**The group agreed to explore the onco domains in the following order:**
 
  - Diagnosis
  - Treatment
  - Outcomes survival
  - Molecular biomarkers
  - Pathology reports
  - Imaging
  - Performance status

**Existing standards**
 
·         Tumor Registry, CDISC and SEER are the existing standards and efforts in harmonizing the data collection.
 
**Exploratory data set**

·         Christian would try putting together a working data set

**ICD-O-3 overview**

[[https://drive.google.com/file/d/0Bzcc8twUxevJcVpybm8zX2dUZWs/view?usp=sharing.| Michael Gurley's ICD-O-3 Presentation and proposal for CDM cancer diagnosis modeling ]]

  * ICD-O-3 provides most granular representation of cancer diagnosis including anatomic side and morphological/behavior.
  * Diagnosis can be represented in condition_occurence 


**ICD-O-3 Mapping**

  * Iker suggested that NCI Metatethaurus provides mapping of ICD-O-3 to SNOMED and some other vocabularies

  * Memorial Sloan Kettering (MSK) Oncotree mapping

At MSK we maintain a cancer tumor terminology called oncotree  (which is publicly available)
http://oncotree.mskcc.org/oncotree/
 
We also have a public API that maps ICDO site and histology combinations to Oncotree concepts, which at the same time are mapped to NCI Thesaurus and UMLS, see 
http://oncotree.mskcc.org/oncotree-mappings/
 
An example for that API would be 
http://oncotree.mskcc.org/oncotree-mappings/crosswalk?vocabularyId=ICDO&conceptId=&histologyCode=8490/3&siteCode=C16.1