you would like to recognize, please nominate them before the Sept. 2 deadline!

• Videos from all presentations during the main day of the OHDSI European Symposium are now available.

• The latest edition of The Journey Newsletter, which includes updates on the European Symposium, the SNOMED agreement, the 10-minute tutorials, as well as community updates, publications and presentations, is now available here.

• The OHDSI Social Showcase has returned! Accepted submissions from the European Symposium Collaborator Showcase will be shared on the OHDSI Twitter and LinkedIn feeds. Here are the posters that will be highlighted this week.

Monday – Mapping concepts from the Netherlands Cancer Registry to the OMOP-CDM – experiences and challenges (Chiara Attanasio)
Tuesday – The journey from central operational data-lake to Medica Centers CDM network (Guy Livne)
Wednesday – Informativeness of clinical lymph node metastasis staging for patients undergoing curative intended surgery for colorectal cancer: A national multi-register study (Andreas Weinberger Rosen)
Thursday – Concept extraction from Dutch clinical text (Tom Seinen)
Friday – OHDSI Italia: the Italian national node of OHDSI Europe (Lucia Sacchi)

Job Openings

• Dani Prieto-Alhambra’s team at the University of Oxford is hiring two Research Assistants in Health Data Sciences. In this position, you will support the programming of analytical pipelines for the analysis of routinely collected data mapped to the OMOP Common Data Model. You will prepare analytical packages to run a number of pre-specified analyses, contribute to wider project planning, including ideas for new research projects and manage own research and administrative activities, within guidelines provided by senior colleagues. More information and the application link are available here, and the deadline is August 8, 2022.

• Brianne Olivieri-Mui and her team at The Roux Institute at Northeastern University has one opening for a Postdoctoral Research Fellow beginning on or about September 1, 2022. The fellow will have an opportunity to conduct observational and administrative database research (e.g., analysis of existing datasets) on health outcomes for older adults with HIV or LGBT older adults, under the supervision of the PI. The fellow will devote most of their time to independent research aligned with the PI’s interests and across federated and local research models. More information and an application link are available here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Community Updates

Video Presentation

New Community Member Introductions

The June 28 OHDSI Community Call, featured a full review of the 2022 OHDSI European Symposium! 

Nigel Hughes, Director, Observational Health Data Analytics at Janssen Research & Development, provided a review of the 2022 OHDSI European Symposium, held June 24-26 in Rotterdam. This presentation highlights the panels, talks and collaborator showcase from Day 1, and it also includes details on the Day 2 and Day 3 workshops.

Keep following OHDSI.org for more information on the European Symposium, including recordings from all events when they are available.

There will be no community call on July 5.

Community Updates

• Thank you to everybody who submitted brief reports to join our #OHDSI2022 Collaborator Showcase. We had a record amount (more than 130!) of submissions for poster presentations, software demos and oral presentations for the 2022 OHDSI Symposium, which will be held Oct. 14-16 in Bethesda, Md. The scientific committee meets this week to begin the process of reviewing all submissions, and selected presenters will be notified by August 1, 2022.

• Our July 12 Community Call will be focused on new adopters of the OMOP CDM or new members of the OHDSI community. We are welcoming people to introduce themselves, share why they have joined the community and what impact they hope to make, and also ask a question to the broader community. If you would like to take part in this event, please fill out this form to help us plan the session.

• The OHDSI Social Showcase has returned! Accepted submissions from the European Symposium Collaborator Showcase will be shared on the OHDSI Twitter and LinkedIn feeds. Here are the posters that will be highlighted this week.

Monday – Why predicting risk can’t identify ‘risk factors’: empirical assessment of model stability in machine learning across observational health databases (Aniek Markus)
Tuesday – OMOP Genomic mapping capacities in conversion of comprehensive genomic profiling results (Maria Rogozhkina)
Wednesday – Perseus Design and run your own ETL to CDM (Anton Ivanov)
Thursday – Using geospatial approaches and machine learning for asthma and COPD outcomes: a systematic review (Daniel Jeannetot)
Friday – A pilot study to evaluate the feasibility of using Observational Health Data Sciences and Informatics analytics tools for supporting the validation of safety signals (Ceyda Pekmez)

• On behalf of the Health Systems Special Interest Group, lead Melanie Philofsky shared this recent forum post requesting assistance in a creating central repository of different OMOP sites, their underlying EHR system, and attributes. If you can add to this repository and enhance community knowledge, please fill out this form.

• As mentioned during the video presentation below, the launch of the EHDEN Portal was announced during the European Symposium. The Portal includes a Data Partner Catalogue and Feasibility Dashboards that support data discoverability (findable under Findable, Accessible, Interoperable and Reusable (FAIR) principles). The Portal represents the start of an open platform to facilitate identifying data that is likely to be used for a research topic, through the study workflow to analytical results. It gives researchers more granular insights into EHDEN’s 140-strong Data Partner network with currently more than 500 million anonymous patient records being mapped to the OMOP common data model local to the data.

Job Openings

• Odysseus Data Services posted two new openings recently. There are currently openings for an epidemiologist and a data scientist. Please check out the links for more information and/or to apply for these jobs.

• Professor Peter Rijnbeek announced an opening for an epidemiologist to work with his team at Erasmus MC. This position will be responsible for all aspects of observational research including protocol writing, input in the statistical analysis plan, study execution, interpretation of results and report/manuscript writing. The application deadline is July 8, 2022.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

European Symposium Review | Community Updates

Video Presentation

European Symposium Review (Nigel Hughes)

The June 21 OHDSI Community Call featured four 10-minute tutorials on open-source tools developed within our community for use in global research initiatives: 

PheValuator
Presenter: Joel Swerdel • Associate Director, Johnson & Johnson

PheKnowLater
Presenter: Tiffany Callahan • Postdoctoral Research Fellow, Columbia University

Patient-Level Prediction
Presenter: Jenna Reps • Associate Director, Johnson & Johnson

CAPR (Cohort definition Application Programming in R)
Presenter: Martin Lavallee • Data Scientist, Odysseus Data Services

Community Updates

• Showcase submission week has arrived! All submissions for poster presentations, software demos and/or lightning talks are due no later than 8pm (EST) on Friday, June 24. For more information, please visit our Collaborator Showcase homepage.

Congratulations to the team of Jiayi Tong, Chongliang Luo, Md Nazmul Islam, Natalie E. Sheils, John Buresh, Mackenzie Edmondson, Peter A. Merkel, Ebbing Lautenbach, Rui Duan and Yong Chen on the publication of Distributed learning for heterogeneous clinical data with application to integrating COVID-19 data across 230 sites in Digital Medicine.

• Congratulations to the team of Emmanuel Uchenna Agu, Arman Mosenia, Jacob A Lifton, Lawrence Chan, Katherine G Ligtenberg, Drew Saylor, Reza Vagefi, Seanna R Grob, Robert Kersten, Melena Ahmad, and Bryan Winnon on the publication of The Impact of COVID-19 on Periocular Non-Melanoma Skin Cancer in the Veteran Population in Investigative Ophthalmology & Visual Science.

• Congratulations to the team of Yongseok Mun, ChulHyoung Park, Da Yun Lee, Tong Min Kim, Ki Won Jin, Seok Kim, Yoo-Ri Chung, Kihwang Lee, Ji Hun Song, Young-Jung Roh, Donghyun Jee, Jin-Woo Kwon, Se Joon Woo, Kyu Hyung Park, Rae Woong Park, Sooyoung Yoo, Dong-Jin Chang & Sang Jun Park on the publication of Real-world treatment intensities and pathways of macular edema following retinal vein occlusion in Korea from Common Data Model in ophthalmology in Scientific Reports.

• Congratulations to the team of Sooyoung Yoo, Eunsil Yoon, Dachung Boo, Borham Kim, Seok Kim, Jin Chul Paeng, Ie Ryung Yoo, In Young Choi, Kwangsoo Kim, Hyun Gee Ryoo, Sun Jung Lee, Eunhye Song, Young-Hwan Joo, Junmo Kim, and Ho-Young Lee on the publication of Transforming Thyroid Cancer Diagnosis and Staging Information from Unstructured Reports to the Observational Medical Outcome Partnership Common Data Model in Applied Clinical Informatics.

• Congratulations to the team of Cynthia Yang, Ross Williams, Joel Swerdel, João Rafael Almeida, Emily S. Brouwer, Edward Burn, Loreto Carmona, Katerina Chatzidionysiou, Talita Duarte-Salles, Walid Fakhouri, Antje Hottgenroth, Meghna Jani, Raivo Kolde, Jan A. Kors, Lembe Kullamaa, Jennifer Lane, Karine Marinier, Alexander Michel, Henry Morgan Stewart, Albert Prats-Uribe, Sulev Reisberg, Anthony Sena, Carmen Torre, Katia Verhamme, David Vizcaya, James Weaver, Patrick Ryan, Daniel Prieto-Alhambra, and Peter Rijnbeek on the publication of Development and external validation of prediction models for adverse health outcomes in rheumatoid arthritis: A multinational real-world cohort analysis in Seminars in Arthritis and Rheumatism.

• Congratulations to the team of Anna Ostropolets, Patrick Ryan, Martijn Schuemie, and George Hripcsak on the publication of Characterizing Anchoring Bias in Vaccine Comparator Selection Due to Health Care Utilization With COVID-19 and Influenza: Observational Cohort Study in JMIR Public Health and Surveillance.

• Congratulations to OHDSI veteran and Australia Chapter lead Nicole Pratt, who was recent named one of eight new ISPE Fellows for 2022. Nicole, whose interest in the effectiveness and safety of medicine use has led her to collaborate on network initiatives like LEGEND and EUMAEUS, was featured in the latest edition of the OHDSI Collaborator Spotlight.

• On behalf of the Health Systems Special Interest Group, lead Melanie Philofsky shared this recent forum post requesting assistance in a creating central repository of different OMOP sites, their underlying EHR system, and attributes. If you can add to this repository and enhance community knowledge, please fill out this form.

• Our July 12 community call will focus on new adopters of OMOP and/or new members of the community. We are looking for people to introduce themselves, and offering an opportunity to ask questions to the community. If you would like to be part of this call, please let us know!

Job Openings

• Odysseus Data Services posted two new openings recently. There are currently openings for an epidemiologist and a data scientist. Please check out the links for more information and/or to apply for these jobs.

• Professor Peter Rijnbeek announced an opening for an epidemiologist to work with his team at Erasmus MC. This position will be responsible for all aspects of observational research including protocol writing, input in the statistical analysis plan, study execution, interpretation of results and report/manuscript writing. The application deadline is July 8, 2022.

• Professor Dani Prieto-Alhambra announced an opening for a postdoctoral data scientist to work with his team at the University of Oxford. This position will develop analysis plans, protocols, ethical (and similar panel) submissions, governance and regulatory submissions as required for ongoing and future studies. It will generate and analyze OMOP-mapped real world health data assets, adapt existing and develop new research methodologies and materials. The application deadline is June 27, 2022.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

PheValuator | PheKnowLator | CAPR | Community Updates

Video Presentations

PheValuator (Joel Swerdel)

PheKnowLator (Tiffany Callahan)

Patient-Level Prediction (Jenna Reps)

Cohort definition Application Programming in R (Martin Lavallee)

Our OHDSI community produced nearly 40 peer-reviewed and published studies over the first five months of 2022, and five of the study leads were presented during our June 14 community call.

Analysis of Dual Combination Therapies Used in Treatment of Hypertension in a Multinational Cohort
Presenter: Yuan Lu • Assistant Professor, Yale University

Factors Influencing Background Incidence Rate Calculation: Systematic Empirical Evaluation Across an International Network of Observational Databases
Presenter: Anna Ostropolets • PhD Student, Columbia University

Logistic regression models for patient-level prediction based on massive observational data: Do we need all data?
Presenter: Henrik John • PhD Student, Erasmus University

Learning patient-level prediction models across multiple healthcare databases: evaluation of ensembles for increasing model transportability
Presenter: Jenna Reps • Associate Director, Johnson & Johnson

Prior-Preconditioned Conjugate Gradient Method for Accelerated Gibbs Sampling in “Large n, Large p” Bayesian Sparse Regression
Presenter: Aki Nishimura • Assistant Professor, Johns Hopkins University

Community Updates

• Congrats to the team of Rohan Khera, Martijn Schuemie , Yuan Lu , Anna Ostropolets, RuiJun Chen, George Hripcsak, Patrick Ryan, Harlan Krumholz, and Marc Suchard on the recent publication of Large-scale evidence generation and evaluation across a network of databases for type 2 diabetes mellitus (LEGEND-T2DM): a protocol for a series of multinational, real-world comparative cardiovascular effectiveness and safety studies in BMJ Open.

• Congratulations to the team of Paul Heidera, Ronak Pipaliyab, and Stéphane Meystre on the publication of A Natural Language Processing Tool Offering Data Extraction for COVID-19 Related Information (DECOVRI) in Volume 290 of Studies in Health Technology and Informatics.

• Congratulations to the team of Lamy Jean-Baptistea, Abdelmalek Mouazera, Karima Sedkia, and Rosy Tsopra on the publication of Translating the Observational Medical Outcomes Partnership – Common Data Model (OMOP-CDM) Electronic Health Records to an OWL Ontology in Volume 290 of Studies in Health Technology and Informatics.

• Congratulations to the team of Mélanie Buy, William Digan, Xiaoyi Chen, Julien Husson, Mickael Ménager, Frédéric Rieux Laucat, Nicolas Garcelon, and ATRACTion members on the publication of A Multi-Omics Common Data Model for Primary Immunodeficiencies in Volume 290 of Studies in Health Technology and Informatics.

• The latest edition of the OHDSI Collaborator Spotlight focuses on community veteran and Australia chapter lead Nicole Pratt, whose interest in the effectiveness and safety of medicine use has led her to collaborate on network initiatives like LEGEND and EUMAEUS. She has also played an important role in the continued growth of the APAC community. She shares about her journey to OHDSI, her roles in the community and more in this spotlight.

• The OHDSI community and SNOMED International have formalized their long-time relationship with a five-year collaborative agreement that will benefit both of their user communities. The SNOMED collaboration provides OHDSI and its user community with comprehensive ontologies on specific healthcare domains and content such as devices, social determinants of health, disease severity scores and modifiers of cancers, as well as better concept definitions and resolutions of composite concepts in large-scale observational research. In return, OHDSI and its user community can provide SNOMED International with information and feedback on clinical validation, frequency of use data, and validation of SNOMED CT content modeling. Learn more in the full media release.

• The CBER Best Seminar Series is being rescheduled moving forward. Please be on the lookout for more information on when it will resume and who will be added to the schedule.

• We are less than two weeks away from the submission deadline for the 2022 OHDSI Global Symposium. All submissions for poster presentations, software demos and/or lightning talks are due no later than 8pm (EST) on Friday, June 24. For more information, please visit our Collaborator Showcase homepage. 

Job Openings

• Professor Peter Rijnbeek announced an opening for an epidemiologist to work with his team at Erasmus MC. This position will be responsible for all aspects of observational research including protocol writing, input in the statistical analysis plan, study execution, interpretation of results and report/manuscript writing. The application deadline is July 8, 2022.

• Professor Dani Prieto-Alhambra announced an opening for a postdoctoral data scientist to work with his team at the University of Oxford. This position will develop analysis plans, protocols, ethical (and similar panel) submissions, governance and regulatory submissions as required for ongoing and future studies. It will generate and analyze OMOP-mapped real world health data assets, adapt existing and develop new research methodologies and materials. The application deadline is June 27, 2022.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Lu | Ostropolets | John | Reps | Nishimura | Community Updates

Video Presentations

Analysis of Dual Combination Therapies Used in Treatment of Hypertension in a Multinational Cohort (Lu)

Factors Influencing Background Incidence Rate Calculation: Systematic Empirical Evaluation Across an International Network of Observational Databases (Ostropolets)

Logistic regression models for patient-level prediction based on massive observational data: Do we need all data? (John)

Learning patient-level prediction models across multiple healthcare databases: evaluation of ensembles for increasing model transportability (Reps)

Prior-Preconditioned Conjugate Gradient Method for Accelerated Gibbs Sampling in “Large n, Large p” Bayesian Sparse Regression (Nishimura)

Patrick Ryan and Craig Sachson provided an overview of the OHDSI community, a tour of the OHDSI website and Teams environment, and a preview of the OHDSI Symposium collaborator showcase. Paul Nagy shared his journey to the community, and there was a brief Q&A session.

For all newcomers to the community, we will have a community call on July 12 focused on meeting new adopters of OMOP and answering any questions you might have.

Community Updates

• Congratulations to the team of Azza Shoaibi, Gowtham Rao, Erica Voss, Anna Ostropolets, Miguel Angel Mayer, Juan Manuel Ramírez-Anguita, Filip Maljković, Biljana Carević, Scott Horban, Daniel R. Morales, Talita Duarte-Salles, Clement Fraboulet, Tanguy Le Carrour, Spiros Denaxas, Vaclav Papez, Luis H. John, Peter R. Rijneek, Evan Minty, Thamir M. Alshammari, Rupa Makadia, Clair Blacketer, Frank DeFalco, Anthony Sena, Marc Suchard, Daniel Prieto-Alhambra and Patrick Ryan on the publication of Phenotype Algorithms for the Identification and Characterization of Vaccine-Induced Thrombotic Thromlbocytopenia in Real World Data: A Multinational Network Cohort Study in Drug Safety.

• The OHDSI community and SNOMED International have formalized their long-time relationship with a five-year collaborative agreement that will benefit both of their user communities. The SNOMED collaboration provides OHDSI and its user community with comprehensive ontologies on specific healthcare domains and content such as devices, social determinants of health, disease severity scores and modifiers of cancers, as well as better concept definitions and resolutions of composite concepts in large-scale observational research. In return, OHDSI and its user community can provide SNOMED International with information and feedback on clinical validation, frequency of use data, and validation of SNOMED CT content modeling. Learn more in the full media release.

• The June edition of the OHDSI newsletter is now available. This edition includes the DARWIN EU presentation and corresponding slides, a collaborator spotlight on Asieh Golozar, the latest on open studies in the global community, the monthly update podcast and other community updates, all publications and presentation from May, and plenty more. If you aren’t already a subscriber, you can do so here.

• The CBER Best Seminar Series is being rescheduled moving forward. Please be on the lookout for more information on when it will resume and who will be added to the schedule.

• We are less one month away from the submission deadline for the 2022 OHDSI Global Symposium. All submissions for poster presentations, software demos and/or lightning talks are due no later than 8pm (EST) on Friday, June 24. For more information, please visit our Collaborator Showcase homepage.

• The Roux Institute will host a one-day Symposium on Risks and Opportunities of AI in Clinical Drug Development on June 6. The event will be held in Portland, Maine, though you can attend this event virtually as well. The event, sponsored by Pfizer Inc., Northeastern University, the American Statistical Association (ASA), the Statistics Department and Data Science Institute at Columbia University, and OHDSI, is designed to serve as a platform for distinguished statisticians, data scientists, regulators, and other professionals to address the challenges and opportunities of AI in pharmaceutical medicine; to foster collaboration among industry, academia, regulatory agencies, and professional associations; and to propose recommendations with policy implications for proper implementation of AI in promoting public health.

Job Openings

• Professor Dani Prieto-Alhambra announced an opening for a Postdoctoral Data Scientist to work with his team at the University of Oxford. This position will develop analysis plans, protocols, ethical (and similar panel) submissions, governance and regulatory submissions as required for ongoing and future studies. It will generate and analyze OMOP-mapped real world health data assets, adapt existing and develop new research methodologies and materials. It will carry out collaborative research projects with colleagues in partner institutions and report research findings in the form of conference abstracts at national and international conferences. You can learn more and apply here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Welcome To OHDSI | Community Updates

Video Presentation

Leads from the OHDSI workgroups joined the May 31 Community Call to go around and present what is happening within their respective teams in relation to 2022 objectives and key results. This was an opportunity for the community to learn about all the current work happening around our community and to see how you can collaborate with our workgroups to achieve these goals.

Community Updates

• Congratulations to the team of Jenna Reps, Ross Williams, Martijn Schuemie, Patrick Ryan & Peter Rijnbeek on the publication of Learning patient-level prediction models across multiple healthcare databases: evaluation of ensembles for increasing model transportability in BMC Medical Informatics and Decision Making. 

• Congratulations to the team of Elisa Henke, Ines Reinecke, Michele Zoch, Martin Sedlmayr, and Franziska Bathelt on the publication of Towards the Improvement of Clinical Guidelines Based on Real World Data in Volume 294 of Studies in Health Technology and Informatics.

• Congratulations to the team of Jose Manuel Saborit-Torres, Silvia Nadal-Almela, Joaquim Angel Montell-Serrano, Elena Oliver-Garcia, Hector Carceller, Jon Ander Gómez-Ádrian, Marisa Caparrós-Redondo, Francisco García-García, Julio Domenech-Fernández and Maria De La Iglesia-Vayá on the publication of Beyond the Brain: MIDS Extends BIDS to Multiple Modalities and Anatomical Regions in Volume 294 of Studies in Health Technology and Informatics.

• Congratulations to the team of Ines Reinecke, Michael Kallfelz, Martin Sedlmayr, Joscha Siebel and Franziska Bathelt on the publication of Evaluation and Challenges of Medical Procedure Data Harmonization to SNOMED-CT for Observational Research in Volume 294 of Studies in Health Technology and Informatics.

• Congratulations to the team of Daniel Puttmann, Nicolette De Keizer, Ronald Cornet, Eric Van Der Zwan, Ferishta Bakhshi-Raiez on the publication of FAIRifying a Quality Registry Using OMOP CDM: Challenges and Solutions in Volume 294 of Studies in Health Technology and Informatics.

• Congratulations to the team of Emmanuelle Theron, Jean-François Gorse, and Xavier Gansel on the publication of Usability of OMOP Common Data Model for Detailed Lab Microbiology Results in Volume 294 of Studies in Health Technology and Informatics.

• Congratulations to the team of Franziska Bathelt, Ines Reinecke, Yuan Peng, Elisa Henke, Jens Weidner, Martin Bartos, Robert Gött, Dagmar Waltemath, Katrin Engelmann, Peter Schwarz, and Martin Sedlmayr on the publication of Opportunities of Digital Infrastructures for Disease Management—Exemplified on COVID-19-Related Change in Diagnosis Counts for Diabetes-Related Eye Diseases in Nutrients.

• We are less one month away from the submission deadline for the 2022 OHDSI Global Symposium. All submissions for poster presentations, software demos and/or lightning talks are due no later than 8pm (EST) on Friday, June 24. For more information, please visit our Collaborator Showcase homepage.

• The Roux Institute will host a one-day Symposium on Risks and Opportunities of AI in Clinical Drug Development on June 6. The event will be held in Portland, Maine, though you can attend this event virtually as well. The event, sponsored by Pfizer Inc., Northeastern University, the American Statistical Association (ASA), the Statistics Department and Data Science Institute at Columbia University, and OHDSI, is designed to serve as a platform for distinguished statisticians, data scientists, regulators, and other professionals to address the challenges and opportunities of AI in pharmaceutical medicine; to foster collaboration among industry, academia, regulatory agencies, and professional associations; and to propose recommendations with policy implications for proper implementation of AI in promoting public health.

Job Openings

• Professor Dani Prieto-Alhambra announced an opening for a Postdoctoral Data Scientist to work with his team at the University of Oxford. This position will develop analysis plans, protocols, ethical (and similar panel) submissions, governance and regulatory submissions as required for ongoing and future studies. It will generate and analyze OMOP-mapped real world health data assets, adapt existing and develop new research methodologies and materials. It will carry out collaborative research projects with colleagues in partner institutions and report research findings in the form of conference abstracts at national and international conferences. You can learn more and apply here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration
Oct. 15-16 – Workgroup Activities: Information | Registration

Slides

Community Updates & OKRs

Video Presentations

Around The Workgroups

The May 24 OHDSI Community Call shared six open studies that are ongoing in our global network:

IBD characterization
Presenter: Chen Yanover

Characterization of Health by OHDSI Asia-Pacific chapter to identify Temporal Effect of the Pandemic (CHAPTER) Study
Presenter: Seng Chan You

Applying the Decentralized Generalized Linear Mixed Effects Model (dGEM) for Hospital Profiling of COVID-19 Mortality Data across OHDSI Network
Presenter: Jessie Tong

Real world safety of treatments for multiple sclerosis
Presenter: Nicole Pratt

Comparison of mortality, morbidities & healthcare resources utilization between patients with and without a diagnosis of COVID-19
Presenter: Ivan Lam

Quality assessment of CDM databases across the OHDSI-AP network
Presenter: Chungsoo Kim

Community Updates

• Congratulations to the team of Emily Pfaff, Andrew Girvin, Tellen Bennett, Abhishek Bhatia, Ian Brooks, Rachel Deer, Jonathan Dekermanjian, Sarah Elizabeth Jolley, Michael Kahn, Kristin Kostka, Julie McMurry, Richard Moffitt, Anita Walden, Christopher Chute, Melissa Haendel, and the N3C Consortium on the publication of Identifying who has long COVID in the USA: a machine learning approach using N3C data in The Lancet Digital Health.

• Congratulations to the team of Jin Ge, W. Ray Kim, Jennifer Lai, and Allison Kwong on the publication of “Beyond MELD” – Emerging strategies and technologies for improving mortality prediction, organ allocation and outcomes in liver transplantation in the Journal of Hepatology.

• Congratulations to the team of Justin T. Reese, Ben Coleman, Lauren Chan, Hannah Blau, Tiffany J. Callahan, Luca Cappelletti, Tommaso Fontana, Katie R. Bradwell, Nomi L. Harris, Elena Casiraghi, Giorgio Valentini, Guy Karlebach, Rachel Deer, Julie A. McMurry, Melissa A. Haendel, Christopher G. Chute, Emily Pfaff, Richard Moffitt, Heidi Spratt, Jasvinder A. Singh, Christopher J. Mungall, Andrew E. Williams & Peter N. Robinson for the publication of NSAID use and clinical outcomes in COVID-19 patients: a 38-center retrospective cohort study in Virology Journey.

• We are approximately one month away from the submission deadline for the 2022 OHDSI Global Symposium. All submissions for poster presentations, software demos and/or lightning talks are due no later than 8pm (EST) on Friday, June 24. For more information, please visit our Collaborator Showcase homepage.

• The CDM Workshop that was supposed to be held last Thursday, May 19, has been moved to this Thursday, May 26 (1 pm ET). It will focus on ETL Vocabulary Mapping. If you are interested in taking part, please fill out this form.

• The Roux Institute will host a one-day Symposium on Risks and Opportunities of AI in Clinical Drug Development on June 6. The event will be held in Portland, Maine, though you can attend this event virtually as well. The event, sponsored by Pfizer Inc., Northeastern University, the American Statistical Association (ASA), the Statistics Department and Data Science Institute at Columbia University, and OHDSI, is designed to serve as a platform for distinguished statisticians, data scientists, regulators, and other professionals to address the challenges and opportunities of AI in pharmaceutical medicine; to foster collaboration among industry, academia, regulatory agencies, and professional associations; and to propose recommendations with policy implications for proper implementation of AI in promoting public health.

• EHDEN is now hosting its sixth open call for data partners looking to map their patient data to the OMOP CDM. Through its first five open calls, EHDEN has created a federated data network of 140 partners across 26 countries, and it has also trained and certified 47 SMEs to assist with mapping this data. Data Partners can benefit from up to a maximum of €100 000 funding. The deadline to apply is June 14, 2022.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase

Oct. 15 – Tutorial: Information | Registration

Oct. 15-16 – Workgroup Activities: Information | Registration

Slides 

Yanover | You | Tong | Pratt | Lam | Kim | Community Updates

Video Presentations

IBD characterization (Yanover)

Characterization of Health by OHDSI Asia-Pacific chapter to identify Temporal Effect of the Pandemic (CHAPTER) Study (You)

https://https://youtu.be/swSC-IQdXms

Applying the Decentralized Generalized Linear Mixed Effects Model (dGEM) for Hospital Profiling of COVID-19 Mortality Data across OHDSI Network (Tong)

Real world safety of treatments for multiple sclerosis (Pratt)

Comparison of mortality, morbidities & healthcare resources utilization between patients with and without a diagnosis of COVID-19 (Lam)

Applying the DecentraQuality assessment of CDM databases across the OHDSI-AP network (Kim)

The May 17 OHDSI Community Call brought back a popular format, the OHDSI Debates. We hosted two debates and had the community vote on the winner!

Debate 1: Phenotype Development: One-size-fits-all vs. Tailored-per-databases

Debaters: Azza Shoaibi (Associate Director, Janssen Research & Development) and Asieh Golozar (VP, Global Head of Data Science, Odysseus Data Services, Inc.)

Debate 2: Study Diagnostics: Nice-to-have vs. Essential requirements

Debaters: Dani Prieto-Alhambra (Professor, Univ. of Oxford and Erasmus Univ.) and Martijn Schuemie (Research Fellow, Epidemiology Analytics, Janssen Research & Development

Community Updates

• Congratulations to the team of Justin Reese, Ben Coleman, Lauren Chan, Hannah Blau, Tiffany J. Callahan, Luca Cappelletti, Tommaso Fontana, Katie R. Bradwell, Nomi L. Harris, Elena Casiraghi, Giorgio Valentini, Guy Karlebach, Rachel Deer, Julie A. McMurry, Melissa A. Haendel, Christopher G. Chute, Emily Pfaff, Richard Moffitt, Heidi Spratt, Jasvinder A. Singh, Christopher J. Mungall, Andrew E. Williams & Peter N. Robinson on the publication of NSAID use and clinical outcomes in COVID-19 patients: a 38-center retrospective cohort study in Virology Journal.

• Congratulations to the team of Edward Burn, Talita Duarte-Salles, Sergio Fernandez-Bertolin, Carlen Reyes, Kristin Kostka, Antonella Delmestri, Peter Rijnbeek, Katia Verhamme, and Daniel Prieto-Alhambra on the publication of Venous or arterial thrombosis and deaths among COVID-19 cases: a European network cohort study in The Lancet Infectious Diseases.

• The next CDM Workshop will be held inside MS Teams this Thursday, May 19 (1 pm ET), and it will focus on ETL Vocabulary Mapping. If you are interested in taking part, please fill out this form.

• The Roux Institute will host a one-day Symposium on Risks and Opportunities of AI in Clinical Drug Development on June 6. The event will be held in Portland, Maine, though you can attend this event virtually as well. The event, sponsored by Pfizer Inc., Northeastern University, the American Statistical Association (ASA), the Statistics Department and Data Science Institute at Columbia University, and OHDSI, is designed to serve as a platform for distinguished statisticians, data scientists, regulators, and other professionals to address the challenges and opportunities of AI in pharmaceutical medicine; to foster collaboration among industry, academia, regulatory agencies, and professional associations; and to propose recommendations with policy implications for proper implementation of AI in promoting public health.

• EHDEN is now hosting its sixth open call for data partners looking to map their patient data to the OMOP CDM. Through its first five open calls, EHDEN has created a federated data network of 140 partners across 26 countries, and it has also trained and certified 47 SMEs to assist with mapping this data. Data Partners can benefit from up to a maximum of €100 000 funding. The deadline to apply is June 14, 2022.

• All the talks and workshops from DevCon 2022 have now been uploaded to the DevCon homepage on OHDSI.org.

• Want to help provide the foundation for future advances in OHDSI global research, and receive some benefits for your company in return? Check out the OHDSI Sponsorship homepage, which includes the community call presentation from George Hripcsak.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2022.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase

Oct. 15 – Tutorial: Information | Registration

Oct. 15-16 – Workgroup Activities: Information | Registration

2022 OHDSI European Symposium

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Video Presentations

Debate 1: Phenotype Development: One-size-fits-all vs. Tailored-per-databases (Shoaibi vs. Golozar)

Debate 2: Study Diagnostics: Nice-to-have vs. Essential requirements (Schuemie vs. Prieto-Alhambra)

The May 10 Community Call featured three Mother’s Day-themed conversations, facilitated by members of our community. There were discussions around clinical research opportunities, community building and data standards, and they were meant to be open conversations to address challenges within our community and/or the healthcare field.

The three discussions (all of which are posted below) and facilitators were:

Clinical Research Opportunities: Brainstorm on maternal health
– Alison Callahan, Research Scientist, Stanford Center for Biomedical Informatics
 – Ru-fong Cheng, Senior Medical Director, Women’s Health, Office of the Chief Medical Officer, Johnson & Johnson
 – Noémie Elhadad, Associate Professor of Biomedical Informatics; Vice Chair, Research, Columbia Department of Biomedical Informatics

How can OHDSI support collaborator mothers to advance their personal and professional development?
– Rupa Makadia, Associate Director, Epidemiology Analytics, Janssen Research and Development
 – Sarah Seager, Director of Data Science, OMOP at IQVIA

Recommended best practices for modeling pregnancy episodes and mother-child linkage
– Jill Hardin, Associate Director, Epidemiology Analytics, Janssen Research and Development
 – Mui Van Zandt, VP & GM Real World Data & Tech, IQVIA 

Community Updates

• Congratulations to the team of Fatemeh Amrollahi, Supreeth P Shashikumar, Angela Meier, Lucila Ohno-Machado, Shamim Nemati, and Gabriel Wardi on the publication of Inclusion of social determinants of health improves sepsis readmission prediction models in JAMIA.

• Registration is now open for workgroup activities and meetings during the weekend of the 2022 OHDSI Global Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. Check out this page for descriptions and times of all meetings, and then register for any meetings you would like to join (these meetings are free, but registration is important because this will be first-come, first-served due to room capacity).

• All the talks and workshops from DevCon 2022 have now been uploaded to the DevCon homepage on OHDSI.org.

• Last week’s APAC Community Call included a presentation from Gowtham Rao on how to take advantage of the cohort diagnostics tool using one of the ongoing APAC studies as an example. You can find the recording on the APAC Community page.

• It was also announced on the last APAC call that the 2022 OHDSI APAC Symposium will be held Nov. 12-13 in Taipei, Taiwan. There will be both an on-site and virtual component to this event. Please follow the APAC Community page for more information.

• The latest OHDSI newsletter is now available, and it includes all the key information from DevCon, links to 10 community publications from April, details on the Sponsorship Program and other updates. If you don’t receive the monthly newsletter, you can subscribe to it here.

• Are you running a network study and seeking collaboration or data partners? Our May 24 community call will be focused on Open Studies, and we are looking for presenters. If you would like to join this call, please contact Craig Sachson at sachson@ohdsi.org.

• Want to help provide the foundation for future advances in OHDSI global research, and receive some benefits for your company in return? Check out the OHDSI Sponsorship homepage, which includes the community call presentation from George Hripcsak.

Openings

• Dani Prieto-Alhambra and his team at Oxford are recruiting a Database Programmer to join the team. This position will contribute to the standardization and curation of large real world data from the UK and collaborate with the OHDSI, EHDEN and OPTIMA Oncology teams. More information and the application link are available here. The application deadline is May 23, 2022.

• Peter Reinbeek and the Erasmus Medical Center team shared an opening for an R Programmer in Health Data Science. This position will be responsible for designing, developing, documenting, and maintaining R code that will be executed against health data that is standardized to the OMOP Common Data Model. More information and the application link are available here.

• As mentioned by Sally Baxter and Kerry Goetz during a recent community call, the National Eye Institute is looking for a DATA Scholar to develop a strategy and lead community consensus building to improve ocular health care through data standardization. Among other responsibilities, this person will build on community expertise of the OMOP CDM to advance standard representation of ocular concepts. More information is available here.

• Cynthia Sung shared a recent summer internship opportunity in the Bill & Melinda Gates Medical Research Institute. One internship of potential interest to the community is seeking a candidate in the areas of computational biology, computer science or bioengineering major who is proficient in coding in SQL and R or Python to transform Tuberculosis clinical trial data into the OMOP CDM. More information and an application link are available here.

• Daniel Smith shared a recent opening at Emory University in Atlanta for an Informatics Analyst; this position will provide OMOP support for Winship Data and Winship Discovery projects. You can learn more about this project and apply here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

Oct. 15-16 — Workshop Activities: Information | Registration

2022 OHDSI European Symposium

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

Community Updates

Video Presentations

Clinical Research Opportunities: Brainstorm on maternal health (Alison Callahan, Ru-fong Cheng, Noémie Elhadad)

How can OHDSI support collaborator mothers to advance their personal/professional development? (Rupa Makadia, Sarah Seager)

Recommended best practices for modeling pregnancy episodes and mother-child linkage (Jill Hardin, Mui Van Zandt)

The May 3 Community Call focused on the DARWIN EU Initiative, as well as how the OHDSI community can impact this new push towards using real-world evidence to impact healthcare.

The vision of DARWIN EU is to give the European Medicines Agency and national competent authorities in EU Member States access to valid and trustworthy real-world evidence, for example on diseases, patient populations, and the use, safety and effectiveness of medicines, including vaccines, throughout the lifecycle of a medicinal product.

The Erasmus Medical Center has earned the contract as the coordinating center for DARWIN EU. Peter Rijnbeek, Head of the Department of Medical Informatics at Erasmus Medical Center, led this presentation about the DARWIN EU mission and five-year plan, the role of the coordinating center, and how OHDSI tools and standards can and will impact this initiative.

Community Updates

• Congratulations to the team of Anna Ostropolets, Xintong Li, Rupa Makadia, Gowtham Rao, Peter Rijnbeek, Talita Duarte-Salles, Anthony Sena, Azza Shaoibi, Marc Suchard, Patrick Ryan, Daniel Prieto-Alhambra and George Hripcsak on the publication of Factors Influencing Background Incidence Rate Calculation: Systematic Empirical Evaluation Across an International Network of Observational Databases in Frontiers of Pharmacology.

• Congratulations to the team of Juan Quiroz, Tim Chard, Zhisheng Sa, Angus Ritchie, Louisa Jorm and Blanca Gallego on the publication of Extract, transform, load framework for the conversion of health databases to OMOP in PLOS One.

• All the talks and workshops from DevCon 2022 have now been uploaded to the DevCon homepage on OHDSI.org. A big announcement from DevCon was the formation of the Khieron Contributor Cohort, which will help onboard and mentor open-source developers in the community. If you are interested in joining the effort, please fill out this application; the deadline is THIS FRIDAY, May 6.

• This week’s APAC Community Call (May 5 in the Eastern Hemisphere, May 4 in the Western Hemisphere) will include a presentation from Gowtham Rao, who will present how to take advantage of the cohort diagnostics tool using one of the ongoing APAC studies as an example. You can get the call invitation by joining the APAC Workgroup, or you can find the link or access the recording afterwards on the APAC Community page.

• The latest OHDSI newsletter is now available, and it includes all the key information from DevCon, links to 10 community publications from April, details on the Sponsorship Program and other updates. If you don’t receive the monthly newsletter, you can subscribe to it here.

• Are you running a network study and seeking collaboration or data partners? Our May 24 community call will be focused on Open Studies, and we are looking for presenters. If you would like to join this call, please contact Craig Sachson at sachson@ohdsi.org.

• Want to help provide the foundation for future advances in OHDSI global research, and receive some benefits for your company in return? Check out the OHDSI Sponsorship homepage, which includes the community call presentation from George Hripcsak.

Openings

• Dani Prieto-Alhambra and his team at Oxford are recruiting a Database Programmer to join the team. This position will contribute to the standardization and curation of large real world data from the UK and collaborate with the OHDSI, EHDEN and OPTIMA Oncology teams. More information and the application link are available here. The application deadline is May 23, 2022.

• Peter Reinbeek and the Erasmus Medical Center team shared an opening for an R Programmer in Health Data Science. This position will be responsible for designing, developing, documenting, and maintaining R code that will be executed against health data that is standardized to the OMOP Common Data Model. More information and the application link are available here.

• As mentioned by Sally Baxter and Kerry Goetz during a recent community call, the National Eye Institute is looking for a DATA Scholar to develop a strategy and lead community consensus building to improve ocular health care through data standardization. Among other responsibilities, this person will build on community expertise of the OMOP CDM to advance standard representation of ocular concepts. More information is available here.

• Cynthia Sung shared a recent summer internship opportunity in the Bill & Melinda Gates Medical Research Institute. One internship of potential interest to the community is seeking a candidate in the areas of computational biology, computer science or bioengineering major who is proficient in coding in SQL and R or Python to transform Tuberculosis clinical trial data into the OMOP CDM. More information and an application link are available here.

• Daniel Smith shared a recent opening at Emory University in Atlanta for an Informatics Analyst; this position will provide OMOP support for Winship Data and Winship Discovery projects. You can learn more about this project and apply here.

2022 OHDSI Symposium

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs

Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

2022 OHDSI European Symposium

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

DARWIN EU | Community Updates

Video Presentation

The April 26 Community Call, focused on the state of the OHDSI open-source community, and it included a recap on the first OHDSI DevCon, held April 22. We also heard about a new opportunity in open-source development that was announced during the State of the Community presentation (more on this below).

We heard from the following leaders in our open-source community:

• Lee Evans (Owner • LTS Computing LLC) 
• Martijn Schuemie (Research Fellow, Epidemiology Analytics • Janssen Research and Development)
• Paul Nagy (Associate Professor • Johns Hopkins School of Medicine)
• Adam Black (Data Sciences • Odysseus Data Services)

Community Updates

• Congratulations to the team of Yilu Fang, Betina Idnay, Yingcheng Sun, Hao Liu, Zhehuan Chen, Karen Marder, Hua Xu, Rebecca Schnall, and Chunhua Weng on the publication of Combining human and machine intelligence for clinical trial eligibility querying in JAMIA.

• Congratulations to the team of Katie Bradwell, Jacob Wooldridge, Benjamin Amor, Tellen Bennett, Adit Anand, Carolyn Bremer, Yun Jae Yoo, Zhenglong Qian, Steven Johnson, Emily Pfaff, Andrew Girvin, Amin Manna, Emily Niehaus, Stephanie Hong, Xiaohan Tanner Zhang, Richard Zhu, Mark Bissell, Nabeel Qureshi, Joel Saltz, Melissa Haendel, Christopher Chute, Harold Lehmann, and Richard Moffitt (on behalf of the N3C Consortium) on the publication of Harmonizing units and values of quantitative data elements in a very large nationally pooled electronic health record (EHR) dataset in JAMIA.

• Congratulations to the team of Kristina Bardenheuer, Michel Van Speybroeck, Clare Hague, Enkeleida Nikai, and Martin Price on the publication of Haematology Outcomes Network in Europe (HONEUR) – a collaborative, interdisciplinary platform to harness the potential of Real-World Data in hematology in the European Journal of Haematology.

• OHDSI DevCon 2022 was a success last Friday, with more than 100 people joining for a series of workshops, talks and an impressive final panel discussion. All the talks will be loaded to the DevCon homepage on OHDSI.org, but both the State of the Community presentation by Adam Black and Paul Nagy, as well as the Keynote Address by Martijn Schuemie, are currently on the page. A big announcement from DevCon was the formation of the Khieron Contributor Cohort, which will help onboard and mentor open-source developers in the community. If you are interested in joining the effort, please fill out this application.

• Want to help provide the foundation for future advances in OHDSI global research, and receive some benefits for your company in return? Check out the OHDSI Sponsorship homepage, which includes the community call presentation from George Hripcsak.

• The most recent APAC Community Call featured APAC Studies quarterly updates. You can access the recording afterwards, on the APAC Community page.

• Are you running a network study and seeking collaboration or data partners? Our May 24 community call will be focused on Open Studies, and we are looking for presenters. If you would like to join this call, please contact Craig Sachson at sachson@ohdsi.org.

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs
Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Openings

• Peter Reinbeek and the Erasmus Medical Center team shared an opening for an R Programmer in Health Data Science. This position will be responsible for designing, developing, documenting, and maintaining R code that will be executed against health data that is standardized to the OMOP Common Data Model. More information and the application link are available here. The application deadline is this Wednesday, April 27.

• Dani Prieto-Alhambra and his team at Oxford are recruiting a Database Programmer to join the team. This position will contribute to the standardization and curation of large real world data from the UK and collaborate with the OHDSI, EHDEN and OPTIMA Oncology teams. More information and the application link are available here. The application deadline is May 23, 2022.

• As mentioned by Sally Baxter and Kerry Goetz on last week’s community call, the National Eye Institute is looking for a DATA Scholar to develop a strategy and lead community consensus building to improve ocular health care through data standardization. Among other responsibilities, this person will build on community expertise of the OMOP CDM to advance standard representation of ocular concepts. More information is available here.

Slides

Community Updates

Video Presentation

The April 19 OHDSI Community Call featured a new set of workgroup updates, including an introduction of a brand new workgroup (Eye Care and Vision Research):

• Eye Care and Vision Research (Sally Baxter, Assistant Professor, Division Chief for Ophthalmology Informatics and Data Science, UC San Diego)
• FHIR and OMOP (Christian Reich, Vice President, RWE Systems • IQVIA)
• Oncology (Asieh Golozar, VP, Global Head of Data Science • Odysseus Data Services)
• Steering Group (Jody-Ann McLeggon • Program Manager, Columbia University)

Community Updates

• Congratulations to the team of Henrik John, Jan Kors, Jenna Reps, Patrick Ryan, and Peter Rijnbeek on the publication of Logistic regression models for patient-level prediction based on massive observational data: Do we need all data? in the International Journal of Medical Informatics.

• Congratulations to the team of Yilu Fang, Betina Idnay, Yingcheng Sun, Hao Liu, Zhehuan Chen, Karen Marder, Hua Xu, Rebecca Schnall, and Chunhua Weng on the publication of Combining human and machine intelligence for clinical trial eligibility querying in JAMIA.

• Curious about the new OHDSI Sponsorship program that was announced last week, and how you can help support the community’s global research journey? Check out the OHDSI Sponshorship homepage, which includes the community call presentation from George Hripcsak.

• The next APAC Community Call will be held Thursday, April 21 (Wednesday night in the Western Hemisphere) and will provide APAC Studies quarterly updates. You can get the link for the call, or access the recording afterwards, on the APAC Community page.

• Are you running a network study and seeking collaboration or data partners? Our May 24 community call will be focused on Open Studies, and we are looking for presenters. If you would like to join this call, please contact Craig Sachson at sachson@ohdsi.org.

• The Open-Source Community is hosting the first OHDSI Dev Con on April 22 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. You can register for the event now. 

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs
Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

Eye Care & Vision Research | FHIR & OMOP | Oncology | Steering Group | Community Updates

Videos

Eye Care & Vision Research (Sally Baxter and Kerry Goetz)

FHIR & OMOP (Christian Reich)

Oncology (Asieh Golozar)

Steering Group (Jody-Ann McLeggon)

George Hripcsak, Chair and Vivian Beaumont Allen Professor of Biomedical Informatics at Columbia University, discussed the many ways Columbia DBMI supports OHDSI, and he shares why it will be important to support the coordinating center in the future, as well as what benefits can come from your support. 

Community Updates

• Congratulations to the team of Berta Raventós, Andrea Pistillo, Carlen Reyes, Sergio Fernández-Bertolín, Maria Aragón, Anna Berenguera, Constanza Jacques-Aviñó, Laura Medina-Perucha, Edward Burn, and Talita Duarte-Salles on the publication of Impact of the COVID-19 pandemic on diagnoses of common mental health disorders in adults in Catalonia, Spain: a population-based cohort study in BMJ Open.

• Congratulations to the team of Tae-Hoon Kim, SiHyeong Noh, Youe Ree Kim, ChungSub Lee, Ji Eon Kim, Chang-Won Jeong, and Kwon-Ha Yoon on the publication of Development and validation of a management system and dataset quality assessment tool for the Radiology Common Data Model (R_CDM): A case study in liver disease in the International Journal of Medical Informatics.

• Based on George Hripcsak’s presentation, OHDSI has created both Sponsorship Program and Sponsors pages on the website. Please check them out and see how you can support OHDSI’s growth while receiving several benefits for your organization.

• The Open-Source Community is hosting the first OHDSI Dev Con on April 22 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. You can register for the event now.

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs
Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

OHDSI Coordinating Center | Community Updates

Video

Patrick Ryan led the OHDSI community in a game of “Name That Result” (a distant relative of the old Name That Tune game show) where eight contestants were able to showcase all the ways they could get from data to evidence using the OMOP CDM and OHDSI tools. This one was decided on the final question!

Thank you to Michael Cook, Stephanie Hong, Kristin Kostka, Martin Lavallee, Filip Malkovic, Maxim Moinat, Jose Posada, and Katherine Simon for their insights and spirited competition in this game!

Community Updates

• Congratulations to the team of Chongliang Luo, Md Nazmul Islam, Natalie Sheils, John Buresh, Jenna Reps, Martijn Schuemie, Patrick Ryan, Mackenzie Edmondson, Rui Duan, Jiayi Tong, Arielle Marks-Anglin, Jiang Bian, Zhaoyi Chen, Talita Duarte-Salles, Sergio Fernández-Bertolín, Thomas Falconer, Chungsoo Kim, Rae Woong Park, Stephen Pfohl, Nigam Shah, Andrew Williams, Hua Xu, Yujia Zhou, Ebbing Lautenbach, Jalpa Doshi, Rachel Werner, David Asch, and Yong Chen on the publication of DLMM as a lossless one-shot algorithm for collaborative multi-site distributed linear mixed models in Nature Communications.

• Congratulations to the team of Seok Kim, Ji-In Bang, Dachung Boo, Borham Kim, In Young Choi, SooJeong Ko, Ie Ryung Yoo, Kwangsoo Kim, Junmo Kim, YoungHwan Joo, Hyun Gee Ryoo, Jin Chul Paeng, Jung Mi Park, Woncheol Jang, Byungwon Kim, Yangha Chung, Dongyoon Yang, Sooyoung Yoo, and Ho-Young Lee on the publication of Second primary malignancy risk in thyroid cancer and matched patients with and without radioiodine therapy analysis from the observational health data sciences and informatics in European Journal of Nuclear Medicine and Molecular Imaging.

• Both the presentations and slides from the recent community call session on Reproducibility are now available here. This session was led by Anna Ostropolets, Martijn Schemie and Asieh Golozar, and focused on the OHDSI2021 Reproducibility Challenge, how to design reproducible studies, and the Reproducibility Service at the Roux Institute.

• The April edition of the OHDSI Newsletter is now available, and it includes reports on the CDM Workshop, DevCon, and the OHDSI2022 Tutorial, as well as other community updates, links to publications and presentations, and plenty more. If you aren’t already subscribing to the newsletter, you can do so here.

• The Open-Source Community is hosting the first OHDSI Dev Con on April 22 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. You can register for the event now.

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs
Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage. 

Slides

Community Updates

Video

The March 29 OHDSI Community Call focused on reproducibility, and three leaders in the community shared presentations on this topic. 

– The 2021 OHDSI Reproducibility Challenge (Anna Ostropolets)
– Developing Reproducible Studies (Martijn Schuemie)
– The OHDSI Reproducibility Service (Asieh Golozar)

Community Updates

• Congratulations to the team of Yuan Lu, Mui Van Zandt, Yun Liu, Jing Li, Xialin Wang, Yong Chen, Zhengfeng Chen, Jaehyeong Cho, Sreemanee Raaj Dorajoo, Mengling Feng, Min-Huei Hsu, Jason C. Hsu, Usman Iqbal, Jitendra Jonnagaddala, Yu-Chuan Li, Siaw-Teng Liaw, Hong-Seok Lim, Kee Yuan Ngiam, Phung-Anh Nguyen, Rae Woong Park, Nicole Pratt, Christian Reich, Sang Youl Rhee, Selva Muthu Kumaran Sathappan, Seo Jeong Shin, Hui Xing Tan, Seng Chan You, Xin Zhang, Harlan M. Krumholz, Marc A. Suchard, and Hua Xu on the publication of Analysis of Dual Combination Therapies Used in Treatment of Hypertension in a Multinational Cohort in JAMA Network Open.

This is an especially exciting paper, as it is the first to come out of the OHDSI Asia-Pacific (APAC) Workgroup. The APAC team leads a bi-weekly community call, and each is recorded. Last week’s session included a presentation from Christian Reich about the FHIR-OMOP partnership. You can see that recording and get both the link and themes for upcoming calls at the APAC homepage.

• Congratulations to both Aki Nishimura and Marc Suchard on the publication of Prior-preconditioned conjugate gradient method for accelerated Gibbs sampling in ‘large n & large p’ Bayesian sparse regression in the Journal of the American Statistical Association.

• Registration has opened for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center. The main conference will be held Friday, Oct. 14, while a full-day tutorial (An Introductory Journey from Data to Evidence) will be held Saturday, Oct. 15. There will be several workgroup activities between Oct. 15-16 as well. Here are several important links for #OHDSI2021.

Full Symposium: Homepage | Weekend Room Block | FAQs
Oct. 14 – Main Conference: Information | Registration | Collaborator Showcase
Oct. 15 – Tutorial: Information | Registration

• The Open-Source Community is hosting the first OHDSI Dev Con on April 22 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. The full agenda has been added. You can register for the event now.

• The recent presentation on “The OHDSI Vocabulary Journey” from Michael Kallfelz, Christian Reich and Patrick Ryan, including both the video and slides from the community call, as well as the introduction from the Vocabulary chapter in the Book of OHDSI, is available here.

• The OMOP CDM Workshop that was held earlier this month has been put together into a single video tutorial, which you can find here. This page also has all the slides from the workshop, as well as the CDM introductory text from the Book of OHDSI.

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

Reproducibility Challenge | Designing Reproducible Studies | OHDSI Reproducibility Service | Community Updates

Video Presentations

Reproducibility Challenge (Anna Ostropolets)

Designing Reproducible Studies (Martijn Schuemie)

The OHDSI Reproducibility Service (Asieh Golozar)

The March 22 OHDSI Community Call provided an in-depth look at the OHDSI vocabulary, from how it is developed, to how it can be utilized, and where it should grow from here. Three leaders from the vocabulary workgroup joined to present a trio of topics for this session (see below). 

– A peek into the OHDSI vocabulary engine room (Michael Kallfelz)
– Fun things you can learn with the OHDSI standardized vocabularies (Patrick Ryan)
– Time for reflection • Where are we? Where should we be? (Christian Reich)

Community Updates

• Congratulations to the team of JungHyun Byun, Dong Yun Lee, Chang-Won Jeong, Yerim Kim, Hak Young Rhee, Ki Won Moon, Jeongwon Heo, Yoonki Hong, Woo Jin Kim, Seung-Joo Nam, Hoon Sung Choi, Ji In Park, In Kook Chun, So Hyeon Bak, Kyoungyul Lee, Gi Hwan Byeon, Kyoung Lae Kim, Jeong-Ah Kim, Young Joo Park, Jeong Hyun Kim, Eun ju Lee, Sang-Ah Lee, Sung Ok Kwon, Sang-Won Park, Payam Hosseinzadeh Kasani, Jung-Kyeom Kim, Yeshin Kim, Seongheon Kim and Jae-Won Jang on the publication of Analysis of treatment pattern of anti-dementia medications in newly diagnosed Alzheimer’s dementia using OMOP CDM in Scientific Reports.

• Congratulations to the team of Kristin Kostka, Talita Duarte-Salles, Albert Prats-Uribe, Anthony G Sena, Andrea Pistillo, Sara Khalid, Lana YH Lai, Asieh Golozar, Thamir M Alshammari, Dalia M Dawoud, Fredrik Nyberg, Adam B Wilcox, Alan Andryc, Andrew Williams, Anna Ostropolets, Carlos Areia, Chi Young Jung, Christopher A Harle, Christian G Reich, Clair Blacketer, Daniel R Morales, David A Dorr, Edward Burn, Elena Roel, Eng Hooi Tan, Evan Minty, Frank DeFalco, Gabriel de Maeztu, Gigi Lipori, Hiba Alghoul, Hong Zhu, Jason A Thomas, Jiang Bian, Jimyung Park, Jordi Martínez Roldán, Jose D Posada, Juan M Banda, Juan P Horcajada, Julianna Kohler, Karishma Shah, Karthik Natarajan, Kristine E Lynch, Li Liu, Lisa M Schilling, Martina Recalde, Matthew Spotnitz, Mengchun Gong, Michael E Matheny, Neus Valveny, Nicole G Weiskopf, Nigam Shah, Osaid Alser, Paula Casajust, Rae Woong Park, Robert Schuff, Sarah Seager, Scott L DuVall, Seng Chan You, Seokyoung Song, Sergio Fernández-Bertolín, Stephen Fortin, Tanja Magoc, Thomas Falconer, Vignesh Subbian, Vojtech Huser, Waheed-Ul-Rahman Ahmed, William Carter, Yin Guan, Yankuic Galvan, Xing He, Peter R Rijnbeek, George Hripcsak, Patrick B Ryan, Marc A Suchard, and Daniel Prieto-Alhambra on the publication of Unraveling COVID-19: A Large-Scale Characterization of 4.5 Million COVID-19 Cases Using CHARYBDIS in Clinical Epidemiology.

• We are thrilled to announce that registration for the 2022 OHDSI Symposium, which will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center, is now open!

The main conference will be held Friday, Oct. 14, while a full-day tutorial will be held Saturday, Oct. 15. Other community activities, mainly focused on OHDSI workgroups, will be held both Oct. 15 and Oct. 16. The OHDSI2022 homepage has more information, as well as registration links to both the conference and the tutorial (these are separate events and each requires its own registration), information on the collaborator showcase, hotel room blocks, and plenty more.

Direct registration is available for both the main conference and the full-day tutorial. Please continue to check our symposium homepage and our social platforms, and join the weekly OHDSI community calls, for more information.

• The Open-Source Community is hosting the first OHDSI Dev Con on April 12 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. You can register for the event now.

• The OMOP CDM Workshop that was held over the last two OHDSI Community Calls has been put together into a single video tutorial, which you can find here. This page also has all the slides from the workshop, as well as the CDM introductory text from the Book of OHDSI.

• The next APAC Community Call will be held this Wednesday/Thursday based on your time zone. Christian Reich will present on the OMOP/FHIR collaboration during this call. You can access these calls by joining the Asia-Pacific (APAC) Workgroup in Teams.

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

OHDSI Vocabulary Journey | Community Updates

Video Presentation

Clair Blacketer and members of the CDM Workgroup put together the second of a two-part CDM Workshop session during the March 15 OHDSI Community Call. Following an introduction by Clair, there were specific talks on the following topics:

• Vocabulary Mapping and Usagi (Melanie Philofsky)
• Data Quality (Clair Blacketer)
• ACHILLES (Anthony Molinaro)
• Putting It All Together (Frank DeFalco) 

Part 1 of this workshop was held during the March 8 Community Call; you can watch that video here: https://youtu.be/y7CXONEMLoI.

Community Updates

• Congratulations to the team of Matthew Spotnitz, Anna Ostropolets, Victor G. Castanob, Karthik Natarajan, Genna Waldman, Michael Argenziano, Ruth Ottman, George Hripcsak, Hyunmi Choi, and Brett Youngerman for the publication of Patient characteristics and antiseizure medication pathways in newly diagnosed epilepsy: Feasibility and pilot results using the common data model in a single-center electronic medical record database recently in Epilepsy & Behavior.

• The 2022 OHDSI Symposium will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center in Bethesda, Md. The main symposium will be held Friday, Oct. 14, while the next two weekend will include community activities. More information about the weekend, including registration and the collaborator showcase, will be shared when available.

• The Open-Source Community is hosting the first OHDSI Dev Con on April 12 (8 am – 12 pm ET) as a way of accepting and mentoring new contributors to our environment. Organized by Paul Nagy and Adam Black on behalf of the Open-Source Community Workgroup, the event will include multiple workshops, talks and a panel discussion to both welcome and engage both current and future developers within OHDSI. You can register for the event now.

• Phenotype Phebruary may have ended, but the conversations still continue in the OHDSI forums. All of the “phun phacts” that were shared during our community calls have been put together in a single video, so you can learn about all 29 phenotypes discussed during the month. All daily threads can be found on the Phenotype Phebruary homepage.

• Our colleagues within EHDEN are opening their fourth and final call for SMEs to apply for training and certification on converting health data from various formats to the OMOP common data model. Currently, EHDEN has 47 SMEs across 19 European nations working on the EHDEN data network, which includes 140 data partners across 16 countries. You can see the fill list of EHDEN-certified SMEs, as well the EHDEN data partner network.

• Dani Prieto-Alhambra recently shared that his team at Oxford is accepting applications for an IT System Manager and Database Administrator. The deadline for application is April 11, 2022. For more registration and to apply, please visit the Job Details page.

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

CDM Workshop | Community Updates

Video

CDM Workshop (Clair Blacketer, Melanie Philofsky, Anthony Molinaro and Frank DeFalco)

The March 8 OHDSI community call featured Part 1 of our two-week OMOP CDM Workshop. We were excited to have four representatives from our Common Data Model Workgroup lead this session:  

• Clair Blacketer, Associate Director, Janssen Research & Development
• Frank DeFalco, Director, Observational Health Data Analytics, Janssen Research & Development
• Kristin Kostka, Director of the OHDSI Center, Roux Institute, Northeastern University
• Maxim Moinat, Data Engineer/Software Developer, The Hyve

Prior to the CDM Workshop, Paul Nagy presented the newly developed Engine of Impact Project (EOI), a dashboard that allows for regular monitoring of the health and progress of the OHDSI community. Videos/slides for both the CDM Workshop and EOI Project are below.

Community Updates

• The 2022 OHDSI Symposium will be held Oct. 14-16 at the Bethesda North Marriott Hotel & Conference Center in Bethesda, Md. The main symposium will be held Friday, Oct. 14, while the next two weekend will include community activities. More information about the weekend, including registration and the collaborator showcase, will be shared when available.

• The latest edition of The Journey newsletter is now available. This edition includes a full review of Phenotype Phebruary, a look at the DARWIN EU announcement by the European Medicines Agency, publications and presentations, and much more. If you don’t get The Journey in your email, please subscribe here.

• 2021 OHDSI Titan Award winner Maxim Moinat was profiled in our latest Collaborator Spotlight. Learn more about Maxim’s background, his work with open-source tools, EHDEN, the upcoming DARWIN EU initiative, and much more.

• The next CBER BEST Seminar will be held Wednesday, April 27, at 11 am ET. Eric Tchetgen Tchetgen (Luddy Family President’s Distinguished Professor, the Wharton School of the University of Pennsylvania) will present his work on “Addressing Selection and Confounding Bias in Test-Negative Study Designs for Flu and COVID-19 Monitoring.” You can register for this seminar here.

• If you missed Nicole Pratt’s CBER BEST Seminar on “Evaluating Use of Methods for Adverse Event Under Surveillance for Vaccines,” you can watch it now.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

Slides

CDM Workshop | EOI Project | Community Updates

Videos

CDM Workshop (Clair Blacketer, Frank DeFalco, Kristin Kostka, Maxim Moinat)

Engine of Impact Project (Paul Nagy)

The March 1 OHDSI community call included final reflections on Phenotype Phebruary, and then hosted breakout discussions on what is happening around the three main OHDSI focuses of characterization, estimation and prediction, and how do we as a community collaborate to accomplish our 2022 OKRs. 

• Patrick Ryan will led the final update on Phenotype Phebruary, which you can join in the daily conversations at the OHDSI forums or at the event homepage
• Anthony Sena and Aniek Markus moderated a conversation in work around Characterization
• Marc Suchard moderated a conversation in work around Estimation
• Jenna Reps and Ross Williams moderated a conversation in work around Prediction

Community Updates

• As announced at our last community call, the 2022 OHDSI U.S. Symposium will be held Oct. 14-16, with the main symposium set for Oct. 14. We will have more information on the event in the coming weeks, but please save those dates for #OHDSI2022.

• Phenotype Phebruary completed its final week, and it has been amazing to watch the activity ongoing on so many threads discussing different phenotypes developments & evaluation. Each daily post is linked on this page on OHDSI.org: https://www.ohdsi.org/phenotype-phebruary/. You can find each phenotype topic and post from the last week below; please check them out and continue the conversations. Thank you to Asieh Golozar, Rupa Makadia, Jill Hardin, Erica Voss, Tiffany Callahan, Juan Banda, Anna Ostropolets, Claudia Pulgarin, Marcela Rivera, and David Vizcaya for leading these discussions

Feb. 21 • Prostate Cancer
Feb. 22 • HIV
Feb. 23 • Hidradenitis Suppurativa
Feb. 24 • Anaphylaxis
Feb. 25 • Depression
Feb. 26 • Non-Small-Cell Lung Cancer
Feb. 27 • Drug-Induced Liver Injury
Feb. 28 • Severe Visual Impairment and Blindness
Bonus • Acute Kidney Injury

• Congratulations to the team of Edward Burn, Xintong Li, Kristin Kostka, Henry Morgan Stewart, Christian Reich, Sarah Seager, Talita Duarte-Salles, Sergio Fernandez-Bertolin, María Aragón, Carlen Reyes, Eugenia Martinez-Hernandez, Edelmira Marti, Antonella Delmestri, Katia Verhamme, Peter Rijnbeek, Scott Horban, Daniel Morales, and Daniel Prieto-Alhambra on the recent publication of Background rates of five thrombosis with thrombocytopenia syndromes of special interest for COVID-19 vaccine safety surveillance: Incidence between 2017 and 2019 and patient profiles from 38.6 million people in six European countries in Pharmacoepidemiology and Drug Safety.

• Congratulations to the team of Emily Pfaff, Melissa Haendel, Kristin Kostka, Adam Lee, Emily Niehaus, Matvey Palchuk, Kellie Walters, and Christopher Chute on the recent publication of Ensuring a safe(r) harbor: Excising personally identifiable information from structured electronic health record data in the Journal of Clinical and Translational Science.

• Clair Blacketer led Part 2 of a CDM Workshop for the Asia-Pacific (APAC) community as part of the most recent APAC Community Call (see video here). Clair will lead a two-part workshop on the global community call over the next two weeks.

• Curious about the Objectives & Key Results (OKRs) set by our various workgroups. These were presented at a recent meeting between workgroup leads, and they have been posted to the new OHDSI Workgroups page. If you want to join any of our workgroups, please fill out this form.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The #OHDSISocialShowcase wraps up this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: OMOP-CDM ETLs with Dask and Prefect
Tuesday: Learning under constraints with EXPLORE
Wednesday: Estimating Model Performance on External Datasets from Their Limited Statistical Characteristics: Application to 3-Year Surgery Risk in Ulcerative Colitis

Slides

Phenotype Phebruary Report | Prediction Breakout | Community Updates

Videos

Phenotype Phebruary Final Report (Patrick Ryan)

Characterization Discussion (moderated by Aniek Markus and Anthony Sena)

Estimation Discussion (moderated by Marc Suchard)

Prediction Discussion (moderated by Jenna Reps and Ross Williams)

The Feb. 22 OHDSI community call featured a trio of presentations:

Community Updates

• Phenotype Phebruary is heading into the final week, and we currently have 20 interactive forum threads ongoing discussing different phenotypes developments & evaluation. Each daily post will be linked on this page on OHDSI.org: https://www.ohdsi.org/phenotype-phebruary/. You can find each phenotype topic and post from the last week below; please check them out and continue the conversations. Thank you to Azza Shoaibi, Gowtham Rao, Adam Black and Evan Minty for leading these discussions

Feb. 14 • Hypertension (Video Description)
Feb. 15 • Acute Myocardial Infarction
Feb. 16 • Heart Failure
Feb. 17 • Cardiomyopathy
Feb. 18 • Multiple Sclerosis
Feb. 19 • Triple Negative Breast Cancer
Feb. 20 • Pulmonary Hypertension
Feb. 21 • Prostate Cancer

• The next CBER Best Seminar will be provided by a veteran collaborator within the OHDSI community. Nicole Pratt (Professor, University of South Australia) will present on “Evaluating Use of Methods for Adverse Event Under Surveillance For Vaccines” at 11 am ET this Wednesday, Feb. 23. This seminar is free and open to the public; you can register here.

• The next Asia-Pacific (APAC) Community Call will be held Wednesday, March 23 at 10 pm ET. Clair Blacketer will provide part 2 of the first CDM Workshop of 2022. If you missed the first part, you can watch that recording here.

• Curious about the Objectives & Key Results (OKRs) set by our various workgroups? These were presented at a recent meeting between workgroup leads, and they have been posted to the new OHDSI Workgroups page. If you want to join any of our workgroups, please fill out this form.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage. 

• Our collaborators at Janssen Research & Development recently posted a new position for Manager, Observational Health Data Analytics. You can find a job description and application link here.

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: Attention based deep neural networks in patient level prediction
Tuesday: REDCap2OMOP: A platform for ETLing REDCap projects into the OMOP CDM
Wednesday: Trends in the development and validation of patient-level prediction models using electronic health record data: a systematic review
Thursday: Short-term mortality in patients undergoing colorectal cancer surgery: A prediction study
Friday: Proof-of-concept model targeting patient-level prediction of 90-day mortality after colorectal cancer surgery kickstarts OHDSI journey

Slides

ATLAS WG | Medical Imaging WG | Phenotype Phebruary | Community Updates

Video Presentations

ATLAS WG (Anthony Sena)

Medical Imaging WG (Paul Nagy)

Phenotype Phebruary (Patrick Ryan)

The Feb. 8 OHDSI community call featured a trio of presentations:

Community Updates

• Congratulations to Peter Rijnbeek and all of our collaborators at the Erasmus University Medical Center for being awarded a contract to establish the Coordination Center for the Data Analysis and Real World Interrogation Network (DARWIN EU). As noted in this EHDEN press release, “DARWIN EU will be able to leverage the extensive work done within the European Health Data and Evidence Network (EHDEN) project funded by the Innovative Medicines Initiative (IMI), and the Observational Health Data Sciences and Informatics (OHDSI) community.”

• Phenotype Phebruary has begun, and we have six interactive forum threads ongoing discussing different phenotypes developments & evaluation. Each daily post will be linked on this page on OHDSI.org: https://www.ohdsi.org/phenotype-phebruary/. You can find each phenotype topic and post from the last week below; please check them out and continue the conversations. Thank you to Azza Shoaibi, Gowtham Rao, Joel Swerdel, Allan Wu and Patrick Ryan for leading these discussions.

Feb 7 • Neutropenia
Feb 8 • Kidney Stones
Feb 9 • Delirium
Feb 10 • Systemic Lupus Erythematosus
Feb 11 • Suicide Attempts
Feb 12 • Parkinson’s Disease and Parkinsonism
Feb 13 • Attention Deficit Hyperactivity Disorder
Feb 14 • Hypertension

• The next CBER Best Seminar will be provided by a veteran collaborator within the OHDSI community. Nicole Pratt (Professor, University of South Australia) will present on “Evaluating Use of Methods for Adverse Event Under Surveillance For Vaccines” at 11 am ET on Wednesday, Feb. 23. This seminar is free and open to the public; you can register here. 

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: Scaling OHDSI open-source community projects, lessons learned by Oncology Work group
Tuesday: CemConnector: A RESTFul application programing interface and client library for the Common Evidence Model (CEM)
Wednesday: Disease Progression Modeling Workbench 360
Thursday: Evaluating Patient Count Vs Hospitalization Risk for Common Clinical Trial Eligibility Criteria: A Case Study for Relapsed/Refractory Lymphoma/Leukemia
Friday: Representation of investigational drugs in the OMOP CDM

Slides

CDM Workgroup | Data Quality Workgroup | Phenotype Phebruary Report | Community Updates

Video Presentations

CDM Workgroup Update (Clair Blacketer)

Data Quality Workgroup Update (Clair Blacketer)

Phenotype Phebruary Report #2 (Patrick Ryan)

The Feb. 8 OHDSI community call featured a trio of presentations:

Community Updates

• Phenotype Phebruary has begun, and we have six interactive forum threads ongoing discussing different phenotypes developments & evaluation. Each daily post will be linked on this page on OHDSI.org: https://www.ohdsi.org/phenotype-phebruary/. You can find each phenotype topic and post from the last week below; please check them out and continue the conversations.

Feb. 1 • Type 2 Diabetes Mellitus
Feb. 2 • Type 1 Diabetes Mellitus
Feb. 3 • Atrial Fibrillation
Feb. 4 • Multiple Myeloma
Feb. 5 • Alzheimer’s Disease
Feb. 6 • Hemorrhagic Events
Feb. 7 • Neutropenia

• The February 2022 edition of The Journey newsletter is now available. If you don’t the newsletter in your email, please subscribe here. What will you find in the latest edition of The Journey?

• Community Updates
• Extracting OHDSI Concepts from Clinical Narratives for COVID Presentation
• OHDSI Goals for 2022
• Recent Publications
• MORE! 

• Longtime OHDSI collaborator Jon Duke will lead a discussion on saying goodbye to manual registries with the creation of interoperable EHR based clinical registries during the next Grand Rounds at Johns Hopkins, led by Paul Nagy. This leverages the forefront of the OHDSI and FHIR communities committed to open standards and open science. This free session takes place Thursday at 12 pm ET, and you can register here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, will be held June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: Diagnostic Accuracy of Code-Based Algorithms to Identify Urinary Tract Infection in U.S. Administrative Claims Databases
Tuesday: Assessing impact on change in incidence on calibration performance across external validation
Wednesday: A journey through VA’s uptake of the OMOP common data model
Thursday: Medication dosage and exposure duration in OMOP CDM: mapping challenges
Friday: There & Back Again: Using Julia to Augment OHDSI R Packages

Slides

Healthcare Systems | Open Source Community | Phenotype Phebruary | Community Updates

Video Presentations

Healthcare Systems Special Interest Group Update (Melanie Philofsky)

Open Source Community Workgroup Introduction Announcement (Adam Black)

Phenotype Phebruary Report #1 (Patrick Ryan)

Patrick Ryan introduced a community-wide activity around developing and evaluating at least 28 phenotypes across the 28 days of February. This presentation includes a discussion on the importance of phenotypes, a closer look at OHDSI tools that can be used in developing and evaluating them, a plan for executing this initiative across the community, and a jump into the Day 1 phenotype: Type 2 Diabetes Mellitus.

Community Updates

• Congratulations to the team of Ross D. Williams, Aniek F. Markus, Cynthia Yang, Talita Duarte-Salles, Scott L. DuVall, Thomas Falconer, Jitendra Jonnagaddala, Chungsoo Kim, Yeunsook Rho, Andrew E. Williams, Amanda Alberga Machado, Min Ho An, María Aragón, Carlos Areia, Edward Burn, Young Hwa Choi, Iannis Drakos, Maria Tereza Fernandes Abrahão, Sergio Fernández-Bertolín, George Hripcsak, Benjamin Skov Kaas-Hansen, Prasanna L. Kandukuri, Jan A. Kors, Kristin Kostka, Siaw-Teng Liaw, Kristine E. Lynch, Gerardo Machnicki, Michael E. Matheny, Daniel Morales, Fredrik Nyberg, Rae Woong Park, Albert Prats-Uribe, Nicole Pratt, Gowtham Rao, Christian G. Reich, Marcela Rivera, Tom Seinen, Azza Shoaibi, Matthew E. Spotnitz, Ewout W. Steyerberg, Marc A. Suchard, Seng Chan You, Lin Zhang, Lili Zhou, Patrick B. Ryan, Daniel Prieto-Alhambra, Jenna M. Reps and Peter R. Rijnbeek on the publication of “Seek COVER: using a disease proxy to rapidly develop and validate a personalized risk calculator for COVID-19 outcomes in an international network” in BMC Medical Research Methodology.

• Congratulations to the team of Seung-Hwa Lee, Jungchan Park, Rae Woong Park, Seo Jeong Shin, Jinseob Kim, Ji Dong Sung, Dae Jung Kim, and Kwangmo Yang on the publication of “Renin-Angiotensin-Aldosterone System Inhibitors and Risk of Cancer: A Population-Based Cohort Study Using a Common Data Model” in Diagnostics. 

• The most recent Asia-Pacific (APAC) Community Call was held last week, and it featured a CDM Workshop led by Clair Blacketer. This was the first of several planned CDM Workshops for 2022, and video of this session is now available. You can also find a written Q&A from the workshop on our APAC Community page.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, has been moved to the new date of June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: Securing OHDSI on AWS for HIPAA and Research Data Management Compliance
Tuesday: Identification of treatment intent from the actual time-to-treatment distribution in prostate cancer patients
Wednesday: The concept of anchoring in observational study design and its influence
Thursday: Summarizing current evidence for the PIONEER study-a-thon: Systematic Literature Review of prostate cancer patients managed with watchful waiting
Friday: LAISDAR – A federated data network to support COVID-19 research in Rwanda

Slides

Presentation | Community Updates

Video

During our Jan. 18 community call, Dr. Hongfang Liu (Mayo Clinic) and Dr. Christopher Chute (Johns Hopkins University) led a session on Extracting OHDSI Concepts from Clinical Narratives for COVID. Following the presentation (approximately 33 minutes), there is a Q&A session. 

Community Updates

• Congratulations to co-authors ChulHyoung Park, Seng Chan You, Hokyun Jeon, Chang Won Jeong, Jin Wook Choi, and Rae Woong Park on the publication of “Development and Validation of the Radiology Common Data Model (R-CDM) for the International Standardization of Medical Imaging Data” which was recently published in the Yonsei Medical Journal.

• Congratulations to co-authors Xiangmin Ji, Guimei Cui, Chengzhen Xu, Jie Hou, Yunfei Zhang, and Yan Ren on the publication of “Combining a Pharmacological Network Model with a Bayesian Signal Detection Algorithm to Improve the Detection of Adverse Drug Events” recently in Frontiers in Pharmacology.

• Congratulations to the team of Seung-Hwa Lee, Jungchan Park, Rae Woong Park, Seo Jeong Shin, Jinseob Kim, Ji Dong Sung, Dae Jung Kim, and Kwangmo Yang on the publication of “Renin-Angiotensin-Aldosterone System Inhibitors and Risk of Cancer: A Population-Based Cohort Study Using a Common Data Model” in Diagnostics.

• Our friends in the EHDEN Project recently highlighted its many successes over the first three years of its five-year project, including harmonizing more than 500 million health records across 27 countries, developing 14 courses (and counting) in the EHDEN Academy, and plenty more. You can read that report here.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, has been moved to the new date of June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• Our Janssen collaborators recently announced an opening for two summer interns for its 2022 Observational Health Data Analytics Internship Program. Learn more about this opportunity and apply using that link.

• The #OHDSISocialShowcase continues on Wednesday this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: The VISIT_DETAIL: A Vehicle for Standard Visits
Tuesday: Leveraging APHRODITE to identify bias in statistical phenotyping algorithms
Wednesday: From type 2 diabetes diagnosis to developing complications: a multi-country approach to understanding patients journey
Thursday: Distributed Counterfactual Modeling Approach for Investigating Hospital-Associated Racial Disparities in COVID-19 Mortality
Friday: Design of a framework to detect temporal clinical event trajectories from health data standardized to the OMOP CDM

Slides

Presentation | Community Updates

Video

During our Jan. 18 community call, workgroups came together in GatherTown to discuss Objectives and Key Results (OKRs) to set for 2022. These OKRs will be evaluated quarterly at both the global community level, as well as within the individual workgroups, to measure the success our community is having, and where we need to put greater attention moving forward.

That session was not recorded; it followed our weekly community updates, which are available below.

Community Updates

• Congratulations to co-authors Daniel Morales, Anna Ostropolets, Lana Lai, Anthony Sena, Scott Duvall, Marc Suchard, Katia Verhamme,Peter Rjinbeek, Jose Posada, Waheed Ahmed, Thamer Alshammary, Heba Alghoul, Osaid Alser, Carlos Areia, Clair Blacketer, Ed Burn, Paula Casajust, Seng You, Dalia Dawoud, Asieh Golozar, Menchung Gong, Jitendra Jonnagaddala, Kristine Lynch, Michael Matheny, Evan Minty, Fredrik Nyberg, Albert Uribe, Martina Recalde, Christian Reich, Martijn Scheumie, Karishma Shah, Nigam Shah, Lisa Schilling, David Vizcaya, Lin Zhang, George Hripcsak, Patrick Ryan, Daniel Prieto-Alhambra, Talita Durate-Salles, and Kristin Kostka on the publication of “Characteristics and outcomes of COVID-19 patients with and without asthma from the United States, South Korea, and Europe” which was recently published in the Journal of Asthma.

• Congratulations to Seng Chan You and Harlan Krumholz, who recently published this commentary in Circulation: The Evolution of Evidence-Based Medicine: When the Magic of the Randomized Clinical Trial Meets Real-World Data.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, has been moved to the new date of June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The latest edition of “The Journey” OHDSI newsletter is now available, and it looked back at 12 highlights from the OHDSI community in 2021. If you aren’t receiving this newsletter each month, you can subscribe here. 

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Wednesday: REDHot OMOP: Facilitating Semantic Interoperability in REDCap with FHIR and the OMOP CDM
Thursday: Imputation of Continuous Measurements in Large Healthcare Databases: Comparing the Performance of Imputation Algorithms
Friday: An EUMAEUS investigation: how much can be gained in vaccine safety surveillance by including second dose data?

Patrick Ryan led the first OHDSI Community Call of 2022 with a presentation about what OHDSI can accomplish together this year. While the community listed and voted upon several objectives, Patrick discussed his hope to develop a system to generate evidence that characterizes disease and treatment utilization, estimates the effects of medical interventions, and predicts outcomes of patients within a network of observational health databases.

Other aspects of the discussion included a look at OHDSI workgroups and how they can continue moving forward, 2021 achievements, and more. Both video of the presentation and Patrick’s slides are available below.

Community Updates

• Congratulations to co-authors Nicolas Paris, Antoine Lamer and Adrien Parrot on the study “Transformation and Evaluation of the MIMIC Database in the OMOP Common Data Model: Development and Usability Study” which was published in JMIR Medical Informatics on Dec. 14.

• Congratulations to co-authors Sooin Choi, Soo Jeong Choi, Jin Kuk Kim, Ki Chang Nam, Suehyun Lee, Ju Han Kim and You Kyoung Lee on the study “Preliminary feasibility assessment of CDM-based active surveillance using current status of medical device data in medical records and OMOP-CDM” which was published in Scientific Reports on Dec. 15.

• Congratulations to co-authors Anastasiya Nestsiarovich, Jenna Reps, Michael Matheny, Scott DuVall, Kristine Lynch, Maura Beaton, Xinzhuo Jiang, Matthew Spotnitz, Stephen Pfohl, Nigam Shah, Carmen Olga Torre, Christian Reich, Dong Yun Lee, Sang Joon Son, Seng Chan You, Rae Woong Park, Patrick Ryan & Christophe Lambert on the study “Predictors of diagnostic transition from major depressive disorder to bipolar disorder: a retrospective observational network study” which was published in Translational Psychiatry on Dec. 20.

• Congratulations to co-authors Carlen Reyes, Andrea Pistillo, Sergio Fernández-Bertolín, Martina Recalde, Elena Roel, Diana Puente, Anthony Sena, Clair Blacketer, Lana Lai, Thamir Alshammari, Waheed-UI-Rahman Ahmed, Osaid Alser, Heba Alghoul, Carlos Areia, Dalia Dawoud, Albert Prats-Uribe, Neus Valveny, Gabriel de Maeztu, Luisa Sorlí Redó, Jordi Martinez Roldan, Inmaculada Lopez Montesinos, Lisa M Schilling, Asieh Golozar, Christian Reich, Jose Posada, Nigam Shah, Seng Chan You, Kristine Lynch, Scott DuVall, Michael Matheny, Fredrik Nyberg, Anna Ostropolets, George Hripcsak, Peter Rijnbeek, Marc Suchard, Patrick Ryan, Kristin Kostka, and Talita Duarte-Salles on the study “Characteristics and outcomes of patients with COVID-19 with and without prevalent hypertension: a multinational cohort study” which was published in BMJ Open on Dec. 22.

• Congratulations to co-authors Jenna Reps, Patrick Ryan, and Peter Rijnbeek on the study “Investigating the impact of development and internal validation design when training prognostic models using a retrospective cohort in big US observational healthcare data” which was published in BMJ Open on Dec. 24.

• The 2022 OHDSI European Symposium, which will be held at the Steam Ship Rotterdam in The Netherlands, has been moved to the new date of June 24-26. The main symposium will be June 24, and tutorials will be held June 25-26. For more information and the registration link, please visit the symposium homepage.

• The latest edition of “The Journey” OHDSI newsletter is now available, and it looked back at 12 highlights from the OHDSI community in 2021. If you aren’t receiving this newsletter each month, you can subscribe here.

• The #OHDSISocialShowcase continues this week, as we highlight all the global research presented at the OHDSI Symposium. Here is a look at the research being shared this week on Twitter and LinkedIn; please check them out and share with your own networks!

Monday: CohortIncidence: A Standardized Framework for Characterizing Incidence Using OMOP Common Data Model and OHDSI tools
Tuesday: Beyond Clinical: Integrating Research Assay Data into the Observational Health Data Sciences and Informatics Common Data Model (OHDSI CDM) through the Surgical Critical Care Initiative (SC2i)
Wednesday: Comparing Data Quality Dashboard results from consecutive ETL iterations: three new utilities
Thursday: Empirical Assessment of Alternative Methods for Identifying Seasonality in Observational Healthcare Data
Friday: ATLAS with a BigQuery backend running Execution Engine – a Software demo

OPENINGS

• Janssen R&D recently posted an “Associate Director, Observational Health Data Analytics” position in its world-class epidemiology department.

• The Bouvé College of Health Sciences and The Roux Institute at Northeastern University seek candidates for two full-time tenure-track Assistant Professor positions in the emerging area of health/healthcare data science. The successful candidate will have primary responsibility for working with the OHDSI Center at the Roux Institute, focusing on education, research and community support of the global Open Source OHDSI initiative. For more information, please reach out to Brianne Olivieri-Mui, Assistant Professor, Department of Health Sciences, at B.mui@northeastern.edu. 

Slides

Main Presentation (Ryan) | Community Updates

Video