The Winter 2025 vocabulary refresh was released last week and includes several domain changes, newly added concepts, concept changes and more. Please join our March 4 community call (11 am ET) for a full update on this recent refresh, led by

• Anna Ostropolets, Associate Director, Johnson & Johnson Innovative Medicine; Adjunct Assistant Professor, Columbia University
• Oleg Zhuk, Manager, Data Analytics Consulting, EPAM Systems
• Vlad Korsik, Vocabulary Technical Lead, EPAM Systems
• Masha Khitrun, Senior Scientific Curation Specialist, EPAM Systems

This session also included a Phenotype Phebruary review from two members of our leadership team: Anna Ostropolets and Azza Shoaibi.

Community Updates

• Congratulations to the team of Inessa Cohen, Zihan Diao, Pawan Goyal, Aarti Gupta, Kathryn Hawk, Bill Malcom, Caitlin Malicki, Dhruv Sharma, Brian Sweeney, Scott Weiner, Arjun Venkatesh, and Andrew Taylor on the recent publication of Mapping Emergency Medicine Data to the Observational Medical Outcomes Partnership Common Data Model: A Gap Analysis of the American College of Emergency Physicians Clinical Emergency Data Registry in the Journal of the American College of Emergency Physicians Open.

• Congratulations to the team of Seonji Kim, Subin Kim, Chungsoo Kim, Junhyuk Chang, Rae Woong Park, Kyung Won Kim, and Seng Chan You on the publication of Utility of Treatment Pattern Analysis Using a Common Data Model: A Scoping Review in Healthcare Informatics Research.

• The latest edition of The Journey Newsletter is now available, and it includes reviews of Phenotype Phebruary and workgroup updates, recent community updates, publications and presentations from February, and plenty more.

• Christian Reich and Sarah Seager are leading an effort to publish a second edition of the Book of OHDSI, which will include updates to previous text and new paragraphs/chapters. This work is taking place within the Education workgroup; if you would like to join this effort, please sign up here.

• Asieh Golozar announced that the iCAN mNSCLC Studyathon 2025 will be held March 25-28 I Helsinki, Finlad, and the focus is “Exploring the Real-World Treatment Landscape of mNSCLC.” The event will focus on characterizing real-world treatment patterns of metastatic NSCLC, with a focus on the adoption and impact of immune checkpoint inhibitors (ICIs) across different regions. Reach out to Asieh Golozar (golozar@ohdsi.org) for more information or if you wish to contribute.

• Please consider joining the Scientific Review Committee for the 2025 OHDSI Global Symposium, which will be held Oct. 7-9. Please fill out this form by March 4 if you are interested or want to learn more.

• Hongfang Liu will lead a talk on ‘A Translational Science Framework in Advancing Healthcare AI’ on March 27 at 11 am ET as part of The Center for Advanced Healthcare Research Informatics (CAHRI) at Tufts Medicine seminar series. Please contact Marty Alvarez at malvarez2@tuftsmedicalcenter.org for calendar invite or questions.

• Leaders from over 30+ workgroups presented opportunities for all community members to find a home for their talents and passions. Newcomers and veterans can both make meaningful contributions to our community by collaborating in workgroups. Throughout February, workgroup representatives shared the mission, recent achievements and 2025 goals. You can find those presentations and see if there is a home for you on our workgroups homepage.

Save The Dates

• The OHDSI Global Symposium will be held Oct. 7-9 at the Hyatt Regency Hotel in New Brunswick, NJ, USA. Agenda and registration information will be shared when available.

• The OHDSI Europe Symposium will be hosted by the OHDSI Belgium Node on 5-7 July 2025 in the “Old Prison” building of Hasselt University in Hasselt, Belgium. Agenda and registration information will be shared when available.

OHDSI Social Showcase

• Research from the 2024 Global Symposium Collaborator Showcase is also being shared daily on OHDSI’s LinkedIn, Twitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — Inclusion of intraocular pressure data into the University of California Health Data Warehouse (William Halfpenny and Shahin Hallaj)
Tuesday — Hierarchical Algorithms for Querying Physiologically Distinct Groups in Adult Congenital Heart Disease Using OMOP CDM (Seohu Lee)
Wednesday — Vasculitis without phlebitis phenotype development using real-world data: development and evaluation study (Jill Hardin)
Thursday — Using OHDSI Standards and Tools to Train the Next Generation of Researchers (Jonah Bradenday)
Friday — Comparing probabilistic and rule-based phenotype algorithms for hypotension and angioedema to the experience observed in randomized clinical trials (Joel Swerdel)

Job Postings

• Monica Gerber shared a job opening for an Analytics Engineer at Fred Hutchinson Cancer Research Center in Seattle, Washington. As an Analytics Engineer, you will collaborate with our data science team to design, build, and maintain multi-modal data models that integrate various data sources. Your work will support AI-driven research and translational data science use cases, helping to advance our scientific and technological goals. More information and an application link are available here.

Slides

Community Updates

Videos

Winter 2025 Vocabulary Refresh

Phenotype Phebruary Review 

Week 4 of Phenotype Phebruary is dedicated to iterating on cohort definitions & evaluating with additional OHDSI tools for the phenotypes that will be used in the guideline-driven evidence opportunities presented last month. Oleg Zhuk provided a tutorial on Cohort Diagnostics, while Anna Ostropolets and Azza Shoaibi discussed the progress of Phenotype Phebruary. 

OHDSI workgroups present opportunities for all community members to find a home for their talents and passions, and make meaningful contributions. Each year, workgroups discuss their mission, objectives and key results (OKRs) during February community calls. This video includes presentations by the Africa Chapter, Rare Diseases, Surgery & Perioperative Medicine, GIS, Natural Language Processing, Medical Devices, Oncology, Themis and CDM Survey workgroups.

Videos for both parts of the Feb. 25 community call are available below.

Community Updates

• Congratulations to the team of Jiyong An, Jiyun Kim, Leonard Sunwoo, Hyunyoung Baek, Sooyoung Yoo & Seunggeun Lee on the recent publication of De-identification of clinical notes with pseudo-labeling using regular expression rules and pre-trained BERT in BMC Medical Informatics and Decision Making.

• Congratulations to the team of Eun-Gee Park, Min Jung Kim, Jinseo Kim, Kichul Shin, and Borim Ryu on the publication of Utility of Treatment Pattern Analysis Using a Common Data Model: A Scoping Review in Healthcare Informatics Research.

• Congratulations to the team of Chen Yanover, Ramit Magen-Rimon, Erica A. Voss, Joel Swerdel, Anna Sheahan, Nathan Hall, Jimyung Park, Rae Woong Park, Kwang Jae Lee, Sung Jae Shin, Seung In Seo, Kyung-Joo Lee, Thomas Falconer, Leonard Haas, Paul Nagy, Mary Grace Bowring, Michael Cook, Steven Miller, Tal El-Hay, Maytal Bivas-Benita, Pinchas Akiva, Yehuda Chowers & Roni Weisshof on the recent publication of Characteristics and Outcomes of Over a Million Patients with Inflammatory Bowel Disease in Seven Countries: Multinational Cohort Study and Open Data Resource in Digestive Diseases and Sciences.

• Congratulations to the team of Cindy X. Cai Michelle Hribar, Sally Baxter, Kerry Goetz, Swarup S. Swaminathan, Alexis Flowers, Eric N. Brown, Brian Toy, Benjamin Xu, John Chen, Aiyin Chen, Sophia Wang, Cecilia Lee, Theodore Leng, Joshua R. Ehrlich, Andrew Barkmeier, Karen R. Armbrust, Michael V. Boland, David Dorr, Danielle Boyce, Thamir Alshammari, Joel Swerdel, Marc A. Suchard, Martijn Schuemie, Fan Bu, Anthony G. Sena, George Hripcsak, Akihiko Nishimura, Paul Nagy, Thomas Falconer, Scott L. DuVall, Michael Matheny, Benjamin Viernes, William O’Brien, Linying Zhang, Benjamin Martin, Erik Westlund, Nestoras Mathioudakis, Ruochong Fan, Adam Wilcox, Albert Lai, Jacqueline C. Stocking, Sahar Takkouche, Lok Hin Lee, Yangyiran Xie, Izabelle Humes, David B. McCoy, Mohammad Adibuzzaman, Raymond G. Areaux Jr, William Rojas-Carabali, James Brash, David A. Lee, Nicole G. Weiskopf, Louise Mawn, Rupesh Agrawal, Hannah Morgan-Cooper, Priya Desai, and Patrick B. Ryan on the recent publication of Semaglutide and Nonarteritic Anterior Ischemic Optic Neuropathy in JAMA Ophthalmology.

• Congratulations to the team of ChulHyoung Park, So Hee Lee, Da Yun Lee, Seoyoon Choi, Seng Chan You, Ja Young Jeon, Sang Jun Park, and Rae Woong Park on the publication of Analysis of Retinal Thickness in Patients With Chronic Diseases Using Standardized Optical Coherence Tomography Data: Database Study Based on the Radiology Common Data Model in JMIR Medical Informatics.

• Asieh Golozar announced that the iCAN mNSCLC Studyathon 2025 will be held March 25-28 I Helsinki, Finlad, and the focus is “Exploring the Real-World Treatment Landscape of mNSCLC​.” The event will focus on characterizing real-world treatment patterns of metastatic NSCLC, with a focus on the adoption and impact of immune checkpoint inhibitors (ICIs) across different regions. Reach out to Asieh Golozar (golozar@ohdsi.org) for more information or if you wish to contribute.

• Please consider joining the Scientific Review Committee for the 2025 OHDSI Global Symposium, which will be held Oct. 7-9. Please fill out this form by March 3 if you are interested or want to learn more.

Save The Dates

• The OHDSI Global Symposium will be held Oct. 7-9 at the Hyatt Regency Hotel in New Brunswick, NJ, USA. Agenda and registration information will be shared when available.

• The OHDSI Europe Symposium will be hosted by the OHDSI Belgium Node on 5-7 July 2025 in the “Old Prison” building of Hasselt University in Hasselt, Belgium. Agenda and registration information will be shared when available.

OHDSI Social Showcase

• Research from the 2024 Global Symposium Collaborator Showcase is also being shared daily on OHDSI’s LinkedIn, Twitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — Standardizing Rare Disease Patient Registry data to the OMOP-CDM (Parag Shiralkar)
Tuesday — Who Wants To Be A 2Billionaire? – A methodology for migrating from STCM to C/CR (Roger Carlson)
Wednesday — Leveraging the active comparator new user design to identify potential unknown benefits of canagliflozin (Justin Bohn)
Thursday — Does the SARS-CoV-2 Infection Increase the Onset of New Mental Health Disorder? Findings from Difference-in-Differences Analyses Using an EHR-Based Cohort from the RECOVER Program (Yiwen Lu)
Friday — dbt for OMOP Phase I: dbt-synthea (Katy Sadowski)

Job Postings

• Monica Gerber shared a job opening for an Analytics Engineer at Fred Hutchinson Cancer Research Center in Seattle, Washington. As an Analytics Engineer, you will collaborate with our data science team to design, build, and maintain multi-modal data models that integrate various data sources. Your work will support AI-driven research and translational data science use cases, helping to advance our scientific and technological goals. More information and an application link are available here.

Slides

Workgroup OKRs | Community Updates

Videos

Phenotype Phebruary, Week 4

Workgroup OKRs, Week 4

Week 3 of Phenotype Phebruary is dedicated to evaluating cohorts using CohortDiagnostics for the phenotypes that will be used in the guideline-driven evidence opportunities presented last month, and our leads will discuss next steps in this process.

OHDSI workgroups present opportunities for all community members to find a home for their talents and passions, and make meaningful contributions. Each year, workgroups discuss their mission, objectives and key results (OKRs) during February community calls. This video includes presentations by the OHDSI APAC, Generative AI and Foundational Models in Healthcare (GenAI), HADES, Eye Care and Vision Research, Latin America, Transplant, Databricks, Medical Imaging, and Psychiatry workgroups.

Videos for both parts of the Feb. 18 community call are available below.

Community Updates

• Congratulations to the team of Alicia Abellan, Edward Burn, Nhung T. H. Trinh, Theresa Burkard, Alison Callahan, Sergio Fernández-Bertolín, Eimir Hurley, Clara Rodriguez, Elena Segundo, Daniel R. Morales, Hedvig M. E. Nordeng, and Talita Duarte-Salles on the recent publication of Expanding the OMOP Common Data Model to Support Perinatal Research in Network Studies in Pharmacoepidemiology & Drug Safety.

• Congratulations to the team of Aurora Quaye, John DiPalazzo, Kristin Kostka, Janelle Richard, Blaire Beers-Mulroy, Meredith Peck, Robert Krulee, and Yi Zhang on the publication of Harmonizing population health data into OMOP common data model: a demonstration using COVID-19 sero-surveillance data from Nairobi Urban Health and Demographic Surveillance System in Frontiers in Digital Health.

• Asieh Golozar announced that the iCAN mNSCLC Studyathon 2025 will be held March 25-28 I Helsinki, Finlad, and the focus is “Exploring the Real-World Treatment Landscape of mNSCLC​.” The event will focus on characterizing real-world treatment patterns of metastatic NSCLC, with a focus on the adoption and impact of immune checkpoint inhibitors (ICIs) across different regions. Reach out to Asieh Golozar (golozar@ohdsi.org) for more information or if you wish to contribute.

• Phenotype Phebruary continues this week, with a focus on evaluating cohorts using CohortDiagnostics for the phenotypes that will be used in the guideline-driven evidence opportunities presented last month. You can follow everything going on in Phenotype Phebruary and contribute wherever you can.

• The goal of the OHDSI Rare Disease Working Group is to advance the understanding and treatment of rare diseases by leveraging real-world data, uniting multidisciplinary experts, and developing innovative methodologies to improve patient outcomes and inform clinical decision-making. The workgroup has posted a brief interest survey to help shape a productive and collaborative community. Please fill out this survey by Tuesday, Feb. 18.

Save The Dates

• The OHDSI Global Symposium will be held Oct. 7-9 at the Hyatt Regency Hotel in New Brunswick, NJ, USA. Agenda and registration information will be shared when available.

• The OHDSI Europe Symposium will be hosted by the OHDSI Belgium Node on 5-7 July 2025 in the “Old Prison” building of Hasselt University in Hasselt, Belgium. Agenda and registration information will be shared when available.

OHDSI Social Showcase

• Research from the 2024 Global Symposium Collaborator Showcase is also being shared daily on OHDSI’s LinkedIn, Twitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — Going global, redeeming the local: an innovative approach to implement the OMOP CDM in two countries of the Global South (Valentina Martufi)
Tuesday — A Computable Phenotype for HSV Anterior Uveitis: Operationalizing the SUN Classification Criteria (Brian Toy)
Wednesday — Comparative Evaluation of Methods for Defining Observation Periods in Healthcare Databases and Their Impact on Incidence Rate Estimates (Clair Blacketer)
Thursday — How Often: Large Scale Incidence Rate Calculation of Health Outcomes for Drugs Nested by Indication (Hsin Yi Chen)
Friday — FinOMOP Swarm Learning – Deep learning for patient-specific modelling of Acute Myeloid Leukemia (Salma Rachidi)

Job Postings

• Monica Gerber shared a job opening for an Analytics Engineer at Fred Hutchinson Cancer Research Center in Seattle, Washington. As an Analytics Engineer, you will collaborate with our data science team to design, build, and maintain multi-modal data models that integrate various data sources. Your work will support AI-driven research and translational data science use cases, helping to advance our scientific and technological goals. More information and an application link are available here.

Slides

Phenotype Phebruary |  Workgroup OKRs | Community Updates

Videos

Phenotype Phebruary, Week 3

Workgroup OKRs, Week 3

Week 2 of Phenotype Phebruary is dedicated to developing concept sets and constructing logical frameworks for the phenotypes that will be used in the guideline-driven evidence opportunities presented last month, and our leads will discuss next steps in this process. 

OHDSI workgroups present opportunities for all community members to find a home for their talents and passions, and make meaningful contributions. Each year, workgroups discuss their mission, objectives and key results (OKRs) during February community calls. This video includes presentations by the Methods Research, Common Data Model, Evidence Network, Patient-Level Prediction (PLP), Early-Stage Researchers, Women of OHDSI, and ATLAS workgroups.

Videos for both parts of the Feb. 11 community call are available below.

Community Updates

• Congratulations to the team of Justin Quon, Christopher Long, William Halfpenny, Amy Chuang, Cindy Cai, Sally Baxter, Vamsi Daketi, Amanda Schmitz, Neil Bahroos, Benjamin Xu, and Brian Toy on the recent publication of Implementing a Common Data Model in Ophthalmology: Mapping Structured Electronic Health Record Ophthalmic Examination Data to Standard Vocabularies in Ophthalmology Science.

• Congratulations to the team of Aurora Quaye, John DiPalazzo, Kristin Kostka, Janelle Richard, Blaire Beers-Mulroy, Meredith Peck, Robert Krulee, and Yi Zhang on the publication of Identifying factors associated with persistent opioid use after total joint arthroplasty: a retrospective review in Pain Medicine.

• Congratulations to the team of Kevin Ouazzani, Xavier Ansolabehere, Florence Journeau, Alexandre Vidal, Nicolas Jaubourg, Maxime Doublet, Raphael Thollot, Arnaud Fabre, and Nicolas Glatt on the recent publication of Project Victoria: A pragmatic data model to automate RWE generation from the national French claims database in the Health Informatics Journal.

• Fourteen OHDSI collaborators provided presentations about guideline-driven evidence opportunities for community network studies. You can see those talks here, and share what studies you would like to join.

• The goal of the OHDSI Rare Disease Working Group is to advance the understanding and treatment of rare diseases by leveraging real-world data, uniting multidisciplinary experts, and developing innovative methodologies to improve patient outcomes and inform clinical decision-making. The workgroup has posted a brief interest survey to help shape a productive and collaborative community. Please fill out this survey by Tuesday, Feb. 18.

Save The Dates

• The OHDSI Global Symposium will be held Oct. 7-9 at the Hyatt Regency Hotel in New Brunswick, NJ, USA. Agenda and registration information will be shared when available.

• The OHDSI Europe Symposium will be hosted by the OHDSI Belgium Node on 5-7 July 2025 in the “Old Prison” building of Hasselt University in Hasselt, Belgium. Agenda and registration information will be shared when available.

OHDSI Social Showcase

• Research from the 2024 Global Symposium Collaborator Showcase is also being shared daily on OHDSI’s LinkedIn, Twitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — Evaluating the impact of different vocabulary versions on cohort definitions and CDM (Dmitry Dymshyts)
Tuesday — The state of federated health data networks globally in 2024 (Michael Briganti)
Wednesday — Comparison of Deep Learning and Conventional Strategies for Disease Onset Prediction: An OHDSI Network Study (Henrik John)
Thursday — Prediction of Severe Respiratory Infections in Patients with Diabetes (Nguyen Thi Kim Hien)
Friday — Visualising OMOP concept relationships with omopcept (Andy South)

Job Postings

• Monica Gerber shared a job opening for an Analytics Engineer at Fred Hutchinson Cancer Research Center in Seattle, Washington. As an Analytics Engineer, you will collaborate with our data science team to design, build, and maintain multi-modal data models that integrate various data sources. Your work will support AI-driven research and translational data science use cases, helping to advance our scientific and technological goals. More information and an application link are available here.

Slides

Phenotype Phebruary |  Workgroup OKRs | Community Updates

Videos

Phenotype Phebruary, Week 2 (tutorial breakouts below)

Workgroup OKRs, Week 2

Tutorial: Concept Set Creation (Tatiana Skugarevskaya)

Tutorial: Cohort Definition Creation (Kevin Haynes)

Welcome to Phenotype Phebruary 2025! Now in its fourth year, Phenotype Phebruary focuses on building upon the guideline-driven evidence opportunities presented last month, and the first week will focus on creating clinical descriptions for cohorts that may be used in these studies. This community call highlighted how and where this work can be done, and why it will provide the foundation for future work done in these network studies. You can follow updates on Phenotype Phebruary on this forum thread, and you can share your interest in joining the collaboration via this form.

OHDSI workgroups present opportunities for all community members to find a home for their talents and passions, and make meaningful contributions. Each year, workgroups discuss their mission, objectives and key results (OKRs) during February community calls. This session included presentations by the Health Systems Interest Group, Vocabulary, Rehabilitation, Perinatal and Reproductive Health, and the Steering Group. 

Videos for both presentations are available below.

Community Updates

• Congratulations to the team of Gyubeom Hwang, So Hee Lee, Dong Yun Lee, ChulHyoung Park, Hyun Woong Roh, Sang Joon Son, and Rae Woong Park on the recent publication of Age-related eye diseases and subsequent risk of mental disorders in older adults: A real-world multicenter study in the Journal of Affective Disorders.

• Congratulations to the team of Noah Jones, Ming-Chieh Shih, Elizabeth Healey, Chen Wen Zhai, Sonali Advani, Aaron Smith-McLallen, David Sontag, and Sanjat Kanjilal on the publication of Use of Machine Learning to Assess the Management of Uncomplicated Urinary Tract Infection in JAMA Network Open.

• Congratulations to the team of Seok Jun Park, Seungwon Yang, Suhyun Lee, Sung Hwan Joo, Taemin Park, Dong Hyun Kim, Hyeonji Kim, Soyun Park, Jung-Tae Kim, Won Gun Kwack, Sung Wook Kang, Yun-Kyoung Song, Jae Myung Cha, Sang Youl Rhee, and Eun Kyoung Chung on the recent publication of Machine-Learning Parsimonious Prediction Model for Diagnostic Screening of Severe Hematological Adverse Events in Cancer Patients Treated with PD-1/PD-L1 Inhibitors: Retrospective Observational Study by Using the Common Data Model in Diagnostics.

• Fourteen OHDSI collaborators provided presentations about guideline-driven evidence opportunities for community network studies. You can see those talks here, and share what studies you would like to join.

• The goal of the OHDSI Rare Disease Working Group is to advance the understanding and treatment of rare diseases by leveraging real-world data, uniting multidisciplinary experts, and developing innovative methodologies to improve patient outcomes and inform clinical decision-making. The workgroup has posted a brief interest survey to help shape a productive and collaborative community. Please fill out this survey by Tuesday, Feb. 18.

• The latest OHDSI newsletter is now available. It includes information about the 14 guideline-driven evidence opportunities presented in January, the monthly podcast, community updates, the latest collaborator spotlight, recent publications and presentations, and plenty more. If you don’t receive the newsletter each month, you can subscribe here.

• Dr. Cynthia Sung is an Adjunct Associate Professor for the Centre of Regulatory Excellence at Duke-National University of Singapore Medical School, teaching and developing curricula for the Graduate Certificate in Health Products Regulation. She is an active member of the OHDSI Community, primarily as co-lead for the OHDSI Africa Chapter and also participating in working groups for Clinical Trials and Pregnancy and Reproductive Health. She was honored with the 2023 Titan Award for Community Collaboration. In the latest collaborator spotlight, Cynthia discusses a career journey that has taken her around the world, the need for FAIR data in less-represented populations, exciting developments within Africa, and more.

Save The Dates

• The OHDSI Global Symposium will be held Oct. 7-9 at the Hyatt Regency Hotel in New Brunswick, NJ, USA. Agenda and registration information will be shared when available.

• The OHDSI Europe Symposium will be hosted by the OHDSI Belgium Node on 5-7 July 2025 in the “Old Prison” building of Hasselt University in Hasselt, Belgium. Agenda and registration information will be shared when available.

OHDSI Social Showcase

• Research from the 2024 Global Symposium Collaborator Showcase is also being shared daily on OHDSI’s LinkedIn, Twitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — SMEs optimization with high precision data ingestion of CAPriCORN CDM onto OMOP at AllianceChicago (Andrew Hamilton)
Tuesday — Automating data standardization through ad hoc SNOMED modeling with LLM: proof of concept (Eduard Korchmar)
Wednesday — Is the Observed Protection of COVID-19 Vaccines Against Infection within 14 days Real or an Artifact? A Negative Control Outcomes-Based Investigation Using Real-World Data (Bingyu Zhang)
Thursday — Risk of Dysmetabolic Syndrome in Post-Acute COVID-19 Among Children and Adolescents: An EHR Cohort Study from the RECOVER Initiative (Yuqing Lei)
Friday — Advancing the OHDSI Analysis Viewer: Enhanced Performance, Integration, and User Experience (Nathan Hall)

Job Postings

• Monica Gerber shared a job opening for an Analytics Engineer at Fred Hutchinson Cancer Research Center in Seattle, Washington. As an Analytics Engineer, you will collaborate with our data science team to design, build, and maintain multi-modal data models that integrate various data sources. Your work will support AI-driven research and translational data science use cases, helping to advance our scientific and technological goals. More information and an application link are available here.

Slides

Phenotype Phebruary | Workgroup OKRs | Community Updates

Videos

Phenotype Phebruary, Week 1

Workgroup OKRs, Week 1 

One proposed focus for the OHDSI community is around guideline-driven evidence generation, and collaborators have started to share potential opportunities in this forum post. We heard more the following guideline-focused opportunities during our Jan. 28 community call. 1) Antithrombotic use post-PCI (Chang Hoon Han & Seng Chan You) 
2) Bladder cancer treatment (Asieh Golozar)
3) Rheumatology DMARD infection management (Christopher Mecoli)
4) Anesthesia post-operative care (Oleg Zhuk)
5) Schizophrenia pharmacotherapy (Tatiana Skugarevskaya)
6) Post-herpetic neuralgia management (Masha Khitrun)
7) TPO-RA to manage cytopenias in solid tumors (Vlad Korsik)
8) Diabetic retinopathy screening (Cindy Cai)
9) Osteoporosis management (Chen Yanover and Vanessa Rouach)
10) Melanoma PD-1/PD-L1 inhibitor therapy (Bohdan Khilchevskyi)
11) Pediatric vision screening (Michelle Hribar)

Please use this form to share which guideline-driven evidence opportunities you would like to contribute to, and how you plan to contribute to the evidence generation process.

Community Updates

• Congratulations to the team of Seok Jun Park, Seungwon Yang, Suhyun Lee, Sung Hwan Joo, Taemin Park, Dong Hyun Kim, Hyeonji Kim, Soyun Park, Jung-Tae Kim, Won Gun Kwack, Sung Wook Kang, Yun-Kyoung Song, Jae Myung Cha, Sang Youl Rhee, and Eun Kyoung Chung on the recent publication of Machine-Learning Parsimonious Prediction Model for Diagnostic Screening of Severe Hematological Adverse Events in Cancer Patients Treated with PD-1/PD-L1 Inhibitors: Retrospective Observational Study by Using the Common Data Model in Diagnostics.

• Each year, workgroup representatives join a February community call to present the mission, objectives and key results for their respective groups. These 2-4 minute presentations are recorded and posted on the Workgroups homepage on OHDSI.org. Please choose a date to sign up for a February date; once a date has at least 10 workgroups, it will be closed.

Save The Dates

• The OHDSI Europe Symposium will be hosted by the OHDSI Belgium Node on 5-7 July 2025 in the “Old Prison” building of Hasselt University in Hasselt, Belgium. Agenda and registration information will be shared when available.

OHDSI Social Showcase

• Research from the 2024 Global Symposium Collaborator Showcase is also being shared daily on OHDSI’s LinkedIn, Twitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — NCO-Calibrated DID Analysis: Addressing Unmeasured Confounding in Difference-in-Differences Analyses Using Negative Control Outcomes Experiments (Dazheng Zhang)
Tuesday — Improving Team Science Through “Thons” Reflections on the April Olympians Community Event (Clair Blacketer, Melanie Philofsky)
Wednesday — Clinically validated line of therapy (LoT) algorithm for patients with metastatic Non-Small Cell Lung Cancer (mNSCLC) can be implemented using systemic anti-cancer therapy (SACT) in Observational Medical Outcomes Partnership (OMOP) database (Joana Moreira)
Thursday — Impact of phenotype error adjustment on background incidence of COVID19 vaccine adverse events of special interest (James Weaver)
Friday — End-to-End Implementation of a Workflow for Validating Semantic Mappings and Constructing Ontology Extensions (Jared Houghtaling)

Slides

Community Updates

Videos

Clinical Guideline Review

One proposed focus for the OHDSI community is around guideline-driven evidence generation, and collaborators have started to share potential opportunities in this forum post. We heard more about some of these guideline-focused opportunities (obesity, pneumonia, time varying treatment pathways) during our Jan. 21 community call, and we also learned about the BRIDGE Training Program from Marc Twagirumukiza. 

Community Updates

• Congratulations to the team of Mitchell Conover, Yasser Albogami, Jill Hardin, Christian Reich, Anna Ostropolets, Patrick Ryan, and the OHDSI Research Network on the recent publication of Glucagon-Like Peptide 1 Receptor Agonists and Chronic Lower Respiratory Disease Among Type 2 Diabetes Patients: Replication and Reliability Assessment Across a Research Network in Pharmacoepidemiology & Drug Safety.

• Congratulations to the team of Karamarie Fecho, Juan J. Garcia, Hong Yi, Griffin Roupe and Ashok Krishnamurthy on the recent publication of FHIR PIT: a geospatial and spatiotemporal data integration pipeline to support subject-level clinical research in BMC Medical Informatics and Decision Making.

• Congratulations to the team of Gowtham Rao, Azza Shoaibi, Rupa Makadia, Jill Hardin, Joel Swerdel, James Weaver, Erica Voss, Mitchell Conover, Stephen Fortin, Anthony Sena, Chris Knoll, Nigel Hughes, James Gilbert, Clair Blacketer, Alan Andryc, Frank DeFalco, Anthony Molinaro, Jenna Reps, Martijn Schuemie, and Patrick Ryan on the recent publication of CohortDiagnostics: Phenotype evaluation across a network of observational data sources using population-level characterization in PLOS One.

• Each year, workgroup representatives join a February community call to present the mission, objectives and key results for their respective groups. These 2-4 minute presentations are recorded and posted on the Workgroups homepage on OHDSI.org. Please choose a date to sign up for a February date; once a date has at least 10 workgroups, it will be closed.

• The CDM Survey subgroup invites colleagues who have or are going to design, develop, and/or implement research surveys and use them with the OMOP CDM to share information about those efforts by completing this survey. Your completion of this 10-15 minute survey will provide information to the CDM workgroup about OMOP utilization among survey research teams.  The CDM Survey subgroup is a collaborative effort, led by a team at the National Cancer Institute, to develop standardized approaches and best practices for helping research teams better integrate survey data elements into the OMOP common data model. The survey will remain open through mid-January.

Save The Dates

• The OHDSI Europe Symposium will be hosted by the OHDSI Belgium Node on 5-7 July 2025 in the “Old Prison” building of Hasselt University in Hasselt, Belgium. Agenda and registration information will be shared when available.

OHDSI Social Showcase

• Research from the 2024 Global Symposium Collaborator Showcase is also being shared daily on OHDSI’s LinkedIn, Twitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — Leveraging UDI for Advanced Medical Device Tracking in OMOP-CDM (Seojeong Shin)
Tuesday — OMOP on a Data Lake: Addressing the Critical Need for Scalable Solutions in Healthcare Data Management with OHDSI Tools and AWS Services (Lance Eighme)
Wednesday — Generalizable Approaches for Medical Term Normalization (Jacob Berkowitz)
Thursday — Exploring the interplay between metabolic syndrome and brain volume in depression: Basis for Phenotype-Based Classification (Sujin Gan)
Friday — Quantifying the opioid use disorder crisis: PULSNAR finds nearly 3/4 undiagnosed (Praveen Kumar)

Slides

Bridge Training Program | Community Updates

Videos

Bridge Training Program (Marc Twagirumukiza) 

Clinical Guideline Review (Chungsoo Kim, Anna Ostropolets, Kevin Haynes)

We shared some potential focuses for 2025 during the Jan. 7 community call, and they each require collaboration within the community. During this call, we provided a forum to discuss opportunities, meet new potential collaborators and ideally build connections that can spark this work.

Community Updates

• Congratulations to the team of Melissa Finster, Maxim Moinat and Elham Taghizadeh on the recent publication of ETL: From the German Health Data Lab data formats to the OMOP Common Data Model in PLOS One.

• Congratulations to the team of Martijn Schuemie, Anna Ostropolets, Aleh Zhuk, Uladzislau Korsik, Seung In Seo, Marc Suchard, George Hripcsak and Patrick Ryan on the recent publication of Standardized patient profile review using large language models for case adjudication in observational research in NPJ Digital Medicine.

• Congratulations to the team of Noah Hong, Yeh-Hee Ko, Jeong Hyun Park, Eun Jin Ha, Sung Ho Lee, Kang Min Kim, Hyun-Seung Kang, Jeong Eun Kim, Kwangsoo Kim, and Won-Sang Cho on the recent publication of A common data model for oral anticoagulants-related risk of spontaneous intracranial hemorrhage in the Journal of Clinical Neuroscience.

• Congratulations to the team of Young-Eun Kwon, Shin-Young Ahn, Gang-Jee Ko, Young-Joo Kwon and Ji-Eun Kim on the recent publication of Impact of Uric Acid Levels on Mortality and Cardiovascular Outcomes in Relation to Kidney Function in the Journal of Clinical Medicine.

• Congratulations to the team of Mitchell Conover, Patrick Ryan, Yong Chen, Marc Suchard, George Hripcsak, and Martijn Schuemie on the recent publication of Objective study validity diagnostics: a framework requiring pre-specified, empirical verification to increase trust in the reliability of real-world evidence in JAMIA.

• Each year, workgroup representatives join a February community call to present the mission, objectives and key results for their respective groups. These 2-4 minute presentations are recorded and posted on the Workgroups homepage on OHDSI.org. Please choose a date to sign up for a February date; once a date has at least 10 workgroups, it will be closed.

• The next edition of the CBER BEST Seminar Series will be Jan. 15, 2025 at 11 am ET. We are happy to welcome Sonia Hernández-Díaz, MD, DrPH, Professor of Epidemiology, Harvard T.H. Chan School of Public Health, who will provide a talk on “Emulation of Target Trial on Vaccinations During Pregnancy.” More information and the meeting link are available on the CBER BEST series homepage.

• The CDM Survey subgroup invites colleagues who have or are going to design, develop, and/or implement research surveys and use them with the OMOP CDM to share information about those efforts by completing this survey. Your completion of this 10-15 minute survey will provide information to the CDM workgroup about OMOP utilization among survey research teams.  The CDM Survey subgroup is a collaborative effort, led by a team at the National Cancer Institute, to develop standardized approaches and best practices for helping research teams better integrate survey data elements into the OMOP common data model. The survey will remain open through mid-January.

• All videos and slides from the main conference of the 2024 OHDSI Global Symposium are now available on the event homepage. You can also find the 136 posters and software demos from our collaborator showcase. Videos of all the tutorials have also been posted.

Save The Dates

• The OHDSI Europe Symposium will be hosted by the OHDSI Belgium Node on 5-7 July 2025 in the “Old Prison” building of Hasselt University in Hasselt, Belgium. Agenda and registration information will be shared when available.

OHDSI Social Showcase

• Research from the 2024 Global Symposium Collaborator Showcase is also being shared daily on OHDSI’s LinkedIn, Twitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — Lessons from mapping cancer information from European hospitals to ICD-O-3 conditions in OMOP (Lars Halvorsen)
Tuesday — Jackalope Plus Performance: Benchmarking and Competitors (Denys Kaduk)
Wednesday — Trade-offs in the design of explainable prediction models for health care (Aniek Markus)
Thursday — An interactive approach for data exploration and phenotyping in the Data2Evidence platform (Satish Anbazhagan)
Friday — An Active Safety Surveillance Using Real-World Evidence (ASSURE) Approach to Pharmacovigilance Signal Evaluation: The case of infliximab and alternative autoimmune conditions (Kevin Haynes)

Slides

Where Can OHDSI Go In 2025? | Community Updates

Video

Breakouts were not recorded

OHDSI kicked off its 2025 community calls with a session focused on where we can go together over the next 12 months. Patrick Ryan highlighted four focus areas for the community: guideline-driven evidence generation, evidence-driven data standardization, evidence-driven open-source development, and evidence-driven collaborative education. There were details about monthly events, and upcoming clinical/scientific conferences over the next 18 months that can be end goals for dissemination. 

Community Updates

• Congratulations to the team of Shuxin Zhang, Ronald Cornet and Nirupama Benis on the recent publication of Cross-Standard Health Data Harmonization using Semantics of Data Elements in Scientific Data.

• Congratulations to the team of Tobias Freyberg Justesen, Adile Orhan, Andreas Weinberger Rosen, Mikail Gögenur, and Ismail Gögenur on the recent publication of Mismatch Repair Status and Surgical Outcomes in Localized Colorectal Cancer: A Nationwide Cohort Study in Annals of Surgery Open.

• Congratulations to the team of Rowdy de Groot, Frank van der Graaff, Daniël van der Doelen, Michiel Luijten, Ronald De Meyer, Hekmat Alrouh, Hedy van Oers, Jacintha Tieskens, Josjan Zijlmans, Meike Bartels, Arne Popma, Nicolette de Keizer, Ronald Cornet, and Tinca Polderman on the recent publication of Implementing Findable, Accessible, Interoperable, Reusable (FAIR) Principles in Child and Adolescent Mental Health Research: Mixed Methods Approach in JMIR Mental Health.

• Congratulations to the team of Chen Yanover, Ramit Magen-Rimon, Erica A. Voss, Joel Swerdel, Anna Sheahan, Nathan Hall, Jimyung Park, Rae Woong Park, Kwang Jae Lee, Sung Jae Shin, Seung In Seo, Kyung-Joo Lee, Thomas Falconer, Leonard Haas, Paul Nagy, Mary Grace Bowring, Michael Cook, Steven Miller, Tal El-Hay, Maytal Bivas-Benita, Pinchas Akiva, Yehuda Chowers and Roni Weisshof on the recent publication of Characteristics and Outcomes of Over a Million Patients with Inflammatory Bowel Disease in Seven Countries: Multinational Cohort Study and Open Data Resource in Digestive Diseases & Sciences.

• Congratulations to the team of Yu Jeong Lee, Jinmi Kim, Dong Han Yu, Nam Kyung Je and Harin Rhee on the recent publication of Long-term use of proton pump inhibitors was associated with rapid progression to end stage kidney disease in a Korean nationwide study in Scientific Reports.

 • Congratulations to the team of Harry-Anton Talvik, Marek Oja, Sirli Tamm, Kerli Mooses, Dage Särg, Marcus Lõo, Õie Renata Siimon, Hendrik Šuvalov, Raivo Kolde, Jaak Vilo, Sulev Reisberg, and Sven Laur on the recent publication of Repeatable process for extracting health data from HL7 CDA documents in the Journal of Biomedical Informatics.

• Congratulations to the team of Anna O. Basile, Anurag Verma, Leigh Anne Tang, Marina Serper, Andrew Scanga, Ava Farrell, Brittney Destin, Rotonya M. Carr, Anuli Anyanwu-Ofili, Gunaretnam Rajagopal, Abraham Krikhely, Marc Bessler, Muredach P. Reilly, Marylyn D. Ritchie, Nicholas P. Tatonetti, and Julia Wattacheril on the recent publication of Rapid identification and phenotyping of nonalcoholic fatty liver disease patients using a machine-based approach in diverse healthcare systems in Clinical and Translational Science.

• Congratulations to the team of Rowdy de Groot, Savannah Glaser, Alexandra Kogan, Stephanie Medlock, Anna Alloni, Matteo Gabetta, Szymon Wilk, Nicolette de Keizer, and Ronald Cornet on the recent publication of ATC-to-RxNorm mappings – A comparison between OHDSI Standardized Vocabularies and UMLS Metathesaurus in the International Journal of Medical Informatics.

• Save The Date! The OHDSI Europe Symposium will be hosted by the OHDSI Belgium Node on 5-7 July 2025 in the “Old Prison” building of Hasselt University in Hasselt, Belgium. Agenda and registration information will be shared when available.

• Each year, workgroup representatives join a February community call to present the mission, objectives and key results for their respective groups. These 2-4 minute presentations are recorded and posted on the Workgroups homepage on OHDSI.org. Please choose a date to sign up for a February date; once a date has at least 10 workgroups, it will be closed.

• The next edition of the CBER BEST Seminar Series will be Jan. 15, 2025 at 11 am ET. We are happy to welcome Sonia Hernández-Díaz, MD, DrPH, Professor of Epidemiology, Harvard T.H. Chan School of Public Health, who will provide a talk on “Emulation of Target Trial on Vaccinations During Pregnancy.” More information and the meeting link are available on the CBER BEST series homepage.

• The latest edition of The Journey Newsletter is now available. The latest edition reflects back on 2024, highlights 10 recent published studies, and includes community updates, the latest collaborator spotlight, OHDSI presentations, and more.

• The CDM Survey subgroup invites colleagues who have or are going to design, develop, and/or implement research surveys and use them with the OMOP CDM to share information about those efforts by completing this survey. Your completion of this 10-15 minute survey will provide information to the CDM workgroup about OMOP utilization among survey research teams.  The CDM Survey subgroup is a collaborative effort, led by a team at the National Cancer Institute, to develop standardized approaches and best practices for helping research teams better integrate survey data elements into the OMOP common data model. The survey will remain open through mid-January.

• All videos and slides from the main conference of the 2024 OHDSI Global Symposium are now available on the event homepage. You can also find the 136 posters and software demos from our collaborator showcase. Videos of all the tutorials have also been posted.

OHDSI Social Showcase

• Research from the 2024 Global Symposium Collaborator Showcase is also being shared daily on OHDSI’s LinkedIn, Twitter/X and Instagram feeds as part of the #OHDSISocialShowcase. Below are posters (with study leads) that are featured this week:

Monday — Institutionalizing data interoperability and the application of common data models in a health data and research center: CIDACS’ experience in Brazil (Valentina Martufi)
Tuesday —Characterizing Phenotype Descriptions in All of Us Publications (Emily Clark)
Wednesday — Fine-Tuning Foundational AI Models to Code Diagnoses from Veterinary Health Records (Mayla R. Boguslav)
Thursday — Brain-penetrant calcium channel blockers for psychiatric use: revisiting the evidence for benefit (David Kern)
Friday —CohortOperations: A Modular Web Tool for Enhanced Cohort Analysis on the OMOP-CDM (Javier Gracia-Tabuenca)

Slides

Where Can OHDSI Go In 2025? | Community Updates

Video