Should certainty be merged with negation? - in instances where the negation is not about certainty (existential/systemic), it would be better to keep them separate. Another point to think about is the utility of the categories (definite, probable, uncertain, probable negated, definite negated) and the ability of NLP systems to annotate the terms with them. Boolean negation is easier to annotate and handle.
Granularity of modifiers for subject - Family, Other, Patient may be sufficient for current datasets
Generic/conditional modifier - Generic and Conditional as modifier may be acceptable. cTAKES does not support this currently.
Course - possible values (very limited set) presented. Same as cTAKES. Default way of dealing with it could be to assign the ontology and the value from it. Open ended for now. Can be modified later based on use cases/usage.
Temporal - is pulled from cTAKES, could be improved.
Discovery technique - Name of NLPtool, in cTAKES currently, the methodology (gold-standard, rule-based, dictionary look-up etc.) used is the discovery technique. Utility? - needs to be discussed
Confidence score - how reliable
Disease specific modifiers - Body location, Severity (some values overlap with cTAKES)
Medication specific modifiers - need to maybe add strength?
Test specific - Change reference range to lower threshold, upper threshold?
Procedure specific modifiers - need examples before discussion, body location, also add laterality here.