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Extend OMOP CDM and Vocabulary and OHDSI analytic platform to support transfusion research
Transfusions are special treatments which are currently in active research by the FDA BEST and the REDS-IV program. The current OMOP CDM allows only partial capture of relevant transfusion information to support the various research use cases (see below). This Working Group intends to close that gap.
* Use Cases:
* Effect of number of units on outcomes * Effect of single donor vs pooled on outcomes * Effect agency blood products are obtained from (such as ARC vs NYBC) on outcomes * Incidence rates of severe outcomes: TRALI, TACO, Sepsis, HTRs, PTP, thrombosis and others * Fatality rates of outcomes * Incidence rates of outcomes by specific blood products transfused: red blood cells, plasma, platelets, full blood * Incidence rates of outcomes by blood component processing: leukocyte reduction, irradiation, pathogen-reduction * Incidence rates of outcomes by indication and associated procedures and other possible risk factors * Incidence rates of outcomes by donor characteristics
* Modelling Isues:
* Detailed facts about transfused units, such as