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Questions of causality are fundamental inspirations behind innovations in philosophy, business, and science, including biomedicine. Answering causal questions leads to better predictive and prescriptive modeling. It is also the key to the correct identification of unknown effects as well as the latent factors that influence outcomes, and to produce hypotheses, validation, and proof. | Questions of causality are fundamental inspirations behind innovations in philosophy, business, and science, including biomedicine. Answering causal questions leads to better predictive and prescriptive modeling. It is also the key to the correct identification of unknown effects as well as the latent factors that influence outcomes, and to produce hypotheses, validation, and proof. | ||
- | We are seeking to rethink the existing frameworks of causal inference in health sciences by introducing ideas from other scientific disciplines and inventing new concepts and analytical methods. | + | Large-scale observational data offers a new window for verifying our existing causal understandings and for inferring new causal relationships at a fast pace. We are working to rethink the existing frameworks of causal inference in health sciences by introducing ideas from other scientific disciplines and by inventing new concepts and analytical methods. |
- | * Please add your name in the following if you are interested to join. | + | * If you are working in causal inference add your project in the following. Also, you can find projects to collaborate or join to stay informed. |
- | * If you have an ongoing project in causal inference in observational biomedical/ health data, please add the project name/link and a two line description to the projects section | + | |
- | * If you have an idea on causal inference that you want to test it or even develop it, join and you will find collaborators here | + | |
- | **Project Lead:** | + | * If you have an idea on causal inference that you want to test it or even develop it, you probably will find collaborators here |
- | [[https://www.linkedin.com/in/ashojaee/|Abbas Shojaee]] | + | |
- | | + | |
- | ** Participants: ** | ||
+ | ** Project Lead:** | ||
+ | * [[https://www.linkedin.com/in/ashojaee/|Abbas Shojaee]] | ||
+ | | ||
- | Menelaos Konstantinidis | + | ===== Ongoing Projects ===== |
- | + | ==== Causal Inference Using Composition of Transactions (CICT) ==== | |
- | Yalda Aryan | + | |
- | + | ||
- | Alireza Aani | + | |
- | ** Ongoing Projects ** | ||
- | Causal Inference Using Composition of Transactions | + | CICT is a novel computational method that uses large-scale health data to predict potential causal relationships between clinical conditions. A pipeline for epidemiological etiological inference is also developed to validate the results of CICT. CICT and the validation pipeline have been used by different teams to identify latent risk factors and unknown effects of clinical conditions or procedures, which resulted in reporting of multiple novel findings during 2018-2019. Two large-scale population-level claims datasets from HCUP California and Florida have been used for discovery and validation. OHDSI will be used to empower the engine for the new phase. |
+ | *** Participants: *** | ||
+ | * Alireza Aani | ||
+ | * Yalda Aryan | ||
+ | * Menelaos Konstantinidis | ||
**Repository:** | **Repository:** |