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research:bisphosphonates_and_hip_fracture

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research:bisphosphonates_and_hip_fracture [2017/03/24 18:16]
marc_suchard created
research:bisphosphonates_and_hip_fracture [2017/12/14 05:54] (current)
schuemie
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-====== Comparative effectiveness of alendronate and risedronate ​in reducing the risk of hip fracture ======+====== Comparative effectiveness of alendronate and raloxifene ​in reducing the risk of hip fracture ======
  
 <WRAP box justify round> <WRAP box justify round>
  
-**Objective:​** To compare the effectiveness in reducing the risk of hip fracture between alendronate and risedronate.+**Objective:​** To compare the effectiveness in reducing the risk of hip fracture between alendronate and raloxifene.
  
 **Rationale:​** Osteoporosis is characterized by decreased bone mass and deterioration of bone tissue, resulting in reduced bone strength and increased fracture risk. Approved therapies for osteoporosis include bisphosphonates,​ calcitonin, raloxifene and teriparatide. ​ Among these drugs, alendronate and raloxifene are the most popular osteoporosis medication and a burden of prescription are performed annually. **Rationale:​** Osteoporosis is characterized by decreased bone mass and deterioration of bone tissue, resulting in reduced bone strength and increased fracture risk. Approved therapies for osteoporosis include bisphosphonates,​ calcitonin, raloxifene and teriparatide. ​ Among these drugs, alendronate and raloxifene are the most popular osteoporosis medication and a burden of prescription are performed annually.
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 ** Additional Participants:​** ​ Jon Duke; George Hripcsak; David Madigan; Christian Reich; Patrick Ryan; Martijn Schuemie; ** Additional Participants:​** ​ Jon Duke; George Hripcsak; David Madigan; Christian Reich; Patrick Ryan; Martijn Schuemie;
  
-**Full Protocol:** //<coming soon>//+**Full Protocol:​** ​[[https://github.com/OHDSI/StudyProtocols/​blob/​master/​AlendronateVsRaloxifene/​extras/​alendronate_raloxifene_hip_fracture.docx?​raw=true|Protocol]]
  
 **Initial Proposal Date:** March 21, 2017  **Initial Proposal Date:** March 21, 2017 
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 </​WRAP>​ </​WRAP>​
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 ===== Requirements ===== ===== Requirements =====
 **CDM:** V5 **CDM:** V5
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 ===== Code =====  ===== Code ===== 
-[[https://​github.com/​OHDSI/​StudyProtocols]]+[[https://​github.com/​OHDSI/​StudyProtocols/​tree/​master/​AlendronateVsRaloxifene]]
  
 ===== Discussion =====  ===== Discussion ===== 
research/bisphosphonates_and_hip_fracture.1490379384.txt.gz · Last modified: 2017/03/24 18:16 (external edit)