In this workshop, the ‘OHDSI reproducibility challenge’ will aim to reproduce the populations (exposures and outcomes) used in an analysis by Albogami et al (see workshop homepage for more details). We will also aim to quantify the heterogeneity of interpretations that qualified researchers may produce when attempting to reproduce the same study. The OHDSI reproducibility challenge is being conducted in collaboration with the lead author of the original study, though for the purposes of the workshop, only the information in the publication and supplemental materials will be used.
Teams will independently work on two study design tasks, to be implemented in OHDSI ATLAS: 1) define the target exposure cohort, and 2) create cohorts for the primary and secondary outcomes. All teams will be provided access to an ATLAS instance with an empty cohort definition template, pre-populated with the necessary conceptsets to produce the cohorts, such that the focus of the reproducibility is