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Objective: The objective of this workgroup (WG) is to establish an open-source standardized knowledge base for the effects of medical products and an efficient procedure for maintaining and expanding it. For a complete overview, please see the paper Bridging islands of information to establish an integrated knowledge base of drugs and health outcomes of interest. The WG's first contribution to OHDSI will be LAERTES (Largescale Adverse Effects Related to Treatment Evidence Standardization) – a system that integrates numerous sources of evidence useful for investigating the association of drugs and health into a single system. The system will extend the OHDSI Standard Vocabulary and provide for summary and drill down evidence review use cases. The first release of LAERTES is schedule for April 2015
Project Lead: Richard D. Boyce, PhD
Project Co-Lead: Patrick Ryan, PhD
Members:
See Members List
Start Date: 6/10/2014
Repository: https://github.com/OHDSI/KnowledgeBase
WG Minutes: Knowledge Base WG Minutes
WG Agendas: Knowledge Base WG Agendas
Schedule: Every other Wednesday at 12 Eastern starting from January 14th 2015 Please join my meeting. https://global.gotomeeting.com/join/530277469
You can call in for audio: Dial +1 (646) 749-3122 Access Code: 530-277-469
update of the pharmacovigilance signals
LAERTES: pre-load queries - hoi from X to snomed, rxnorm BD to CD
LAERTES: getting the pivot correct - ‘rolling up’ from clinical drug to ingredient
- Abraham G. Hartzema, PhD, University of Florida, Gainesville, FL
- Christian Reich, MD, PhD, AstraZeneca, Waltham MA
- Christophe Lambert, PhD, University of New Mexico, Albuquerque, NM
- Erica A. Voss, MPH, Janssen Research and Development, Titusville, PA
- Gianluca Trifirò, PhD, University of Messina, Messina, Italy & Erasmus University Medical Center, Rotterdam, Netherlands
- J. Marc Overhage, MD, PhD, Siemens Healthcare, Malvern, PA
- Jon Duke, MD, Regenstrief Institute, Indianapolis IN
- Johan Ellenius, PhD, Uppsala Monitoring Centre, Uppsala, Sweden
- Lee Evans, LTS Computing LLC, West Chester, PA
- Majid Rastegar-Mojarad, MS, Mayo Clinic, Rochester, MN
- Mark Khayter, BS, Ephir, Boston, MA
- Martijn J. Schuemie, PhD, Janssen Research and Development, Titusville, PA
- Michel Dumontier, PhD, Stanford University, Stanford, CA
- Nicholas P. Tatonetti, PhD, Columbia University, New York, NY
- Niklas Noren, PhD, Uppsala Monitoring Centre, Uppsala, Sweden
- Rave Harpaz, PhD, Stanford University, Palo Alto, CA
- Vojtech Huser, MD PhD, National Institutes of Health, Bethesda, MD